CAS: 6485-40-1; (R)-2-Methyl-5-(Prop-1-En-2-yl)Cyclohex-2-Enone

相似化合物

2244-16-8 99-49-0 99-48-9

上下游产品

(2S,4S)-carveol (+)-trans-carveol oxime (4S)-4-isopropenyl-1-methylcyclohex-1-en-6-one (1E,6R)-4,7,7-trimethylbicyclo[4.1.0]hept-4-en-3-onecarvacrol S)-8-methoxy-p-menth-6-en-2-one(S)-8-methoxy-p-menth-6-en-2-one R)-5-isopropenyl-1,2-dimethyl-cyclohexa-1,3-diene(R)-5-isopropenyl-1,2-dimethyl-cyclohexa-1,3-diene 1-methyl-6-methylene-4-(prop-1-en-2-yl)cyclohex-1-ene

专利信息

专利号:US-8507562-B2
优先权日:2004-07-07
标 题 :Synthesis of (1)-beta-elemene, (-)-beta-elemenal, (-)-beta-elemenol, (-)-beta-elemene fluoride and their analogues, intermediates, and composition and uses thereof
发明人：HUANG LAN
权利人:HUANG LAN; HYWE PHARMACEUTICALS INC
摘要:The present invention provides convergent processes for preparing (−)-beta-elemene, (−)-beta-elemenal, (−)-beta-elemenol, and (−)-beta-elemene fluoride and analogues thereof. Also provided are intermediates useful for preparing (−)-beta-elemene. The present invention further provides novel compositions based on analogues of (−)-beta-elemene, (−)-beta-elemenal, (−)-beta-elemenol, (−)-beta-elemene fluoride and methods for the treatment of cancer, such as brain tumor, lung cancer, breast cancer, prostate cancer, ovarian cancer, colorectal cancer, gastric intestional cancer, and stomach cancer. n The inventors propose a combination therapy using 1) one or more of the following anti-cancer agents: including, but not limited to, Cisplatin, 5-FU, Taxol, Taxol derivatives, and any anti-cancer agent, and 2) one or more of the following (−)-beta-elemene and its analogs, including (−)-beta-elemene, (−)-beta-elemenal, (−)-beta-elemenol, (−)-beta-elemene fluoride, and their analogs, and (−)-beta-elemene's intermediate in its chemical synthesis, for the treatment of cancer, especially for the treatment of brain tumor, lung cancer, ovarian cancer, bladder cancer, cervical cancer, colon cancer, breast cancer, and prostate cancer.

专利号:US-2006014987-A1
优先权日:2003-07-07
标 题:Synthesis of beta-elemene, intermediates thereto, analogues and uses thereof
发明人：HUANG LAN
权利人:HUANG LAN
摘要:The present invention provides convergent processes for preparing beta-elemene, and analogues thereof. Also provided are analogues related to beta-elemene and intermediates useful for preparing the same. The present invention further provides novel compositions based on analogues of beta-elemene and methods for the treatment of cancer, such as brain tumor, lung cancer, colorectal cancer, gastric intestional cancer, and stomach cancer.

专利号:US-11168064-B2
优先权日:2017-03-27
标 题:Synthesis of thapsigargin, nortrilobolide, and analogs thereof
发明人：EVANS P ANDREW; CHEN DEZHI
权利人:UNIV KINGSTON
摘要:The present invention relates to the preparation of compounds of Formula I, including thapsigargin, nortrilobolide and 8-O-debutanoyl-thapsigargin from commercially available (R)-(−)-carvone via synthetic intermediate compound of formula 12 by pinacol coupling and in situ lactonization.

专利号:US-7598408-B2
优先权日:2003-02-25
标 题:Intermediates for synthesis of vitamin D derivatives
发明人：IMAHORI HIDEKAZU; KOYAMA HIROYA; YOSHIHARA DAISUKE; SAWASHITA YOSHINORI; KURITA SOTA; ICHIHARA YOSHIHIRO; TAKAGI YOSHIHIRO; HIROSE KATSUTOSHI
权利人:KNC LAB CO LTD
摘要:The present invention provides a novel intermediate for synthesizing vitamin D derivatives by using a less expensive material. That is, the present invention provides a compound which is synthesized by using carvone as a starting material and which is represented by the following formulae.

专利号:US-2006106242-A1
优先权日:2003-02-25
标 题 :Novel intermediates for synthesis of vitamin d derivatives

专利号:US-2007135526-A1
优先权日:2004-07-07
标 题 :Synthesis of (1)-beta-elemene, (-)-beta-elemenal, (-)-beta-elemenol, (-)-beta-elemene fluoride and their analogues, intermediates, and composition and uses thereof