CAS: 12035-36-8; Oxo(Oxonickeliooxy)Nickel

专利信息

专利号:US-4080334-A
优先权日:1968-11-22
标题:Intermediates in the total synthesis employing substituted isoxazole derivatives
发明人：SAUCY GABRIEL; SCOTT JOHN WILLIAM
权利人:HOFFMANN LA ROCHE
摘要:The intermediates and processes of this invention provide a new synthetic route for the preparation of pharmaceutically valuable 19-norsteroids. Further, the intermediates and processes of the invention provide a route for the preparation of pharmaceutically valuable estrones. The present invention provides a facile total synthesis of 19β-alkyl-C/D-trans-steroidal materials. This desirable result is obtained via a unique asymmetric induction followed by subsequent stereo-specific reaction steps. As a precursor to the steroidal Ring A, a 3,5-disubstituted-4-isoxazolylmethylene group is employed in this synthesis.

专利号:US-3985771-A
优先权日:1968-11-22
标题:Total steroid synthesis employing substituted isoxazole derivatives
发明人：SAUCY GABRIEL; SCOTT JOHN WILLIAM
权利人:HOFFMANN LA ROCHE
摘要:The novel intermediates and processes of this invention provide a new synthetic route for the preparation of pharmaceutically valuable 19-nor-steroids. Further, the intermediates and processes of the invention provide a novel route for the preparation of pharmaceutically valuable estrones. The present invention provides a facile total synthesis of 13β-alkyl-C/D-trans-steroidal materials. This desirable result is obtained via a unique asymmetric induction followed by subsequent stereo-specific reaction steps. As a precursor to the steroidal Ring A, a 3,5-disubstituted-4-isoxazolylmethylene group is employed in this synthesis.

专利号:US-4044004-A
优先权日:1968-11-22
标题 :Total steroid synthesis employing substituted isoxazole derivatives
发明人：SAUCY GABRIEL; SCOTT JOHN WILLIAM
权利人:HOFFMANN LA ROCHE
摘要:The novel intermediates and processes of this invention provide a new synthetic route for the preparation of pharmaceutically valuable 19-norsteroids. Further, the intermediates and processes of the invention provide a novel route for the preparation of pharmaceutically valuable estrones. The present invention provides a facile total synthesis of 19β-alkyl-C/D-trans-steroidal materials. This desirable result is obtained via a unique asymmetric induction followed by subsequent stereospecific reaction steps. As a precursor to the steroidal Ring A, a 3,5-disubstituted-4-isoxazolylmethylene group is employed in this synthesis.

专利号:WO-9705062-A1
优先权日:1995-08-02
标题:Synthesis of lithiated transition metal oxides
发明人：WOLSTENHOLME JACK; LI WU; CURRIE JOHN C; DUBOIS MAURICE
权利人:WESTAIM TECHNOLOGIES INC
摘要:A synthesis for lithiated transition metal oxide powders is provided which comprises reacting one or more transition metal compounds with a lithium compound, wherein the lithium compound is in a molten phase. The reaction mixture may contain additives, which act primarily to extend the temperature range of the molten phase of the lithium compound.

专利号:US-7488465-B2
优先权日:2003-11-26
标题 :Solid state synthesis of lithium ion battery cathode material
发明人：EBERMAN KEVIN W; SCANLAN JEROME E; GOODBRAKE CHRIS J
权利人:3M INNOVATIVE PROPERTIES CO
摘要:Single-phase lithium-transition metal oxide compounds containing cobalt, manganese and nickel can be prepared by wet milling cobalt-, manganese-, nickel- and lithium-containing oxides or oxide precursors to form a finely-divided slurry containing well-distributed cobalt, manganese, nickel and lithium, and heating the slurry to provide a lithium-transition metal oxide compound containing cobalt, manganese and nickel and having a substantially single-phase O3 crystal structure. Wet milling provides significantly shorter milling times than dry milling and appears to promote formation of single-phase lithium-transition metal oxide compounds. The time savings in the wet milling step more than offsets the time that may be required to dry the slurry during the heating step.

专利号:US-3838163-A
优先权日:1968-11-22
标题 :Substituted isoxazole derivatives as steroid intermediates
发明人：SAUCY G; SCOTT J
权利人:HOFFMANN LA ROCHE
摘要:THE NOVEL INTERMEDICATES AND PROCESSES OF THIS INVENTION PROVIDES A NEW SYNTHETIC ROUTE FOR THE PREPARATION OF PHARMACEUTICALLY VALUABLE19-NOR-STEROIDS. FURTHER, THE INTERMEDICATES AND PROCESSES OF THE INVENTION PROVIDE A NOVEL ROUTE FOR THE PREPARATION OF PHARMACEUTICALLY VALUABLE ESTRONES. THE PRESENT INVENTION PROVIDES A FACILE TOTAL SYNTHESIS OF 13B-ALKYL-C D-TRANS-STEROIDAL MATERIALS. THE DESIRABLE RESULT IS OBTAINED VIA A UNIQUE ASYMMETRIC INDUCTION FOLLOWED BY SUBSEQUENT STEREO-SPECIFIC REACTION STEPS. AS APRECURSOR TO THE SUBSEQUENT STEREOIDAL RING A, A 3,5-DISUBSTI 4-ISOXAZOLYLMETHYLENE GROUO IS EMPLOYED IN THIS SYNTHESIS.