CAS: 380430-57-9; 4-(Methylsulfonylamino)Phenylboronic Acid

上下游产品

CAS号124-63-0 甲基磺酰氯 | CAS号214360-73-3 4-氨基苯硼酸频哪醇酯

甲基磺酰氯,4-氨基苯硼酸频哪醇酯置于吡啶,水体系中,用 二氯甲烷 作为反应溶剂,以99%的收率获得产物4-N-(甲基磺酰胺)苯硼酸
参考文献:[de] Verwendung Von Substituierten 2-Phenylbenzimidazolen Als Arzneimittel Use Of Substituted 2-Phenylbenzimidazoles As Medicaments[fr] Utilisation De 2-Phenylbenzimidazoles Substitues En Tant Que Medicaments
标题:[de] Verwendung Von Substituierten 2-Phenylbenzimidazolen Als Arzneimittel Use Of Substituted 2-Phenylbenzimidazoles As Medicaments[fr] Utilisation De 2-Phenylbenzimidazoles Substitues En Tant Que Medicaments
摘要:这项发明涉及使用式(i)的取代2-苯基苯并咪唑,其中r1,R2,R3,R4,R5和m具有权利要求中所述的含义,用于制备一种药物,用于治疗或预防涉及胰高血糖素受体的疾病,以及式(i)中r1为式(II)的脱氢松香烯基团的新化合物.

专利信息

专利号:US-9708336-B2
优先权日:2014-01-22
标题 :Metallo-beta-lactamase inhibitors
发明人：MANDAL MIHIR; TANG HAIFENG; XIAO LI; SU JING; LI GUOQING; YANG SHU-WEI; PAN WEIDONG; TANG HAIQUN; DEJESUS REYNALDA; HICKS JACQUELINE; LOMBARDO MATTHEW; CHU HONG; HAGMANN WILLIAM; PASTERNAK ALEX; GU XIN; JIANG JINLONG; DONG SHUZHI; DING FA-XIANG; LONDON CLARE; BISWAS DIPSHIKHA; YOUNG KATHERINE; HUNTER DAVID N; ZHAO ZHIQIANG; YANG DEXI
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula (I) that are metallo-β-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with β-lactam antibiotics for overcoming resistance.

专利号:US-2007275968-A1
优先权日:2004-09-07
标 题 :Substituted Biphenyl Derivative
发明人：KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
权利人:KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
摘要:The present invention relates to a biaryl derivative or a pharmacologically acceptable salt thereof having an excellent collagen-synthesis inhibition activity. A biaryl derivative having a structure represented by the following General Formula (I) or a pharmacologically acceptable salt thereof: n nwherein n R 1 represents a C 6 -C 10 aryl group which is substituted with one to three group(s) each independently selected from the group consisting of a group defined by formula R-L-, a di-(C 1 -C 6 alkyl)amino group, a di-(C 1 -C 6 alkyl)aminosulfonyl group, a hydroxyaminocarbonyl group, and a halogen atom, and so on; R represents a C 1 -C 6 alkyl group, and so on; L represents a sulfonyl group, an aminosulfonyl group, or a sulfonylamino group, and so on; R 2 represents a hydrogen atom, and so on; A represents a group defined by formula (II), (III), or (IV); R 3 represents a C 1 -C 6 alkyl group, and so on; and R 4 represents a C 1 -C 6 alkyl group, and so on.