CAS: 4334-88-7; (4-Ethoxycarbonylphenyl)Boronic Acid

上下游产品

CAS号14047-29-1 4-羧基苯硼酸 | CAS号7664-93-9 硫酸 | CAS号51934-41-9 对碘苯甲酸乙酯 | CAS号64-17-5 乙醇 | CAS号47230-38-6 4,4'-联苯二甲酸二乙酯 | CAS号119838-61-8 4-乙酰基-[1,1-联苯]-... | CAS号6242-99-5 Ethyl 4'-nitro-... | CAS号6301-56-0 [1,1'-联苯]-4-甲酸乙酯 | CAS号732-80-9 4'-甲氧基-4-连苯基羧酸乙酯 | CAS号583-02-8 4-(三氟甲基)苯甲酸乙酯 | CAS号86718-07-2 4-(1-咪唑基)苯甲酸乙酯 | CAS号3516-89-0 Benzeneacetic a... | CAS号120-47-8 尼泊金乙酯 | CAS号175153-33-0 ethyl 4-(iMidaz...

苯佐卡因置于盐酸,Sodium Nitrite,四羟基二硼体系中,用 甲醇,水 作为反应溶剂,化学反应 1.5H,以65%的收率获得产物4-乙氧羰基苯硼酸
参考文献:Methanol-Promoted Borylation Of Arylamines: A Simple And Green Synthetic Method To Arylboronic Acids And Arylboronates
标题:Methanol-Promoted Borylation Of Arylamines: A Simple And Green Synthetic Method To Arylboronic Acids And Arylboronates
摘要:A Sandmeyer Borylation Of Arylamines Via A Sn2Ar Pathway Promoted By Methanol With Sodium Nitrite And Hydrochloric Acid As Diazotization Agent Has Been Developed,Which Provide A Simple And Green Synthetic Method To Arylboronic Acids And Arylboronates.
DOI:10.1055/s-0033-1339118

专利信息

专利号:JP-6038111-B2
优先权日:2014-12-27
标 题:2,6-Dichloro-8-iodo-7-deazapurine for the synthesis of polysubstituted 7-deazapurine derivatives

专利号:US-9938258-B2
优先权日:2012-11-29
标 题:Substituted 2,3-dihydrobenzofuranyl compounds and uses thereof
发明人：BALOGLU ERKAN; SHECHTER SHARON; SHACHAM SHARON; MCCAULEY DILARA; SENAPEDIS WILLIAM; GOLAN GALI; KALID ORI
权利人:KARYOPHARM THERAPEUTICS INC
摘要:The invention generally relates to substituted 2,3-dihydrobenzofuranyl compounds, and more particularly to a compound represented by Structural Formula I: n nor a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of Structural Formula I, or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment of cancer (e.g., mantle cell lymphoma), and other diseases and disorders.

专利号:WO-2009055631-A1
优先权日:2007-10-25
标 题 :Calcilytic compounds
发明人：CASILLAS LINDA N; RAMANJULU JOSHI M; MARQUIS ROBERT W JR
权利人:SMITHKLINE BEECHAM CORP; CASILLAS LINDA N; RAMANJULU JOSHI M; MARQUIS ROBERT W JR
摘要:Novel calcilytic compounds, pharmaceutical compositions, pharmaceutical combinations, methods of synthesis and methods of using them are provided.

专利号:US-8178559-B2
优先权日:2004-12-30
标 题:Organic compounds
发明人：BREITENSTEIN WERNER; EHARA TAKERU; EHRHARDT CLAUS; GROSCHE PHILIPP; HITOMI YUKO; IWAKI YUKI; KANAZAWA TAKANORI; KONISHI KAZUHIDE; MAIBAUM JUERGEN KLAUS; MASUYA KEIICHI; IWASAKI ATSUKO; OSTERMANN NILS; SUZUKI MASAKI; TOYAO ATSUSHI; YOKOKAWA FUMIAKI
权利人:BREITENSTEIN WERNER; EHARA TAKERU; EHRHARDT CLAUS; GROSCHE PHILIPP; HITOMI YUKO; IWAKI YUKI; KANAZAWA TAKANORI; KONISHI KAZUHIDE; MAIBAUM JUERGEN KLAUS; MASUYA KEIICHI; IWASAKI ATSUKO; OSTERMANN NILS; SUZUKI MASAKI; TOYAO ATSUSHI; YOKOKAWA FUMIAKI; NOVARTIS AG
摘要:3,4-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,4-substituted piperidine compound, and/or a method of treatment comprising administering a 3,4substituted piperidine compound, a method for the manufacture of a 3,4-substituted piperidine compound, and novel intermediates and partial steps for their synthesis are disclosed. The 3,4-disubstituted piperidine compounds have the formula (I), wherein the symbols have the meanings defined in the specification.

专利号:RU-2197482-C2
优先权日:1997-04-22
标 题 :Substituted phenyl derivatives, method of their synthesis, pharmaceutical composition comprising thereof and method of treatment (variants)

专利号:RU-2150470-C1
优先权日:1994-04-19
标题 :Bicyclic thiophene derivatives, method of their synthesis and composition based on thereof