CAS: 192139-90-5; (S,S)-N-(P-Toluenesulfonyl)-1,2-Diphenylethanediamine(Chloro)(P-Cymene)Ruthenium(Ii)

上下游产品

6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2[ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2 (R,R)-N-(p-toluenesulfonyl)-1,2-diphenylethylenediamine N-[(1S,2S)-2-amino-1,2-diphenylethyl]-4-methylbenzenesulfonamide 6-p-cymene)(N-tosyl-1,2-diphenylethylenediamine)][RuH(η6-p-cymene)(N-tosyl-1,2-diphenylethylenediamine)]

[rhcl2(P-Cymene)]2,(1S,2S)-(+)-N-对甲苯磺酰基-1,2-二苯基乙二胺置于三乙胺体系中,用 异丙醇 用作溶剂,化学反应 1.0H,以0.37 G的收率获得(S,S)-N-(对甲苯磺酰)-1,2-二苯乙烷二胺(对异丙基苯)氯化钌(II)
参考文献:Compounds With Antibacterial Activity Against Clostridium
标题:Compounds With Antibacterial Activity Against Clostridium
摘要:本发明涉及具有抗clostridium菌活性的新型化合物(I)的药物,特别是针对clostridium Perfringens,以及包含这些化合物的药物组合物和制备这些化合物的化学过程.

专利信息

专利号:US-8785656-B2
优先权日:2012-02-16
标 题:Telescoping synthesis of 5-amino-4-nitroso-1-alkyl-1H-pyrazole salt
发明人：GEIBEL WOLFRAM; WEBER INGO; OSAN ARMIN; SPECKBACHER MARKUS
权利人:PROCTER & GAMBLE
摘要:A telescoping synthesis of 5-amino-4-nitroso-1-alkyl-1H-pyrazole salt derivatives of formula (I), the compound (I) itself, and its use as an intermediate in the fabrication of 1-alkyl-4,5-diaminopyrazole salts of general formula (IX). The compounds of formula (IX) can be used as precursor dyes in oxidative hair dye compositions. n n n n n n n n n n R is a mono- or poly-substituted or unsubstituted, straight or branched, saturated or mono- or poly-unsaturated, alkyl group. HZ and HZ′ are organic or mineral acids.

专利号:US-6455680-B1
优先权日:2000-12-21
标 题 :Methods utilizing aryl thioimines in synthesis of erythromycin derivatives
发明人：LUKIN KIRILL A
权利人:ABBOTT LAB
摘要:An efficient deoximation technique for use in synthesis of erythromycin derivatives, involving aryl thioimine intermediates is disclosed. The aryl thioimine intermediates can be utilized in a method for protecting a ketone of a ketone-containing erythromycin derivative as a thioimine; a method for deoximating an oxime-containing erythromycin derivative, or a method for preparing a 6-O-alkyl erythromycin derivative. Presently preferred erythromycin derivatives have a C-9 oxime or a C-9 ketone.

专利号:US-6632942-B2
优先权日:2000-05-04
标题:Asymmetric synthesis of piperazic acid and derivatives thereof
发明人：ROBIDOUX ANDREA L C; SERAFINI SIRO; DIETERICH PETRA; LEONARDI STEFANIA; STIBBARD JOHN
权利人:VERTEX PHARMA
摘要:This invention provides a concise, asymmetric synthesis of piperazic acid and derivatives thereof, whereby either the (3S)- or (3R)-enantiomeric form may be obtained with high optical purity. (3S)-piperazic acid is derived from D-glutamic acid through an (R)-2,5-dihydroxyvalerate ester intermediate. After the hydroxy groups are converted to suitable leaving groups, such as mesylates, the ester is treated with a bis-protected hydrazine to provide the desired (3S)-piperazic acid derivative. The (3R) enantiomer of piperazic acid may be similarly obtained starting with L-glutamic acid. The method may also be used to obtain piperazic acid derivatives that have moderate optical purity or are racemic. By this method, piperazic acid derivatives may be obtained that are useful as intermediates for pharmacologically active compounds. For example, certain intermediates of this invention are useful for preparing caspase inhibitors, particularly inhibitors of ICE, through additional steps known in the art.

专利号:US-3855198-A
优先权日:1972-09-29
标 题:Novel intermediates for synthesis of l-(5-oxoprolyl)-l-histidy-l-tryptophyl-l-seryl-l-tyrosyl-l-glycyl-l-leucyl-l-arginyl-l-prolyl-glycine amide
发明人：SARANTAKIS D
权利人:AMERICAN HOME PROD
摘要:A process for the synthesis of LRF, i.e. L-(5-oxoprolyl)-Lhistidyl-L-tryptophyl-L-seryl-L-tyrosyl-glycyl-L-leucyl -Larginyl-L-prolyl-glycine amine by the classical route is described which comprises coupling a tetrapeptide, azide terminated, representing the 3-6 amino acid sequence in LRF with a C-amide terminated tetrapeptide representing the 7-10 amino acid sequence in LRF and thereafter converting the resulting octapeptide to LRF. Novel tetrapeptides and octapeptides useful as intermediates are described.

专利号:US-6881847-B2
优先权日:2001-02-01
标题:Process for the synthesis and recovery of nitramines
发明人：HIGHSMITH THOMAS K; HANKS JAMI M; VELARDE STEPHEN P; BOTTARO JEFFREY
权利人:ALLIANT TECHSYSTEMS INC
摘要:A method is provided for the synthesis of nitramines and the recovery of the nitramines from a clathrate.

专利号:US-11649213-B2
优先权日:2018-09-26
标题 :Synthetic method for the preparation of a 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol compound
发明人：MEISENBACH MARK; MARTIN BENJAMIN; RONDE NIEK JOHANNES; RUIZ CARMEN
权利人:MEREO BIOPHARMA 1 LTD
摘要:Provided is a process for preparing a compound, comprising the steps of a) Reacting a compound of Formula A (Formula A) with the compound 3 (3) to provide the compound 5 (5) or a salt or solvate thereof, wherein R is a linear or branched C1-C5 alkyl. Further provided is the compound 5 or a salt or solvate thereof. (5) The use of these compounds in the synthesis of 3-[5-Amino-4-(3-Cyanobenzoyl)-Pyrazol-1-yl]-N-Cyclopropyl-4-Methylbenzamide is also provided.