2-磺基苯甲酸酐,间甲酚 以15%的收率获得间甲酚紫 参考文献:Solvent-Free Synthesis Of Sulfonephthaleins,Sulfonefluoresceins And Fluoresceins Under Microwave Irradiation 标题:Solvent-Free Synthesis Of Sulfonephthaleins,Sulfonefluoresceins And Fluoresceins Under Microwave Irradiation 摘要:报道了一种高效的无溶剂合成磺酮邻苯二甲酸酯,磺酮荧光素和荧光素的方法,在微波辐射下进行. Doi:10.1135/cccc20021779
专利号:CN-114989235-A 优先权日:2015-09-28 标题:Design and synthesis of nucleotides based on novel disulfide linkers for use as reversible terminators for DNA sequencing by synthesis
专利号:CN-108779138-B 优先权日:2015-09-28 标题 :Design and synthesis of novel disulfide linker-based nucleotides for use as reversible terminators for DNA sequencing by synthesis
专利号:US-9976179-B2 优先权日:2011-03-30 标 题 :Nucleic acid sequencing technique using a pH-sensing agent 发明人:HAUSHALTER ROBERT C 权利人:PARALLEL SYNTHESIS TECH; PARALLEL SYNTHESIS TECH INC 摘要:The invention relates to a composition, method and apparatus for determining the sequence of a nucleic acid strand utilizing a pH-sensing agent.
专利号:US-11952324-B2 优先权日:2017-08-04 标 题 :Amidoamine synthesis, methods to track the reaction process 发明人:KHRAMOV DIMITRI M; CHEN YIYAN; OKHRIMENKO ALBERT 权利人:MI LLC; SCHLUMBERGER TECHNOLOGY CORP 摘要:Methods may include quantifying the concentration of residual free amine and/or free carboxylic acid in a product mixture prepared from a reaction of a multireactive species and a fatty reagent; verifying that the concentration for the free amine and/or free acid in the product mixture is within an acceptable threshold for a given application; and combining the product mixture with one or more wellbore fluid components to generate the wellbore fluid. In another aspect, methods may include including reacting the multireactive species and a fatty reactant to generate a product mixture; quantifying the concentration of residual free amine and/or free carboxylic acid in the product mixture; verifying that the concentration for the free amine and/or free acid in the product mixture is within an acceptable threshold for a given application; and collecting the product mixture.
专利号:WO-2024097977-A1 优先权日:2022-11-04 标题:Silk nanoparticle synthesis: tuning size, dispersity, and surface chemistry for drug delivery 发明人:SHAIDANI SAWNAZ; FALCUCCI THOMAS; FOSTER OLIVIA; SAHOO JUGAL KISHORE; HASTURK ONUR; KAPLAN DAVID L; JACOBUS CHARLOTTE S 权利人:TUFTS COLLEGE 摘要:Methods disclosed herein relate to generating silk nanoparticles with a low polydispersity index (PDI). Methods include adding a silk solution dropwise into a volatile solvent that is miscible with water, thereby forming a precipitate-bearing solution and applying shear forces to the precipitate-bearing solution for a length of time sufficient to achieve evaporation of at least 95% of the volatile solvent, thereby producing a population of silk fibroin nanoparticles in water having a polydispersity index (PDI) of 0.35 or less, including but not limited to, a PDI of 0.330 or less, 0.325 or less, 0.315 or less, 0.310 or less, 0.30 or less, 0.275 or less, 0.250 or less, 0.225 or less, or 0.200 or less. Parameters related to silk fibroin molecular weight, silk fibroin concentration, shear force application, and temperature may all be modified to achieve silk nanoparticles of a particular size exhibiting particular PDIs.
专利号:US-2020392562-A1 优先权日:2017-12-22 标 题:Polymerase chain reaction composition comprising amines 发明人:Matjosaitis Karolis; RIMKUS RENALDAS; VANAGAS LAURYNAS; SUKACKAITE RASA; Valinskyte Skaiste; ELIJOSIUTE EDITA; STREPETKAITE DOVILE 权利人:THERMO FISHER SCIENTIFIC BALTICS UAB 摘要:Compositions, methods, and kits comprising amines are described for use in nucleic acid synthesis. In some embodiments, amines improve nucleic acid synthesis product yield or tolerance to inhibitors of nucleic acid synthesis.
1: Zhang Y, Lim LT. Inkjet-printed CO(2) colorimetric indicators. Talanta. 2016 Dec 1;161:105-113. doi: 10.1016/j.talanta.2016.08.014. Epub 2016 Aug 20. doi: 10.1021/es300491s. Epub 2012 Apr 11. Erratum in: Environ Sci Technol. 2015 May 5;49(9):5841. 3: Mitchell RP, Baumgartner JC, Sedgley CM. Apical extrusion of sodium hypochlorite using different root canal irrigation systems. J Endod. 2011 Dec;37(12):1677-81. doi: 10.1016/j.joen.2011.09.004. Epub 2011 Oct 22.
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