CAS: 3607-17-8; (3-Bromopropyl)Triphenylphosphonium Bromide

上下游产品

CAS号603-35-0 三苯基膦 | CAS号109-64-8 1,3-二溴丙烷 | CAS号51860-45-8 (3-羟丙基)三苯基溴化鏻 | CAS号214116-83-3 1-chloro-4-[(4-... | CAS号214116-80-0 1-chloro-4-(cyc... | CAS号27710-82-3 [3-(二甲基氨基)丙基]三苯... | CAS号7333-67-7 三亚甲基双(三苯基溴化膦) | CAS号30698-18-1 (3-(苯甲酰基氧基)丙基)三苯基溴化膦 | CAS号14114-05-7 环丙基三苯基溴化膦 | CAS号16510-27-3 1-环丙基甲基-4-甲氧基-苯 | CAS号14114-06-8 cyclopropyliden... | CAS号18355-96-9 奥洛他定磷盐 | CAS号14633-95-5 CYCLOPROPYLIDEN...

三苯基膦置于氢溴酸体系中,用 N,N-二甲基甲酰胺 用作溶剂,化学反应 34.0H,反应生成(3-溴丙基)三苯基溴化磷
参考文献:线粒体靶向二氢吡啶衍生物及制备方法及应 用
标题:线粒体靶向二氢吡啶衍生物及制备方法及应 用
摘要:本发明公开了线粒体靶向二氢吡啶类化合物的制备方法及应用,线粒体靶向二氢吡啶类化合物具有式(ⅰ)和(ⅱ)所示结构:实验证明,本发明的线粒体靶向二氢吡啶类化合物能有效清除电离辐射所产生的活性氧(Ros),因此在自由基导致的相关疾病,诸如阿尔兹海默病和电离损伤疾病治疗方面有用途.本制备方法简单,产品易得,无污染.

专利信息

专利号:US-8828984-B2
优先权日:2012-11-19
标题:Gold(III) complexes containing N-heterocyclic carbene ligand, synthesis, and their applications in cancer treatment and thiol detection
发明人：CHE CHI MING; ZOU TAOTAO
权利人:UNIV HONG KONG; UNIV HONG KONG
摘要:Provided herein is a method of synthesis of Au(III)-NHC complexes, a pharmaceutical composition comprises thereof. Also provided herein are the methods for the treatment and prevention of cancer/tumor in patients in need thereof by the administration of the Au(III)-NHC complexes. Also provided is method of detecting thiol in a biological system. The Au(III)-NHC complexes possess anticancer activity such as the induction of cell death, inhibition of cellular proliferation, inhibition of thioredoxin reductase activity, and inhibition of tumor growth in vivo.