CAS: 287-27-4; Thietane

上下游产品

trimethylene carbonate potassium thioacyanate thioacetic acid S-(3-chloropropyl) ester 1.3-chlorobromopropaneThiobutyrolactone 3-chloropropyl p-(methylthio)benzyl sulfide 3-benzylmercaptopropyl bromide 3-bromopropyl p-methoxybenzyl sulfide

1-溴-3-氯丙烷置于potassium Hydrosulfide,氢氧化钾体系中,用 乙醇,水 用作溶剂,化学反应 9.0H,以63%的收率获得硫化环丙烷
参考文献:Synthesis Of 2-Alkyl(Aryl)Thietanes
标题:Synthesis Of 2-Alkyl(Aryl)Thietanes
摘要:Thietane And Its 2-Substituted Derivatives Were Synthesized. A General Preparation Procedure For The Synthesis Of Thietanes Bearing Alkyl And Aryl Substituents In The (X-Position Was Developed. Using This Procedure,2-Substituted Thietanes Can Be Obtained From Cheap And Easily Accessible Raw Materials In Three Steps. 2-R-Thietanes (Where R = H,Ch3,C4H9,C5H11,C6H13,C6H5) And The Corresponding Sulfoxides And Sulfones Were Synthesized And Examined. Intermediate And By-Products Of The Synthesis Were Studied.
Doi:10.1134/s0965544107020089

专利信息

专利号:US-12421534-B2
优先权日:2021-11-10
标 题 :Engineered enzymes and method for the synthesis of diverse tyrosine analogs
发明人：ALMHJELL PATRICK J; ARNOLD FRANCES H
权利人:CALIFORNIA INST OF TECHN
摘要:Provided herein is an engineered tryptophan synthase β-subunit (TrpB) that catalyzes the synthesis of tyrosine, tyrosine analogs, or salts thereof. Also provided herein are methods for preparing tyrosine, tyrosine analogs, or a salt thereof using the engineered TrpB described herein.

专利号:US-4311645-A
优先权日:1980-03-24
标 题 :Synthesis of SRS-active compounds
发明人：ROSENBERGER MICHAEL
权利人:HOFFMANN LA ROCHE
摘要:A chemical synthesis of an SRS-A active compound from the reaction product of 1-halo-2-octyne and the ether of 2-penten-4-yn-1-ol including intermediates in the synthesis, some of which being antagonists of SRS-A useful for treating allergic reactions.

专利号:US-2004266827-A1
优先权日:2003-06-25
标 题 :Convergent asymmetric route to produce a key intermediate towards the synthesis of a garft inhibitor
发明人：NOTZ WOLFGANG REINHARD LUDWIG; MARTINEZ CARLOS ALBERTO
权利人:AGOURON PHARMA
摘要:The invention relates to processes for the preparation of a key intermediate in the synthesis of a GARFT inhibitor of formula (Ia) containing a 4-methyl-substituted thiophene core: n n n wherein said key intermediate has the following formula (I): n n n wherein each of R 1 and R 2 are independently a moiety that together with the attached CO 2 forms a readily hydrolyzable ester group; n from a compound of the formula (VI): n n n wherein R 1 is as described above, Pg 1 is an amino protecting group, and Pg 2 is an ether protecting group; wherein said processes are as described in the specification.

专利号:US-11858953-B2
优先权日:2018-04-04
标 题:Compositions and methods for synthesis of phosphorylated molecules
发明人：CHAPUT JOHN; LIAO JEN-YU; BALA SAIKAT
权利人:UNIV CALIFORNIA
摘要:The invention provides compositions and methods for synthesis of phosphorylated organic compounds, including nucleoside triphosphates.

专利号:US-8735586-B2
优先权日:2007-06-26
标 题 :Regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles
发明人：ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARÉ MARC; URMANN MATTHIAS; HALLAND NIS; RKYEK OMAR
权利人:ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARÉ MARC; URMANN MATTHIAS; HALLAND NIS; RKYEK OMAR; SANOFI SA
摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, n nwherein R0; R1; R2; R3; R4; R5; A1; A2; A3; A4, Q and J have the meanings indicated in the claims. The present invention provides a direct copper catalyzed regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.

专利号:US-7429658-B2
优先权日:2003-09-11
标题 :Synthesis of protected pyrrolobenzodiazepines
发明人：HOWARD PHILIP; MASTERSON LUKE
权利人:SPIROGEN LTD
摘要:A method of synthesis of a N-10 protected PBD compound of formula (I): n nvia an intermediate of formula (II) or formula (V):