CAS: 79241-46-6; Fluazifop-P-Butyl

该化合物是属于丙氧基苯丙胺(AOPP)类的选择性抗除草剂,对包括大豆,棉花和甜菜在内的长叶麻作物中的草杂草特别有效,活性成分抑制乙酰CoA 碳酸酶(ACCase),干扰易感染植物中的脂肪酸合成.Fluazifop-P-butyl在低应用率下表现出高效力,确保最小的环境影响.其系统性行动确保了目标杂草内彻底迁移,导致一致控制.化合物的形成是为了稳定并符合综合虫害管理系统(IPM),特别是因其选择性,作物安全和抗药性管理潜力在除草剂轮换方案中受到重视.

结构式图片

欧盟法规

ECHA物质ECHA物质化妆品禁用物质清单C&L通报REACH预注册

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2-fluoro-5-(trifluoromethyl)pyridine (R)-2-(4-hydroxyphenoxy)propionic acid butan-1-ol

合成工艺路线路线简述

  • 合成目标产物 Fluazifop-P-Butyl 主要起始原料 2-Fluoro-5-Trifluoromethylpyridine And (R)-(+)-2-(4-Hydroxyphenoxy)Propionic Acid And 1-Butanol
  • 139218-75-0 + 96025-50-2 = 79241-46-6
    反应条件:1.1 Reagents: Potassium Carbonate Solvents: Dimethylformamide; Rt -> 90 °C1.2 85 - 90 °C; 7 H,85 - 90 °C
    标题:Synthesis Of (2R)-2-[4-[[5-(Trifluoromethyl)-2-Pyridinyl]Oxy]Phenoxy]Propanoic Acid Butyl Ester [(+)-Fluazifop Butyl]
    作者:Li,Ruijun; Bai,Yanhai; Shi,Ben; Xiao,Pengfei
    参考文献:Nongyao 日期:2007 卷标:46(5) 页码:305-306]

    69045-82-5 + 71-36-3 + 94050-90-5 = 79241-46-6
    反应条件:1.1 Reagents: Tripotassium Phosphate Catalysts: Tetrabutylammonium Iodide Solvents: Dimethylformamide; 2 H,50 - 60 °C; 60 °C -> 5 °C1.2 Reagents: Cyanuric Chloride; 10 Min,5 °C; 1 H,25 °C1.3 3 H,Rt1.4 Reagents: Sodium Hydroxide Solvents: Water; 10 Min,Ph 8,0 - 5 °C
    标题:A New Method For One-Pot Synthesis Of Aryloxyphenoxypropionate Herbicides Using 2,4,6-Trichloro-1,3,5-Triazine And (N-Bu)4Ni As A Homogeneous Catalyst
    作者:Kalhor,Mehdi; Dadras,Akbar; Mobinikhaledi,Akbar; Tajik,Hassan
    参考文献:Journal Of The Chilean Chemical Society 日期:2011 卷标:56(4) 页码:833-836
2-氟-5-三氟甲基吡啶,(R)-(+)-2-(4-羟基苯氧基)丙酸,正丁醇置于potassium Phosphate,四丁基碘化铵,三聚氯氰体系中,用 N,N-二甲基甲酰胺 作为反应溶剂,化学反应 3.17H,以81%的收率获得产物精吡氟禾草灵
参考文献:A New Method For One-Pot Synthesis Of Aryloxyphenoxypropionate Herbicides Using 2,4,6-Trichloro-1,3,5-Triazine And (N-Bu)4Ni As A Homogeneous Catalyst
标题:A New Method For One-Pot Synthesis Of Aryloxyphenoxypropionate Herbicides Using 2,4,6-Trichloro-1,3,5-Triazine And (N-Bu)4Ni As A Homogeneous Catalyst
摘要:The One-Pot Reaction Of Halo-Heterocycle,(R)-4-Hydroxyphenoxy Propionic Acid And An Alcohol,Amine Or Sulfonamide Is Described As An Efficient Method For The Synthesis Of Aryloxyphenoxy Propionate Hrerbicides By Using 2,4,6-Trichloro-1,3,5-Triazine In The Presence Of (Bu-N)(4)Ni,As A Homogeneous Catalyst Under Mild Conditions. The Present Procedure Offers Several Advantages,Such As Good Yields,Short Reaction Times And Easy Workup.
DOI:10.4067/s0717-97072011000400002

海关参考信息

专利信息


专利号:US-11919928-B2
优先权日:2016-03-16
标题 :Method for producing dihydrotentoxin
发明人:KUBO TAKASHI; MACHIDA MASAYUKI; FUJIOKA TOMONORI; YAMAGUCHI Shigenari; KAWAI KIYOSHI
权利人:KUMIAI CHEMICAL INDUSTRY CO
摘要:An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.

专利号:US-2021386068-A1
优先权日:2018-11-07
标题 :Compositions comprising pyridine carboxylate herbicides and very long chain fatty acid (vlcfa) synthesis inhibitor herbicides
发明人:KISTER JEREMY; SATCHIVI NORBERT M
权利人:CORTEVA AGRISCIENCE LLC
摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a VLCFA synthesis inhibitor herbicide. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof, and (b) a VLCFA synthesis inhibitor herbicide.

专利号:US-2021352899-A1
优先权日:2018-11-07
标题 :Compositions comprising pyridine carboxylate herbicides and fatty acid and lipid synthesis inhibitor herbicides
发明人:KISTER JEREMY; SATCHIVI NORBERT M
权利人:CORTEVA AGRISCIENCE LLC
摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof.

专利号:ES-2717283-T3
优先权日:2012-07-24
标 题:Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6- (4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylic acid or a derivative thereof and herbicides inhibitors of VLCFA synthesis and synthesis of fatty acids / lipids

专利号:TW-I655905-B
优先权日:2012-07-24
标题 :Contains 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylic acid or a derivative thereof and very long chain fatty acid (VLCFA) Synthesis of herbicidal compositions with fatty acid/fat synthesis inhibiting herbicides

专利号:US-9644469-B2
优先权日:2012-07-24
标题 :Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylic acid or a derivative thereof and VLCFA and lipid synthesis inhibiting herbicides
发明人:YERKES CARLA N; MANN RICHARD K; SHIRAISHI IKUO; YANAGIYAMA SHINGO; SATCHIVI NORBERT M
权利人:DOW AGROSCIENCES LLC
摘要:A synergistic herbicidal composition containing (a) a compound of formula (I): n nor an agriculturally acceptable salt or ester thereof and (b) VLCFA and fatty acid/lipid synthesis inhibiting herbicides, including but not limited to, acetochlor, alachlor, anilofos, benfuresate, cafenstrole, dimethenamid-P, fentrazamide, indanofan, flufenacet, mefenacet, s-metolachlor, molinate, pethoxamid, pretilachlor, prosulfocarb, pyroxasulfone, thenylchlor and thiobencarb, or a salt or ester thereof, provide synergistic weed control of undesirable vegetation in direct-seeded, water-seeded and transplanted rice, cereals, wheat, barley, oats, rye, sorghum, corn or maize, sugarcane, sunflower, oilseed rape, canola, sugar beet, soybean, cotton, pineapple, pastures, grasslands, rangelands, fallowland, turf, tree and vine orchards, aquatics, plantation crops, vegetables, industrial vegetation management (IVM) or rights-of-way (ROW).
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合成参考文献


摘要:Farm Chemicals Handbook., -(C150), 1991
摘要:Defense des Vegetaux., 39(235)(24), 1985
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