CAS: 1613220-15-7; (S)-2-(4-(Piperidin-3-yl)Phenyl)-2H-Indazole-7-Carboxamide 4-Methylbenzenesulfonate Hydrate

专利信息

专利号:US-10927095-B2
优先权日:2017-08-14
标 题:Processes for the preparation of Niraparib and intermediates thereof
发明人：LUTHRA PARVEN K; VASOYA SANJAY L; PATIL BHATU T; TANEJA AMIT K; SRIVASTAV NAVEEN C; SINGH RINKU
权利人:TEVA PHARMACEUTICALS INT GMBH
摘要:The present invention relates to novel procedures and novel intermediates useful in the synthesis of Niraparib or any salt thereof.

专利号:US-2022118094-A1
优先权日:2019-02-21
标题:Synthesis of biomimetic cell wall structure
发明人：WANG YONG; SHI PENG
权利人:PENN STATE RES FOUND
摘要:The present invention relates generally to methods of generating a biomimetic cell wall (BCW) on a target surface, compositions comprising the BCW, and methods of use of the compositions, including biomedical applications of the BCW coated compositions.

专利号:US-11629137-B2
优先权日:2017-04-24
标 题:Methods of manufacturing of niraparib
发明人：STEWART ALISTAIR; TOTO ANTHONY JOSEPH; CHEN FRANK XING; WU GEORGE
权利人:TESARO INC
摘要:Disclosed herein are methods and processes of preparing niraparib and pharmaceutically acceptable salts thereof, and intermediates and their salts useful for the synthesis of niraparib.

专利号:US-2025084464-A1
优先权日:2021-09-30
标 题:Compositions and methods for synthesis and use of probes targeting nucleic acid rearrangements
发明人：WU INDIRA
权利人:GUARDANT HEALTH INC
摘要:Provided herein are methods of analyzing nucleic acids for detecting DNA rearrangements. Provided herein are also methods for determining the likelihood that a subject has a disease or condition, such as cancer.

专利号:WO-2025137620-A1
优先权日:2023-12-21
标题:Methods for high quality and high accuracy methylation sequencing
发明人：KENNEDY ANDREW
权利人:GUARDANT HEALTH INC
摘要:Provided herein are methods and compositions for calibrating one or more base calling metrics in a sequencing by synthesis reaction, and for calling at least a portion of nucleobases in a converted region of a DNA molecule using the one or more calibrated base calling metrics. Provided herein are also methods for determining the likelihood that a subject has a disease or condition, such as cancer.

专利号:EP-4409024-A1
优先权日:2021-09-30
标题:Compositions and methods for synthesis and use of probes targeting nucleic acid rearrangements