CAS: 141179-72-8; 4-Fluoro-2-(Trifluoromethyl)Benzoic Acid

相似化合物

194853-86-6 220227-29-2 90176-80-0

上下游产品

CAS号401-80-9 间氟三氟甲苯 | CAS号189807-21-4 4-氟-2-(三氟甲基)苯甲酰氯 | CAS号267242-09-1 4-氰基-2-三氟甲基苯甲酸 | CAS号220141-23-1 4-氟-2-(三氟甲基)苯甲酸甲酯

二氧化碳,2-溴-5-氟三氟甲苯置于碘,Magnesium体系中,用 四氢呋喃 用作溶剂,化学反应 3.0H,以90%的收率获得4-氟-2-(三氟甲基)苯甲酸
参考文献:一种4-氨基-2-三氟甲基苯腈的制备方法
标题:一种4-氨基-2-三氟甲基苯腈的制备方法
摘要:本发明涉及化工技术领域,具体涉及一种4‑氨基‑2‑三氟甲基苯腈的制备方法包括如下步骤:2‑溴‑5‑氟三氟甲苯经过格氏化反应后,通入二氧化碳,再进行水解得到4‑氟‑2‑三氟甲基苯甲酸;将4‑氟‑2‑三氟甲基苯甲酸加入压力釜中,通入液氨在催化剂作用下反应生成4‑氨基‑2‑三氟甲基苯甲酰胺;将4‑氨基‑2‑三氟甲基苯甲酰胺与脱水剂一起加热脱水生成4‑氨基‑2‑三氟甲基苯腈.本发明提供的4‑氨基‑2‑三氟甲基苯腈的制备方法不使用剧毒的氰化亚铜,减少了生产的安全风险,三废中不含氰根离子和大量铜离子,更容易处理,对环境危害小.

专利信息

专利号:CN-115677472-B
优先权日:2022-11-04
标题 :Synthesis method of drug intermediate and application of drug intermediate in synthesis of penconazole

专利号:US-9217012-B2
优先权日:2009-04-08
标题 :Inhibitors of protein tyrosine phosphatases
发明人：ZHANG ZHONG-YIN; ZHANG SHENG
权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

专利号:HU-E035391-T2
优先权日:2012-06-11
标 题 :Process for the preparation of 4,4,7-trifluoro-1,2,3,4-tetrahydro-5H-1-benzazepine compound and intermediate of synthesis