CAS: 182289-81-2; 4-Fluoro-2-Nitro-1-(Trifluoromethyl)Benzene

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CAS号367-86-2 3-硝基-4-氟三氟甲苯 | CAS号349-27-9 N-(2-fluoro-5-(... | CAS号535-52-4 2-氟-5-三氟甲基苯胺

2-氟-5-三氟甲基苯胺置于盐酸,亚硝酸特丁酯,硫酸,硝酸体系中,化学反应 3.0H,反应生成4-氟-2-硝基三氟甲苯
参考文献:Synthesis And Qsar Of Herbicidal 3-Pyrazolyl α,α,α-Trifluorotolyl Ethers
标题:Synthesis And Qsar Of Herbicidal 3-Pyrazolyl α,α,α-Trifluorotolyl Ethers
摘要:Pyrazole Nitrophenyl Ethers (Ppes) Were Recently Identified As A Novel Class Of Chemistry Exerting Herbicidal Effects By Inhibition Of Protoporphyrinogen Ix Oxidase. This Area Of Chemistry Has Been Extended To Include Herbicidal Pyrazolyl Fluorotolyl Ethers. In These Compounds,A Trifluoromethyl Group Substitutes For The 4'-Nitro Group Found In The Original Herbicides And In ''Classical'' Nitrodiphenyl Ether Hebicides. Fluoroanisole Pyrazole Ethers,In Which A Trifluoromethoxy Group Replaces The Nitro Group Of Diphenyl Ether Herbicides,Are Also Described. The Shift From 4'-Nitro To 4'-Trifluoromethyl Substitution,Which Is Conservative In Terms Of Electrostatics,Produced A Novel Class Of Herbicide With Substantial Pre-Emergent Activity On Narrowleaf Weed Species. Quantitative Structure/activity Relationships Obtained With Respect To Substitution On The Pyrazole Ring And At The 3'-Position Of The Fluorotolyl Moiety Can Be Summarized Effectively By Comparative Molecular Field Analysis. In General,5-Methanesulfonyl Fluorotoluidide Ethers Were Found To Be Most Active.
Doi:10.1021/jf9601978