CAS: 110611-91-1; 4-(((2R,3S,4R,5R,6R)-6-(Benzyloxy)-3-((Diphenoxyphosphoryl)Oxy)-4-(Tetradecanoyloxy)-5-((S)-3-(Tetradecanoyloxy)Tetradecanamido)Tetrahydro-2H-Pyran-2-yl)Methoxy)-4-Oxobutanoic Acid

专利信息

专利号:US-5679773-A
优先权日:1995-01-17
标题 :Reagants and methods for immobilized polymer synthesis and display
发明人：HOLMES CHRISTOPHER P
权利人:AFFYMAX TECH NV
摘要:Compounds and methods for solid phase synthesis of organic molecules including peptides, oligonucleotides, benzodiazepines, beta -turn mimetics, and prostaglandins. The present invention provides new reagents in the form of linking groups and resins and substrates having attached linking groups which are useful in solid phase synthesis of high density arrays of organic molecules. The invention also provides methods which increase yields of various organic synthesis strategies.

专利号:US-7202092-B2
优先权日:2001-07-13
标题:Indinavir derivatives useful in immunoassay
发明人：GHOSHAL MITALI; SIGLER GERALD; PATWARDHAN ANIRUDDHA P
权利人:ROCHE DIAGNOSTICS OPERATIONS
摘要:Derivatives and conjugates of indinavir for generation of antibodies and labeled conjugates for use for detection of indinavir in biological samples. The derivatives are synthesized out of the indane ring hydroxyl group or the pyridine ring nitrogen of indinavir. Also disclosed is synthesis of a major metabolite of indinavir (M6) in a single step from indinavir using palladium catalyst and hydrogen gas. Indinavir M6 has been extended to synthesize various analogs of indinavir with suitable functional groups. These derivatives are useful in the development of indinavir immunogens, antibodies, and labeled conjugates in the development of indinavir immunoassays.

专利号:US-9994558-B2
优先权日:2013-09-20
标题 :Multicyclic compounds and methods of using same
发明人：BALOGLU ERKAN; SHACHAM SHARON; SENAPEDIS WILLIAM; MCCAULEY DILARA; LANDESMAN YOSEF; GOLAN GALI; KALID ORI; SHECHTER SHARON
权利人:KARYOPHARM THERAPEUTICS INC
摘要:The invention generally relates to compounds represented by Structural Formula I: or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of structural formula I, or a pharmaceutically acceptable salt or composition thereof, e.g., in treatment of cancer (e.g., mantle cell lymphoma), and other diseases and disorders (e.g., PAK-mediated, for example, PAK4-mediated, diseases and disorders).

专利号:US-7208611-B2
优先权日:2005-02-23
标题 :Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use
发明人：GAO QINGZHI; GALLOP MARK A; XIANG JIA-NING
权利人:XENOPORT INC
摘要:Platinum containing compounds exhibiting cytostatic activity, methods of synthesizing platinum-containing compounds exhibiting cytostatic activity pharmaceutical compositions comprising platinum containing compounds, and methods of using such compounds and compositions for treating cancer are disclosed.

专利号:DE-2711008-A1
优先权日:1977-03-14
标题 :2-OXO-ALKANYLIDEN-TRIARYLPHOSPHORANES, PROCESS FOR THEIR PRODUCTION AND THEIR USE FOR THE SYNTHESIS OF NEW PROSTAGLANDIN ANALOGS

专利号:US-2006205677-A1
优先权日:2005-02-23
标题:Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use