CAS: 3481-09-2; N-Chlorophthalimide

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CAS号1074-82-4 邻苯二甲酰亚胺钾盐 | CAS号33081-78-6 邻苯二甲酰亚胺钠盐 | CAS号507-40-4 次氨酸叔丁基酯 | CAS号67-66-3 氯仿 | CAS号7782-50-5 氯气 | CAS号7732-18-5 水 | CAS号13898-47-0 chlorous acid | CAS号50593-68-5 3-氯-6-硝基吲唑 | CAS号87-41-2 苯酞 | CAS号27722-45-8 N-Tosylphthalimide | CAS号118-92-3 邻氨基苯甲酸 | CAS号298-96-4 2,3,5-三苯基氯化四氮唑 | CAS号71098-88-9 N-苯硒基邻苯二甲酰胺 | CAS号165669-14-7 3-氯7-硝基-1H-吲哚 | CAS号7143-42-2 methyl 2-(metho... | CAS号7764-29-6 N,N′-硫代酞酰亚胺

Potassium Phtalimide置于溶剂黄146体系中,用 水 作为反应溶剂,以92.5%的收率获得产物n-氯代酞酰亚胺
参考文献:Process For Preparing N-Chlorophthalimide
标题:Process For Preparing N-Chlorophthalimide
摘要:N-氯代邻酰亚胺是通过在卤代脂肪烃存在下,在大约-10oc到+40oc的温度下,在实质上非水条件下接触邻酰亚胺的碱金属盐和氯来制备的.

专利信息

专利号:WO-2025078335-A1
优先权日:2023-10-09
标 题 :Processes for the preparation of deucravacitinib
发明人：ETAYO PÉREZ PABLO; PUJOL OLLÉ XAVIER; MOLINA NIETO JUAN
权利人:FARMHISPANIA GROUP S L
摘要:The invention relates to processes for the preparation of deucravacitinib of formula (XI), or a pharmaceutically acceptable salt thereof. It also relates to intermediates of formula (V') and (V'') as defined herein useful in the synthesis of this molecule.

专利号:US-2009198084-A1
优先权日:2006-05-02
标题:Process for the deprotection of protected amines
发明人：ALSTERS PAULUS LAMBERTUS; VERKADE JORGE MERIJN MATHIEU; QUAEDFLIEG PETER JAN LEONARD MARIO; RUTJES FLORIS PETRUS JOHANNES
权利人:ALSTERS PAULUS LAMBERTUS; VERKADE JORGE MERIJN MATHIEU; QUAEDFLIEG PETER JAN LEONARD MARIO; RUTJES FLORIS PETRUS JOHANNES
摘要:The present invention relates to a process for the deprotection of protected amine compounds, wherein the protected amine compound is contacted with an electrophilic oxidating agent that is optionally formed in situ, said electrophilic oxidating agent being selected from the group of I 2 , Br 2 , Cl 2 and compounds comprising a halogen atom having a formal oxidation state of 1+, 3+, 5+ or 7+, provided that the electrophilic oxidating agent is not iodobenzene diacetate. The process can be conveniently employed in the synthesis of 1,3-amino alcohols, β-amino acids and heterocyclic compounds, in particular β-amino acids.

专利号:US-6096900-A
优先权日:1999-05-07
标 题 :Solventless preparation of phthalimides
发明人：NICK ROBERT JOSEPH; NELSON MARK ERIK; CARINGI JOSEPH JOHN; WILLIAMS DREW ELLIOT
权利人:GEN ELECTRIC
摘要:A method for the solventless synthesis of a phthalimide or phthalimide mixture is provided comprising contacting at least one amine reactant and at least one anhydride reactant in a solventless environment at a first temperature sufficient to allow the reactants to at least partially condense; and increasing the temperature to a second temperature sufficient to melt the reaction mixture, thereby allowing the reaction to go essentially to completion and form the reaction product.

专利号:WO-0146142-A1
优先权日:1999-12-20
标题:A process for the regioselective synthesis of 2,2-dialkyl-4-substituted piperidines
发明人：HEATH PERRY CLARK
权利人:LILLY CO ELI; HEATH PERRY CLARK
摘要:The present invention provides a process for preparing a compound of formula (I): wherein R?1 and R2¿ each independently represent C¿1?-C4 alkyl; and X represents an alkyl, alkenyl, cycloalkyl, aryl, substituted aryl, heterocycle, or substituted heterocycle, comprising treating a compound of formula (II): wherein Q represents Cl or Br, with a suitable base followed by addition of a suitable Lewis acid and addition of a compound of formula R?-M+¿ wherein M+ is a suitable cation.

专利号:US-2022056025-A1
优先权日:2018-09-25
标 题:Synthesis of pyrido[2,3-d]pyrimidin-7(8h)-ones
发明人：BROWN ADAM ROSS; DESROSIERS JEAN-NICOLAS; DUAN SHENGQUAN; HAWKINS JOEL MICHAEL; HAYWARD CHERYL MYERS; MALONEY MARK THOMAS; MONFETTE SEBASTIEN; PERFECT HAHDI HAKIMIOUN; WIDLICKA DANIEL WILLIAM
权利人:PFIZER
摘要:This invention relates to novel methods to prepare substituted pyrido[2,3-d]pyrimidin-7(8H)-ones, and salts and stereoisomers thereof, as well as intermediates useful for the preparation of such compounds.

专利号:US-2022056053-A1
优先权日:2019-05-06
标 题:Synthesis of crac channel inhibitors
发明人：STAUDERMAN KENNETH A; DUNN MICHAEL; WHITTEN JEFFREY P; ROGERS EVAN
权利人:CALCIMEDICA INC
摘要:A convergent synthetic method for the production of CRAC channel inhibitors is described herein. The synthetic method provides a method for producing highly pure CRAC channel inhibitors for clinical testing.