CAS: 2595-05-3; 1,2:5,6-Di-O-Isopropylidene-Alpha-D-Allofuranose

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D-Glucose置于sodium Hypochlorite,Sodium Tetrahydroborate,2,2,6,6-四甲基哌啶氧化物,磷酸,碳酸氢钠,Potassium Bromide,Zinc(II) Chloride体系中,用 水,乙酸乙酯 用作溶剂,化学反应生成1,2:5,6-二异亚丙基-Alpha-D-异呋喃糖
参考文献: Novel Process For Making Allofuranose From Glucofuranose[fr] Nouveau Procédé De Fabrication D'Allofuranose à Partir De Glucofuranose
标题: Novel Process For Making Allofuranose From Glucofuranose[fr] Nouveau Procédé De Fabrication D'Allofuranose à Partir De Glucofuranose
摘要:本发明涉及从描述和权利要求中定义的葡糖呋喃糖中制备阿洛呋喃糖.阿洛呋喃糖是合成寡核苷酸时的中间体,可用作药物.

专利信息

专利号:US-7569686-B1
优先权日:2006-01-27
标题:Compounds and methods for synthesis of bicyclic nucleic acid analogs
发明人：BHAT BALKRISHEN; XIA JIE; SETH PUNIT P; VASQUEZ GUILLERMO; MIGAWA MICHAEL T; ALLERSON CHARLES; PRAKASH THAZHA P; SWAYZE ERIC E
权利人:ISIS PHARMACEUTICALS INC
摘要:The present invention provides compounds and methods of using them for preparing bicyclic nucleosides. The bicyclic nucleosides are useful for preparing chemically modified oligomeric compounds. Oligomeric compounds comprising these bicyclic nucleosides have enhanced properties such as increased nuclease resistance.

专利号:US-9701682-B2
优先权日:2013-11-11
标题:Pyrrolo[1,2-f][1,2,4]triazines useful for treating respiratory syncitial virus infections
发明人：CLARKE MICHAEL O'NEIL HANRAHAN; DOERFFLER EDWARD; MACKMAN RICHARD L; SIEGEL DUSTIN
权利人:GILEAD SCIENCES INC
摘要:Provided herein are formulations, methods and substituted tetrahydrofuranyl-pyrrolo[1,2-f][1,2,4]triazine-4-amine compounds of Formula (I) for treating Pneumovirinae virus infections, including respiratory syncytial virus infections, as well as methods and intermediates for synthesis of tetrahydrofuranyl-pyrrolo[1,2-f][1,2,4]triazine-4-amine compounds.

专利号:US-6069238-A
优先权日:1998-09-30
标 题:Spirocyclic C-glycosides
发明人：HITCHCOCK STEPHEN ANDREW; HAMDOUCHI CHAFIQ; SANCHEZ-MARTINEZ CONCEPCION; ESTEBAN ALMUDENA RUBIO
权利人:LILLY CO ELI
摘要:An improved and a new synthetic route for the reparation of spirocyclic C-glycoside compounds having the following general structure are described. Novel derivatives of spirocyclic C-glycoside compounds are also disclosed which may be used as intermediates in the synthesis and evaluation of potential pharmaceutically active materials.