CAS: 867-81-2; Sodium (R)-3-(2,4-Dihydroxy-3,3-Dimethylbutanamido)Propanoate

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79-83-4 16485-10-2 81-13-0

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CAS号79-83-4 泛酸

专利信息

专利号:WO-9511893-A1
优先权日:1993-10-27
标题 :Compounds and methods for synthesizing pantethine, pantetheine and derivatives thereof
发明人：PATIL GHANSHYAM
权利人:OCULON CORP
摘要:There is disclosed compounds and methods for the synthesis of pantethine, pantetheine, and derivatives thereof. The methods utilize crystalline derivatives of the above compounds as intermediates which readily permit purification by recrystallization, and thus allow the generation of highly pure products. The synthesis utilizes the 1,3-diol functional group present in pantothenic acid to produce the crystalline derivatives by formation of ketal intermediates. Subsequent hydrolisis of the ketal intermediates yields pantethine or pantetheine in highly pure form.

专利号:US-2442143-A
优先权日:1941-06-06
标 题 :Synthesis of pantothenic acid and its salts
发明人：PICKEL FRANK D; WEINSTOCK JR HARRY H
权利人:NOPCO CHEM CO

专利号:US-2009048153-A1
优先权日:2004-12-03
标题:Composition for treating sulfur mustard toxicity and methods of using same
发明人：VARMA SHAMBHU D; PETRALI JOHN
权利人:UNIV MARYLAND; US GOV SEC ARMY
摘要:One embodiment of the present invention provides a composition, comprising, in amounts effective to treat sulfur mustard or half sulfur mustard induced toxicity or skin damage: an agent that inhibits alkylation of —SH and >NH protein groups; an agent that reduces —SS— to SH; a scavenger of reactive oxygen species; a substrate that maintains tissue reduction-oxidation status; an agent that protects against invading inflammatory cells and associated oxidative stress; an antagonist of prostaglandin synthesis; and an agent that induces tissue regeneration. Methods of using the composition are also provided.

专利号:WO-2009016025-A1
优先权日:2007-07-31
标 题 :Process for the synthesis of na- beta-alaninate and calcium pantothenate

专利号:US-7989187-B2
优先权日:2002-07-03
标 题 :Microorganisms and processes for enhanced production of pantothenate
发明人：YOCUM ROGERS R; PATTERSON THOMAS A; PERO JANICE G; HERMANN THERON
权利人:BASF SE
摘要:The present invention features improved methods for the enhanced production of pantoate and pantothenate utilizing microorganisms having modified pantothenate biosynthetic enzyme activities and having modified methylenetetrahydrofolate (MTF) biosynthetic enzyme activities. In particular, the invention features methods for enhancing production of desired products by increasing levels of a key intermediate, ketopantoate, by increasing enzymes or substrates that contribute directly or indirectly to its synthesis. Recombinant microorganisms and conditions for culturing same are also are featured. Also featured are compositions produced by such microorganisms.

专利号:US-7244593-B2
优先权日:2001-01-19
标 题:Microorganisms and processes for enhanced production of pantothenate
发明人：YOCUM R ROGER; PATTERSON THOMAS A; PERO JANICE G; HERMANN THERON
权利人:BASF AG
摘要:The present invention features improved methods for the enhanced production of pantoate and pantothenate utilizing microorganisms having modified pantothenate biosynthetic enzyme activities and having modified methylenetetrahydrofolate (MTF) biosynthetic enzyme activities. In particular, the invention features methods for enhancing production of desired products by increasing levels of a key intermediate, ketopantoate by enzymes that contribute to its synthesis. Recombinant microorganisms and conditions for culturing same are also are featured. Also featured are compositions produced by such microorganisms.