CAS: 617-05-0; Ethyl 4-Hydroxy-3-Methoxybenzoate

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CAS号121-34-6 香草酸 | CAS号64-17-5 乙醇 | CAS号75-03-6 碘乙烷 | CAS号78-39-7 原乙酸三乙酯 | CAS号1847-84-3 Carbonic acid, ... | CAS号90-05-1 愈创木酚 | CAS号100377-63-7 4-羟基-3-甲氧基苯甲酰肼 | CAS号1486-53-9 4-苄氧基-3-甲氧基苯甲酸 | CAS号7152-90-1 Benzoic acid,4-... | CAS号196194-41-9 ethyl 3-methoxy... | CAS号97966-31-9 3-乙氧基-4-甲氧基苯甲酸甲酯 | CAS号98033-66-0 5-[5-[4-(4,5-di...

香草酸 反应生成 香草酸乙酯
参考文献:Treatment Of Irritable Bowel Syndrome And Nonulcer Dyspepsia With Substituted 2,3-Benzodiazepines
标题:Treatment Of Irritable Bowel Syndrome And Nonulcer Dyspepsia With Substituted 2,3-Benzodiazepines
摘要:根据公式i披露的化合物,其中r1,R2,R3,R4,R5和r6如本文所定义,用于治疗肠易激综合征和非溃疡性消化不良.

专利信息

专利号:US-7339065-B2
优先权日:2003-07-21
标题 :Design and synthesis of optimized ligands for PPAR
发明人：AVERY MITCHELL A; PERSHADSINGH HARRIHAR A
权利人:BETHESDA PHARMACEUTICALS INC; UNIV MISSISSIPPI
摘要:This invention provides new chemical entities useful for treating a variety of clinical disorders including those that are influenced by the activity of peroxisome proliferator activated receptors (PPAR). The structures of the compounds and methods to design, make and use the compounds are provided. Compounds and methods for administering therapeutic compositions comprising the compounds in cases of the disease psoriasis are provided. An exemplary compound having the formula compound is 5adamantan-2-yl-pentanoic acid {2-[4-(2,4-dioxo-thiazolidin-5-yl-methyl)-phenoxy]-ethyl}-methyl-amide is provided.

专利号:US-2007099969-A1
优先权日:2003-07-21
标题 :Design and synthesis of optimized ligands for ppar

