CAS: 1878-69-9; 2-(3-Iodophenyl)Acetic Acid

上下游产品

CAS号130723-54-5 3-碘苯乙腈 | CAS号201230-82-2 carbon monoxide | CAS号49617-83-6 3-碘苄溴 | CAS号14338-36-4 3-氨基苯乙酸 | CAS号34956-29-1 3-醛基苯乙酸 | CAS号502649-73-2 2-(3-碘苯基)乙酸甲酯

3-碘苄溴置于sodium Cyanide,乙醇体系中,化学反应生成3-碘苯乙酸
参考文献:148.一元羧酸的化学组成和解离常数.第五部分:进一步取代的苯甲酸和苯乙酸
标题:148.一元羧酸的化学组成和解离常数.第五部分:进一步取代的苯甲酸和苯乙酸
摘要:
Doi:10.1039/jr9360000644

专利信息

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-4426536-A
优先权日:1982-06-14
标 题:Synthesis of phenylacetic acid esters
发明人：ROBEY ROGER L
权利人:LILLY CO ELI
摘要:Esters of phenylacetic acids are prepared in a single step by hydrolysis of 2,2,2-trichloro-1-phenylethanes in inorganic basic media.

专利号:US-2013261317-A1
优先权日:2010-09-27
标题 :Methods for preparing synthetic bile acids and compositions comprising the same
发明人：MORIARTY ROBERT M; RAO PHOTON
权利人:MORIARTY ROBERT M; RAO PHOTON; KYTHERA BIOPHARMACEUTICALS INC
摘要:This invention relates generally to methods for preparing certain bile acids from non-mammalian sourced starting materials as well as to synthetic bile acids and compositions comprising such acids wherein the acids are characterized by a different C 14 population than naturally occurring bile acids as well as being free from any mammalian pathogens. This invention is also directed to the synthesis of intermediates useful in the synthesis of such bile acids. Accordingly, the C ring of the steroidal scaffold is oxidized to provide a synthetic route and intermediates to DCA. This invention also provides synthetic methods for preparing deoxycholic acid or a salt thereof starting from aromatic steroids such as estrogen, equilenin, and derivatives thereof. This invention is also directed to intermediates such as 12-oxo or delta-9,11-ene steroids as well as novel processes for their preparation. In preferred embodiments, bile acids are provided herein which have substituents on the B-ring and/or D-ring side chain and optionally on the hydroxy group of the A-ring.

专利号:EP-0098058-A1
优先权日:1982-06-14
标 题 :Synthesis of phenylacetic acid esters

专利号:CN-111170991-B
优先权日:2014-07-11
标题 :Antiproliferative compounds and methods of synthesis thereof

专利号:CN-111170991-A
优先权日:2014-07-11
标 题:Antiproliferative compounds and methods of synthesis thereof