CAS: 104-65-4; Cinnamyl Formate

相似化合物

103-54-8 103-36-6 4192-77-2

上下游产品

cinnamyl acetate sodium formate cinnamyl chloride trimethylsilyl cinnamyl ether 3-Phenylpropenol 2-Benzylpyridine

甲酸甲酯,肉桂醇置于双(三甲基硅烷基)氨基钾,1,3-双(2,4,6-三甲基苯基)氯化咪唑体系中,用 甲苯 用作溶剂,化学反应 16.0H,以85%的收率获得甲酸桂酯
参考文献:N-杂环碳烯催化的甲酰基化
标题:N-杂环碳烯催化的甲酰基化
摘要:专用于赫伯特.迈尔教授在他70的庆祝日生日. 抽象的 已开发出n杂环卡宾(nhc)催化的甲酰基化反应,可将1°,2°和3°的醇转化为相应的甲酸酯.该反应使用低催化剂负载量和甲酸甲酯作为甲酰基转移试剂.反应的范围很广,据报道有23个实例收率很高(59-96%).该反应对常见的氮和氧保护基不敏感,并且可以在许多杂环的存在下完成. 已开发出n杂环卡宾(nhc)催化的甲酰基化反应,可将1°,2°和3°的醇转化为相应的甲酸酯.该反应使用低催化剂负载量和甲酸甲酯作为甲酰基转移试剂.反应的范围很广,据报道有23个实例收率很高(59-96%).该反应对常见的氮和氧保护基不敏感,并且可以在许多杂环的存在下完成.
Doi:10.1055/s-0036-1588449

专利信息

专利号:WO-03031376-A1
优先权日:2001-10-12
标 题 :Solid phase synthesis of substituted 1,5-benzodiazepine-2-one and 1,5-benzothiazepine-2-one
发明人：MORTON GEORGE C; SALVINO JOSEPH M; LABAUDINIERE RICHARD F; HERPIN TIMOTHY F
权利人:AVENTIS PHARMA INC; MORTON GEORGE C; SALVINO JOSEPH M; LABAUDINIERE RICHARD F; HERPIN TIMOTHY F
摘要:A solid phase synthetic method for making substituted 1,5-benzodiazepine-2-one or 1,5-benzothiazepine-2-one. The method is useful for synthesis of large numbers of compounds through automated parallel synthesis or combinatorial library generation and is thus important to rapid discovery or new therapeutic agents containing the base structure of 1,5-benzodiazepine-2-one or 1,5-benzothiazepine-2-one.

专利号:US-7138526-B1
优先权日:1999-06-15
标 题 :Solid phase synthesis of n,n-disubstituted diazacycloalkylcarboxy derivatives
发明人：HERPIN TIMOTHY F; MORTON GEORGE C; SALVINO JOSEPH M
权利人:AVENTIS PHARMA INC
摘要:A method for the solid phase synthesis of N,N-disubstituted diazacycloalkylcarboxy derivatives of general formula (I) and (II) is claimed. Examples include piperazine-2-carboxamide. The method is applicable to the synthesis or large combinatorial libraries

专利号:US-5215997-A
优先权日:1985-09-11
标题:Synthesis of beta-lactam compounds
发明人：HUNGERBUEHLER ERNST; KALVODA JAROSLAV
权利人:CIBA GEIGY CORP
摘要:The invention relates to an improved process for the preparation of compounds of formula ##STR1## or salts thereof, starting from compounds of formulae ##STR2## via compounds of formulae ##STR3## in which compounds R 1 is hydrogen or lower alkyl, R 2 is an organic radical which may carry a functional group which may be protected by a customary protective group R 2 o , R 3 is hydrogen or a customary carboxyl protective group R 3 o , W is a group which can be replaced by a thiocarboxylic acid radical of formula III, and Z is oxygen or sulfur.

专利号:US-2005215801-A1
优先权日:2002-06-28
标 题 :Process for preparation of optically active 1-substituted amino-2,3-epoxypropanes, intermediates for synthesis thereof and process for preparation of the intermediates
发明人：KITAJIMA KUMI; NAGASHIMA NOBUO
权利人:KITAJIMA KUMI; NAGASHIMA NOBUO
摘要:The present invention provides an industrial process for effectively and advantageously preparing optically active 1-substituted amino-2,3-epoxypropanes useful as intermediates for preparing agricultural chemicals and medical products from optically active 1-substituted amino-2,3-propanediols used as raw materials. The present invention also provides useful intermediates. Specifically, an optically active 1-substituted amino-2,3-propanediol (1) is reacted with an orthoacid ester (2) or thionyl chloride (3) to produce a cyclic optically active compound (4), and then a compound (5) containing a halogen atom is prepared by reaction with a ring-opening reaction agent having an ability to introduce a halogen atom X. Finally, an optical active 1-substituted amino-2,3-epoxypropane is prepared by ring-closure reaction in the presence of a base.

专利号:US-2008058528-A1
优先权日:2006-07-20
标题 :Synthesis of (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile

专利号:EP-1200824-B1
优先权日:1999-06-15
标题:Solid phase synthesis of n,n-disubstituted diazacycloalkylcarboxy derivatives