CAS: 7786-30-3; Magnesium Chloride

相似化合物

7791-18-6 7791-18-6 7791-18-6

上下游产品

ethylmagnesium chloride methyltrichlorogermane isopropylmagnesium chloride triethylaluminummagnesium dipropionate magnesium formate diethyl 2-(2-methyl-3-nitrobenzoyl)malonate strontium chloride

氯化钠 反应生成 氯化镁
参考文献:Maksin,V. I.;Chernova,L. G.;Lampeka,E. G.
标题:Maksin,V. I.;Chernova,L. G.;Lampeka,E. G.

专利信息

专利号:WO-2024185734-A1
优先权日:2023-03-03
标 题:Polyphosphorylated nucleoside, phosphate-activated nucleotide used for synthesis of polyphosphorylated nucleoside and method for synthesis of same, and method for synthesis of polyphosphorylated nucleoside using phosphate-activated nucleotide
发明人：KATAOKA MASANORI; FUKUI CHIHARU; TSUJI YOHEI; FUJIMURA Kazuma
权利人:NATIAS INC
摘要:The present invention provides: a polyphosphorylated nucleoside which has a structure represented by formula (I) and can be efficiently produced by a short process and a simple operation with use of a less expensive material; a phosphate-activated nucleotide which is used for the synthesis of the polyphosphorylated nucleoside and a method for the synthesis of this phosphate-activated nucleotide; and a method for the synthesis of a polyphosphorylated nucleoside using a phosphate-activated nucleotide. In the formula, B represents a protected or unprotected, natural or artificial nucleoside base; R 1 , R 2 , R 4 and R 5 each represent H or an alkyl group or the like, and R 1 , R 2 , R 4 and R 5 may be the same as or different from each other; X and Y each represents H, OH, OCH 3 or the like; h represents an integer of 1 to 3; p, n, m and q each represent 0 or an integer, and p, n, m and q are in no particular order; and (p + n + m + q) is an integer of 0 to 5,000.

专利号:US-11661406-B2
优先权日:2018-08-13
标 题 :Method for producing intermediate useful for synthesis of SGLT inhibitor
发明人：LI QING RI; YOON HEE KYOON
权利人:DAEWOONG PHARMACEUTICAL CO LTD
摘要:A method of preparing an intermediate useful for the synthesis of a diphenylmethane derivative that can be used as an SGLT inhibitor is described. A method of synthesizing a compound of Formula 7 can address problems of existing synthesis processes requiring the synthesis of the Grignard reagent and management of related substances. In addition, the method can minimize the generation of related substances, and thus does not require reprocessing of reaction products, thereby simplifying the process. Accordingly, the production yield of a diphenylmethane derivative can be maximized.

专利号:US-2025257380-A1
优先权日:2023-01-31
标 题:Method for template-free de novo synthesis of long-chain nucleic acid, and use thereof
发明人：XU CHENG; LIU YUANXIAO
权利人:SHANGHAI TYPING BIOSCIENCE CO LTD
摘要:The present application relates to the fields of molecular biology and biotechnology, and in particular to a method for template-free de novo synthesis of a long-chain nucleic acid, including the following steps: S1, synthesis of double-stranded oligonucleotides; and S2, combination and ligation of the double-stranded oligonucleotides to obtain a target long-chain nucleic acid. The present application achieves continuous synthesis from single nucleotides to long-chain nucleic acids by means of the combination of S1 and S2, and has the advantages of no need for templates, high accuracy, low complexity and low cost.

专利号:US-7294486-B2
优先权日:2001-09-05
标 题:Enzymatic process for the synthesis of organo-fluorine compounds
发明人：O'HAGAN DAVID; SCHAFFRATH CHRISTOPH
权利人:UNIV ST ANDREWS
摘要:There is described a process for the synthesis of a fluoronucleoside compound, said process comprising mixing a substrate and an enzyme from Streptomyces cattelya as catalyst. The process may be used to produce an 18 F labelled fluoronucleoside compound. There is also described an enzyme derived from Streptomyces cattelya which has the capacity to catalyse the synthesis of a fluoronucleoside compound.

专利号:WO-2024082909-A1
优先权日:2022-10-18
标 题:Detection method for monitoring synthesis of rna by in vitro transcription in real time
发明人：YANG GUANGYU; QIN WEITONG; LI LIANG; YANG FAN
权利人:SHANGHAI SHENDAO BIOTECHNOLOGY CO LTD; UNIV SHANGHAI JIAOTONG
摘要:A detection method for monitoring synthesis of RNA by in vitro transcription in real time, relating to the technical field of molecular biology and transcription. A DNA template suitable for in vitro transcription and a real-time fluorescent transcription system are developed, and a high-throughput, simple and sensitive RNA synthesis monitoring and quantification system is established. The DNA template/real-time fluorescent transcription system/monitoring system can be applied to synthesizing mRNA vaccines, screening RNA polymerases, analyzing promoter strength, screening drugs for inhibiting transcription, optimizing mRNA drug production process, training mRNA drug sequence AI design software and the like, and can further be applied to optimizing an in vitro transcription system, quantifying RNA polymerase activity, and optimizing sequences.

专利号:US-11066439-B2
优先权日:2016-12-10
标题 :Synthesis of liraglutide
发明人：GANGA RAMU VASANTHAKUMAR; PATIL NITIN; CHARYULU PALLE VENKATA RAGHAVENDRA; JASMINE CASTELINO ROOPA; MACHANI RAMBABU; SUVARNA DEEPA SHANKAR
权利人:BIOCON LTD
摘要:The present invention relates to the efficient solid-phase synthesis of liraglutide represented by Formula-I. The present invention relates to an efficient process for the preparation of liraglutide by sequential coupling employing solid phase approach. It involves sequential coupling of protected amino acids to prepare backbone of liraglutide and upon completion of linear sequence, synthesis was extended from lysine side chain by adding γ-glutamic acid and palmitic acid, followed by removal of protective groups, cleavage of the peptide from solid support and purification of crude liraglutide obtained. The present invention also involves the usage of inorganic salts during the coupling, wash with HOBt in DMF solution after Fmoc-deprotection step to suppress the aggregation of peptides and ensure reactions are going for completion, and thus avoid deletion sequences and improve the process yield.