专利号:US-2005170281-A1 优先权日:2002-06-21 标题:Method of cleaving labile functional groups from chemical compounds 发明人:STENGELE KLAUS-PETER 摘要:The present invention provides a method of cleaving labile functional groups from molecules by exposure to electromagnetic radiation in which the molecules are contacted with a chemical compound whose triplet state is energetically higher than the triplet state of the labile functional group and are then exposed to electromagnetic radiation, with the labile functional group and the suitable chemical compound having different absorption maxima for electromagnetic radiation. Further, the invention provides a method of manufacturing DNA chips by spatially addressed, light-controlled nucleotide synthesis on solid substrates. In addition, the present invention provides a chemical composition comprising a molecule with a labile functional group and a chemical compound whose triplet state is higher than the triplet state of the labile functional group, with the labile functional group and the chemical compound having different absorption maxima for electromagnetic radiation, and describes the use of the chemical composition in the manufacture of DNA chips.
专利号:US-7598019-B2 优先权日:2002-03-04 标 题:Method for cleavage of labile functional groups from chemical compounds 发明人:STEINER ULRICH; WOLL DOMINIK; WALBERT STEFAN 权利人:UNI KONSTANZ 摘要:The present invention provides a method for cleavage of labile functional groups from molecules by the action of electromagnetic radiation, wherein the molecules are contacted with a chemical compound whose triplet state is energetically higher than the triplet state of the labile functional group, and are subsequently exposed to electromagnetic radiation. Further, the invention provides a method for preparing DNA chips by spatially addressed, light-controlled nucleotide synthesis on solid substrates, said method comprising the following steps: a) reacting the unprotected terminal 3′ or 5′ hydroxy group of a nucleoside and/or of a nucleotide arranged on the solid substrate under usual conditions with a photolabile protective group and optionally purifying the reaction product, b) applying a solution, suspension or dispersion of a chemical compound, whose triplet state is energetically higher than the triplet state of the photolabile protective group, to the surface of the carrier, said surface comprising the nucleotides and/or nucleosides modified in step a): c) irradiating, in a spatially selective manner, the surface of the carrier treated in step b) with electromagnetic radiation in the UV/VIS range with simultaneous, spatially selective release of a reactive OH group and subsequently reacting it with a nucleoside and/or nucleotide comprising a 5′ or 3′OH group, said nucleoside and/or nucleotide being further provided with a photolabile functional group. Moreover, the present invention provides a chemical composition comprising a molecule having a labile functional group, as well as a chemical compound whose triplet state is higher than the triplet state of the labile functional group, and it describes the use of the chemical composition for preparing DNA chips.
专利号:US-12084554-B2 优先权日:2017-04-10 标 题 :Polyphenylenes, methods, and uses thereof 发明人:HOLDCROFT STEVEN; SKALSKI THOMAS J G; ADAMSKI MICHAEL; BRITTON BENJAMIN; PECKHAM TIMOTHY J 权利人:UNIV FRASER SIMON 摘要:Described herein are anionic phenylene oligomers and polymers, and devices including these materials. The oligomers and polymers can be prepared in a convenient and well-controlled manner, and can be used in cation exchange membranes. Also described is the controlled synthesis of anionic phenylene monomers and their use in synthesizing anionic oligomers and polymers, with precise control of the position and number of anionic groups.
专利号:US-6416861-B1 优先权日:1999-02-16 标题 :Organosilicon compounds and uses thereof 发明人:LEE YOUNGHEE; SILVERMAN RICHARD B 权利人:UNIV NORTHWESTERN 摘要:A compound of the formula: n and a resin-bound compound of the formula: n and their use in combinatorial chemistry and in the synthesis of compounds comprising at least one aromatic moiety is described, where R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , L 1 , P, Ar 1 , and X are as herein defined.
专利号:US-3651151-A 优先权日:1964-12-04 标 题 :Preparation of polyphenyl ether from dihydric phenols 发明人:BRIDGER ROBERT F; KINNEY ROBERT E; WILILAMS ALBERT L 权利人:MOBIL OIL CORP 摘要:DIHYDRIC PHENOIS CAN BE USED DIRECTLY IN THE ULLMANN ETHER SYNTHESIS BY USING A COPPER SALT CATALYST AND AN AMINE SOLVENT THAT DISSOLVES THE CATALYST BY FORMING COORDINATE COVALENT BONDS WITH COPPER IONS.
专利号:CN-115093308-B 优先权日:2022-07-06 标题 :A kind of synthesis method of 1-bromo-4-phenylnaphthalene
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