CAS: 1679-53-4; 10-Hydroxydecanoic Acid

上下游产品

正癸酸 1-Decanoic Acid 334-48-5
癸二酸 1,10-Decanedioic Acid 111-20-6
2-十一烯酸 10-Undecenoic Acid 112-38-9
10-Hydroxydecanal 22136-92-1
7-溴庚酸 7-Bromoheptanoic Acid 30515-28-7
10-羟基癸酸甲酯 Methyl 10-Hydroxydecanoate 2640-94-0
10-羟基-8-癸炔酸 10-Hydroxy-8-Decynoic Acid 92016-00-7
16-Hydroxy-Hexadec-6-Enoic Acid 4444-16-0 10-Hydroxy-Decin-(7)-Saeure 91057-51-1 Methyl 10-Undecynoate 2777-66-4

正癸酸置于cytochrome P450 Glucose-6-Phosphate Dehydrogenase,α-D-吡喃葡萄糖6-磷酸,还原型辅酶ii(Nadph)四钠盐体系中,用 Phosphate Buffer 用作溶剂,化学反应 1.0H,反应生成10-羟基癸酸
参考文献:Molecular Cloning Of Cyp76B9,A Cytochrome P450 Frompetunia Hybrida,Catalyzing The ω-Hydroxylation Of Capric Acid And Lauric Acid
标题:Molecular Cloning Of Cyp76B9,A Cytochrome P450 Frompetunia Hybrida,Catalyzing The ω-Hydroxylation Of Capric Acid And Lauric Acid
摘要:从杂交牵牛花(petunia Hybrida)中分离出了一种编码细胞色素p450(cyp76B9)的cdna.北方印迹分析显示该基因在花朵和叶子中有优先表达.表达cyp76B9的重组酵母微粒体与癸酸和月桂酸作为底物反应.经过与表达cyp76B9的酵母微粒体孵育后,从每种脂肪酸中产生了一种主要代谢产物.通过气相色谱-质谱联用(gc-Ms),这些代谢产物被鉴定为ω-羟基癸酸和ω-羟基月桂酸.反应的动力学参数为:癸酸的k_m=9.4 μm,V_max=每摩尔p450 13.6 Mol Min−1;月桂酸的k_m=5.7 μm,V_max=每摩尔p450 19.1 Mol Min−1.我们发现癸酸和月桂酸的ω-羟基代谢产物会影响阿拉伯芥(arabidopsis Thaliana)的植物生长.在存在ω-羟基脂肪酸的条件下生长的植物,其根长度比对照组(使用相应的非羟基化脂肪酸)短.
Doi:10.1271/bbb.60396

专利信息

专利号:US-9023626-B2
优先权日:2007-09-20
标 题:Methods for the synthesis of fatty diacids by the metathesis of unsaturated diacids obtained by fermentation of natural fatty acids
发明人：DUBOIS JEAN-LUC
权利人:DUBOIS JEAN-LUC; ARKEMA FRANCE
摘要:The invention relates to a method for the synthesis of diacids of general formula ROOC—(CH 2 ) n —(CHâ•?CH) a —(CH 2 ) m COOR 1 in which n and m are identical or different and each represent an integer such that their sum is between 6 and 15, a is an index of 0 or 1, and R and R 1 are H or an alkyl radical with 1 to 4 carbon atoms, from long-chain mono-unsaturated natural fatty acids or esters having at least 10 adjacent carbon atoms per molecule of the general formula CH 3 —(CH 2 ) p —CHâ•?CH—(CH 2 ) q —COOR, p and q, being identical or different and representing indices between 2 and 11, wherein said method comprises the first step of oxidizing by fermentation said natural fatty acid or ester, using a microorganism, such as a bacterium, a yeast, or a fungus, into at least one unsaturated dicarboxylic acid or dicarboxylate, the second step of submitting the product from the first step to a metathesis crossed with a compound of formula R 2 OOC—(CH 2 ) x —CHâ•?CH—R 3 , in which R 2 is H or an alkyl radical with 1 to 4 carbon atoms, x is 0 or 1 or 2, and R 3 is H, CH 3 or COOR 2 , in order to obtain the unsaturated compound of formula ROOC—(CH 2 ) q —CHâ•?CH—(CH 2 ) x —COOR 2 , and the third optional step of converting the usaturated compound into a saturated compound by hydrogenation of the double bond.