专利号:US-8524740-B2
优先权日:2010-07-15
标 题 :Synthesis and anticancer activity of aryl and heteroaryl-quinolin derivatives
发明人：KUO SHENG-CHU; LEE KUO-HSIUNG; HUANG LI-JIAU; CHOU LI-CHEN; WU TIAN-SHUNG; WAY TZONG-DER; CHUNG JING-GUNG; YANG JAI-SING; HUANG CHI-HUNG; TSAI MENG-TUNG
权利人:KUO SHENG-CHU; LEE KUO-HSIUNG; HUANG LI-JIAU; CHOU LI-CHEN; WU TIAN-SHUNG; WAY TZONG-DER; CHUNG JING-GUNG; YANG JAI-SING; HUANG CHI-HUNG; TSAI MENG-TUNG; TAIRX INC
摘要:A compound of Formula I is disclosed as follows: n n n n n n n n n n n n or a pharmaceutically acceptable salt, prodrug, solvate, or metabolite thereof, wherein n R is hydrogen, P(â•?O)(OH) 2 , P(â•?O)(O(C 1 -C 18 )alkylene(C 6 -C 20 )aryl) 2 , P(â•?O)(OH)(OM), P(â•?O)(OM) 2 , Pâ•?O(O 2 M), S(â•?O)(OH) 2 , S(â•?O)(O(C 1 -C 18 )alkylene(C 6 -C 20 )aryl) 2 , S(â•?O)(OH)(OM), S(â•?O)(OM) 2 ; n M is a monovalent or divalent metal ion, or alkylammonium ion; n W is (C 6 -C 20 )aryl, (C 6 -C 20 )heteroaryl, (C 1 -C 18 )alkyl(C 6 -C 20 )aryl, (C 1 -C 18 )alkyl(C 6 -C 20 )heteroaryl, hydroxy(C 6 -C 20 )aryl, hydroxy(C 6 -C 20 )heteroaryl, (C 1 -C 18 )alkoxy(C 6 -C 20 )aryl, (C 1 -C 18 )alkoxy(C 6 -C 20 )heteroaryl, (C 1 -C 18 )alkylenedioxy(C 6 -C 20 )aryl, (C 1 -C 18 )alkylenedioxy(C 6 -C 20 )heteroaryl, halo(C 6 -C 20 )aryl, halo(C 6 -C 20 )heteroaryl, (C 1 -C 18 )alkylamino(C 6 -C 20 )aryl, (C 1 -C 18 )alkylamino(C 6 -C 20 )heteroaryl, (C 1 -C 18 )cycloalkylamino(C 6 -C 20 )aryl, or (C 1 -C 18 )cycloalkylamino(C 6 -C 20 )heteroaryl, and their OR 8 substutes; n R 5 is (C 1 -C 18 alkoxy, hydrogen, hydroxyl, O—(C 1 -C 18 )alkyl(C 6 -C 20 )aryl, halo or OR 8 , or R 5 and R 6 are (C 1 -C 18 )dioxy provided that R 7 is hydrogen; n R 6 is hydroxyl, O—(C 1 -C 18 )alkyl(C 6 -C 20 )aryl, halo or OR 8 , (C 1 -C 18 )alkoxy, (C 1 -C 18 )alkylamino, or (C 1 -C 18 )cycloalkylamino, or R 6 and R 7 are (C 1 -C 18 )dioxy provided that R 5 is hydrogen; n R 7 is hydrogen, halo or OR 8 , hydroxyl, or O—(C 1 -C 18 )alkyl(C 6 -C 20 )aryl; and n R 8 is P(â•?O)(OH) 2 , P(â•?O)(O(C 1 -C 18 )alkyl(C 6 -C 20 )aryl) 2 , Pâ•?O)(OH)(OM), or P(â•?O)(OM) 2 , Pâ•?O(O 2 M).

专利号:WO-2013002253-A1
优先权日:2011-06-27
标 题 :Method for producing benzophenone derivative
发明人：MATSUMURA TSUTOMU; SAITOH TOSHIKAZU; TAKEMURA KAZUNOBU; KOBAYASHI KENTARO; NITTA MARIKO; HAGIHARA KOJI
权利人:KYOWA HAKKO KIRIN CO LTD; MATSUMURA TSUTOMU; SAITOH TOSHIKAZU; TAKEMURA KAZUNOBU; KOBAYASHI KENTARO; NITTA MARIKO; HAGIHARA KOJI
摘要:Provided are: a compound represented by general formula (I) (wherein R 1a and R 1b may be the same as or different from each other and independently represent a benzyl group substituted by one to three halogen atoms, wherein, when the number of the halogen atoms is two or three, the halogen atoms may be the same as or different from each other; R 2 represents a lower alkyl group which may have a substituent; and R 3 represents a lower alkoxycarbonyl group which may have a substituent) or a salt thereof, which is useful in, for example, a method for producing an intermediate for the synthesis of a benzophenone derivative having an anti-tumor activity and the like; a method for producing a benzophenone derivative represented by general formula (III) (wherein R 1a , R 1b , R 2 and R 3 are as defined above; R 4 represents a lower alkyl group which may have a substituent; and R 5 represents an aliphatic heterocyclic alkyl group which may have a substituent) or a salt thereof, the method being characterized by comprising reacting a compound represented by general formula (II) (wherein R 4 and R 5 are as defined above) or a salt thereof in the presence of an acid; and others.

专利号:CN-114957200-A
优先权日:2022-05-31
标 题:Synthesis of key intermediates of anticancer drug icotinib

专利号:WO-02076177-A2
优先权日:2001-03-23
标 题:Design and synthesis of optimized ligands for ppar