CAS: 1149-23-1; Diethyl 1,4-Dihydro-2,6-Dimethyl-3,5-Pyridinedicarboxylate

相似化合物

632-93-9 55536-71-5 19350-66-4

上下游产品

CAS号50-00-0 甲醛 | CAS号141-97-9 乙酰乙酸乙酯 | CAS号631-61-8 乙酸铵 | CAS号6186-89-6 Propanedioic ac... | CAS号14558-49-7 1,3-噁嗪烷 | CAS号626-34-6 3-氨基巴豆酸乙酯 | CAS号1149-24-2 2,6-二甲基吡啶-3,5-二甲酸二乙酯 | CAS号20503-92-8 3-Phenyloxazolidine | CAS号100-97-0 乌洛托品 | CAS号64-17-5 乙醇 | CAS号1149-24-2 2,6-二甲基吡啶-3,5-二甲酸二乙酯 | CAS号5553-92-4 2-(4-甲氧基苄基)丙二腈 | CAS号14258-07-2 diethyl 1,2,6-t... | CAS号20329-31-1 2,4,6-tris(2,2-... | CAS号623-91-6 富马酸二乙酯 | CAS号141-05-9 顺丁烯二甲酸二乙酯 | CAS号123-25-1 丁二酸二乙酯 | CAS号2964-33-2 2-[(4-chlorophe... | CAS号324025-11-8 N-(4-methoxyphe...

2,6-二甲基吡啶-3,5-二甲酸二乙酯置于sodium Cyanoborohydride,溶剂黄146体系中,用 水 用作溶剂,以91%的收率获得二氢吡啶
参考文献:硼酸催化喹啉的化学选择性还原.
标题:硼酸催化喹啉的化学选择性还原.
摘要:硼酸促进了取代喹啉向合成多用途的1,2,3,4-四氢喹啉(1,2,3,4-Thqs)的转移加氢反应,该反应在温和的反应条件下使用汉茨酯作为温和的有机氢源进行了描述.该方法是实用且有效的,其中分离的收率极好,并且在n-杂芳烃部分中可还原的官能团具有非常好的耐受性.通过各种对照实验和NMR研究证明了反应参数和初期机理途径.目前的工作也可以扩大规模以获得克量,并且通过将1,2,3,4-Thqs转化为一系列具有生物学重要性的分子(包括抗心律不齐药物nicainoprol)来说明所开发方法的实用性.
Doi:10.1039/c9Ob02673H

专利信息

专利号:WO-2023027655-A1
优先权日:2021-08-26
标题:Method of synthesis of 1,4-dihydropyridine derivatives in subcritical fluid medium
发明人：GIRAY ELIFE SULTAN; ERSATIR MEHMET; TURK MURAT
权利人:CUKUROVA UNIV REKTORLUGU
摘要:The invention relates to an environmentally friendly, effective, high and excellent yield one-pot synthesis method for the synthesis of Hantzsch 1,4-dihydropyridine derivatives in subcritical EtOH (SbCEtOH) medium.

专利号:US-9556140-B2
优先权日:2013-01-26
标 题 :Approach for synthesis of catechins
发明人：DUGAR SUNDEEP; MAHAJAN DINESH; RAI KUMAR SANTOSH; TRIPATHI VINAYAK; PATIL ISHWAR RAKESH
权利人:SPHAERA PHARMA PRIVATE LTD
摘要:A process for synthesis of enatiomerically pure or enatiomerically enriched or racemic mixture of (+ and/or −) epicatechin and its intermediates, comprising the steps of: (i) obtaining penta-protected quercetin; (ii) reducing the penta-protected quercetin obtained from step (i); (iii) optionally deprotecting the compound of step (ii); (iv) reducing the compound obtained from step (ii) or step (iii) in the presence of a chiral/achiral reducing agent to obtain a chiral intermediate; (v) deprotecting and/or hydrogenation of the chiral intermediate obtained from step (iv) to obtain (−)-epicatechin; (vi) optionally simultaneously deprotecting and by drogenation of the compound obtained from step (ii) to obtain racemic epicatechin.

专利号:WO-2014202765-A1
优先权日:2013-06-21
标题 :Preparation of chiral 1-methyl-2,3,4,5-1h-benzodiazepines via asymmetric reduction of alpha-substituted styrenes
发明人：STAVBER GAJ; GAZIC SMILOVIC IVANA; CLUZEAU JEROME; RICHTER FRANK
权利人:LEK PHARMACEUTICALS
摘要:The present invention provides an asymmetric and economic synthesis of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1 H-benzo[d]azepine via novel intermediates applying an asymmetric enzymatic, biomimetic or catalytic reduction. The present invention also provides a novel green asymmetric catalytic reduction adapted for an aqueous medium to be applied in the synthesis of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1 H-benzo[d]azepine or novel intermediates.

专利号:US-9822053-B2
优先权日:2016-01-28
标题:Single step conversion of N-butyraldehyde to 2-ethylhexanal
发明人：BOPPANA Venkata Bharat; HAMPTON JR KENNETH WAYNE; LIU ZHUFANG; SUMNER JR CHARLES EDWAN; TUSTIN GERALD C; STEINMETZ GUY RALPH; STEFFEY MELISSA PAGE
权利人:EASTMAN CHEM CO
摘要:Disclosed is a method of making and using a titania supported palladium catalyst for the single step synthesis of 2-ethylhexanal from a feed of n-butyraldehyde. This titania supported palladium catalyst demonstrates high n-butyraldehyde conversion but also produces 2-ethylhexanal in an appreciable yield with maintained activity between runs. This method provides a single step synthesis of 2-ethylhexanal from n-butyraldehyde with a catalyst that can be regenerated that provides cleaner downstream separations relative to the traditional caustic route.

专利号:US-10053420-B2
优先权日:2015-01-30
标 题 :Processes for the preparation of compounds, such as 3-arylbutanals, useful in the synthesis of medetomidine
发明人：EKLUND LARS; EEK MARGUS; EKAMBARAM RAMESH; MAASALU ANTS
权利人:CAMBREX KARLSKOGA AB
摘要:There is provided a process for the preparation of a compound of formula (I) as defined herein, wherein said process comprises reacting a compound of formula (II) as defined s herein with one or more suitable Vilsmeier reagent.

专利号:US-12428393-B2
优先权日:2021-02-02
标 题:Methods of making trans isomeric forms of G protein-coupled receptor modulators
发明人：BUCHER CYRIL; DAVIDSON JAMES P; JACKSON JEFFREY J; KO MICHELLE YOO MIN; SHIBUYA GRANT; WUSTROW DAVID J; Younai Ashkaan; ZIBINSKY MIKHAIL
权利人:RAPT THERAPEUTICS INC
摘要:Disclosed herein are methods of synthesis of a trans isomeric form of a C—C chemokine receptor type 4 (CCR4) modulator, or a salt or ester thereof that comprise making a trans isomeric compound of formula (III) by reacting a compound of formula (I) with a compound of formula (II) in the presence of a carboxylic acid directed reducing agent, wherein the compound of formula (III) is in a predominantly trans isomerically pure form.