专利号:US-6171614-B1
优先权日:1996-10-15
标 题 :Synthesis of glycophospholipid and peptide-phospholipid conjugates and uses thereof
发明人：CHAIKOF ELLIOT L; SUN LIJUN
权利人:UNIV EMORY
摘要:The present invention provides glycophospholipid and peptide-phospholipid conjugates comprising a phospholipid moiety and a saccharide or peptide moiety joined by an ether linkage comprising a secondary or tertiary amine. The conjugate structure of the invention comprises a flexible spacer arm between the phospholipid and saccharide or peptide moieties which, being variable in length, serves to optimize saccharide or peptide bioactivity. This invention further provides a method for the synthesis of such conjugates comprising the step of reductive amination. The method is efficient, economical and provides a high yield of product. Glycophospholipid and peptide-phospholipid conjugates of the invention can be incorporated and, optionally, chemically polymerized in self-assembling systems such as membranes, bilayers, films, liposomes and the like, and find utility diagnostically and therapeutically in medical and immuno-biological applications.

专利号:US-8940923-B2
优先权日:2007-06-13
标题:Method for the synthesis of diacids or diesters from natural fatty acids and/or esters
发明人：DUBOIS JEAN-LUC
权利人:ARKEMA FRANCE
摘要:Disclosed herein a process for the synthesis of diacids or diesters of general formula ROOC—(CH 2 )x-COOR, in which n represents an integer between 5 and 14 and R is either H or an alkyl radical of 1 to 4 carbon atoms, starting from long-chain natural monounsaturated fatty acids or esters comprising at least 10 adjacent carbon atoms per molecule, of formula CH 3 —(CH 2 )n-CHR 1 —CH 2 —CHâ•?CH—(CH 2 )p-COOR, in which R represents H or an alkyl radical comprising from 1 to 4 carbon atoms, R 1 is either H or OH, and n and p, which are identical or different, are indices between 2 and 11.

专利号:US-7754646-B2
优先权日:2001-06-29
标 题 :Synthesis and use of organosilica particles
发明人：TRAU MATHIAS; JOHNSTON ANGUS
权利人:NANOMICS BIOSYSTEMS PTY LTD
摘要:Highly functionalized, porous organosilica particles and methods of their synthesis are described that employ high amounts of functional silane such as 3-mercaptopropyl trimethoxysilane. Silane particle diameters are controlled from less than 1 μm to over 100 μm. The particles have a high surface area due to their advantageous internal structures, which consist of large pores, typically up to 10 μm that are linked by small channels of typically about 20 nm diameter. Isothiocyanate modified fluorescent dyes can enter and react with thiol groups inside the pores. The invention also provides clear silica shells of controlled thicknesses to protect fluorescent signals and provide an independent parameter for distinguishing particle types based on light scattering off different sized particles. The particles are stable and useful for many purposes, particularly for optical bar coding in combinatorial synthesis of polymers such as nucleic acid, polypeptide, and other synthesized molecules.

专利号:US-2024254395-A1
优先权日:2021-06-02
标题 :Pyrolysis of polyurethane compound-containing material in order to recover raw materials
发明人：EIDEN STEFANIE; BELLINGHAUSEN RAINER; WOLF AUREL; HAHN CHRISTIAN; LODDENKEMPER TIM; JENDRZOK CAROLA
权利人:COVESTRO DEUTSCHLAND AG
摘要:The invention relates to a process according to claim 1 and pyrolysis devices used therein for the pyrolysis of pyrolysis stock comprising polyurethane-containing material, allowing carrying out pyrolysis on an industrial scale. According to the invention, even with higher amounts of pyrolysis stock an amount of pyrolysis product is obtained that contains cleavage products which can be reused for the synthesis of polyurethane-containing material.

专利号:US-2024352216-A1
优先权日:2021-08-20
标 题:Pyrolysis of a polymeric polyurethane compound in order to recover raw materials
发明人：EIDEN STEFANIE; BELLINGHAUSEN RAINER; WOLF AUREL; ALBACH ROLF
权利人:COVESTRO DEUTSCHLAND AG
摘要:The invention relates to a method according to claim 1 for the commercial implementation of a pyrolysis, and to pyrolysis devices for the pyrolysis of pyrolysis stock used in this method. The pyrolysis stock contains a polymeric compound having at least one structural polyurethane unit of the formula (I), wherein Q is a hydrocarbon group with 2 to 8 carbon atoms, preferably 3 to 8 carbon atoms, and n represents a number from 2 to 4, most preferably 2, and -* represents a covalent bond to the polymer backbone. The method and the pyrolysis device according to the invention allow, even with higher compounds of pyrolysis stock an amount of pyrolysis product to be obtained that contains cleavage products which can be reused for the synthesis of polyurethane-containing material.