CAS: 144506-14-9; (E)-3-(4-Hydroxy-2-Methoxy-3-(3-Methylbut-2-En-1-yl)Phenyl)-1-(4-Hydroxyphenyl)Prop-2-En-1-One

上下游产品

2,4-Dihydroxybenzaldehyde 2-methyl-3-buten-2-ol 2,4-dihydroxy-3-(3-methyl-2-but-en-1-yl)benzaldehyde 14H18O4C14H18O4

2-Hydroxy-3-(3-Methylbut-2-En-1-yl)-4-[(Tetrahydro-2H-Pyran-2-yl)Oxy]Benzaldehyde置于4-甲基苯磺酸吡啶,Potassium Carbonate,Potassium Hydroxide体系中,用 甲醇,乙醇,丙酮 用作溶剂,化学反应 12.5H,反应生成甘草查尔酮c
参考文献:Facile Synthesis Of Licochalcone C
标题:Facile Synthesis Of Licochalcone C
摘要:通过使用区域选择性$al_2O_3$介导的c-异戊二烯化,然后在碱性条件下进行常规的claisen-Schmidt缩合,从市售的2,4-二羟基苯甲醛合成了甘草查耳酮c.
Doi:10.5012/bkcs.2014.35.7.1996

专利信息

专利号:WO-2024083930-A1
优先权日:2022-10-18
标 题:Topically applied preparation for improving skin condition
发明人：HEUER ANDREA; HÃœPEDEN JENNIFER
权利人:BEIERSDORF AG
摘要:The invention relates to a topically applied preparation comprising a combination of substances including antimicrobial peptides (AMP), in particular cyclic peptide compounds based on the synthesis of thiazolidine and oxazolidine components, and skin-soothing substances such as menthoxypropanediol, substances to strengthen the skin barrier such as omega-6 fatty acids, and/or flavonoids such as licochalcone, which act synergetically and selectively against pathogenic bacteria, such as S. aureus and C. acnes , however not against skin-commensal bacteria, such as S. epidermidis . The preparations can be used advantageously for the treatment of acne or atopic dermatitis and to care for skin that has been damaged by acne or atopic dermatitis.

专利号:WO-2024083413-A1
优先权日:2022-10-18
标题:Topically applied preparation with antimicrobial peptides
发明人：HEUER ANDREA; HÃœPEDEN JENNIFER
权利人:BEIERDSORF AG
摘要:The invention relates to a topically applied preparation comprising a combination of substances including antimicrobial peptides (AMP), in particular cyclic peptide compounds based on the synthesis of thiazolidine and oxazolidine components, and skin-soothing substances such as menthoxypropanediol, substances to strengthen the skin barrier such as omega-6 fatty acids, and/or flavonoids such as licochalcone, which act synergetically and selectively against pathogenic bacteria, such as S. aureus and C. acnes, however not against skin-commensal bacteria, such as S. epidermidis. The preparations can be used advantageously for the treatment of acne or atopic dermatitis and to care for skin that has been damaged by acne or atopic dermatitis.

专利号:US-8367680-B2
优先权日:2008-03-28
标题:Antibacterial small molecules and methods for their synthesis
发明人：BLACKWELL HELEN E; BOWMAN MATTHEW D; STRINGER JOSEPH R
权利人:WISCONSIN ALUMNI RES FOUND; BLACKWELL HELEN E; BOWMAN MATTHEW D; STRINGER JOSEPH R
摘要:The present invention relates generally to compounds providing antibacterial therapeutic agents and preparations, and related methods of using and making antibacterial compounds. Antibacterial compounds of the present invention include chalcone, alkylpyrimidine, aminopyrimidine and cyanopyridine compounds and derivatives thereof exhibiting minimum inhibitory concentrations (MIC) similar to or less than conventional antibacterial compounds in wide use.