CAS: 3977-29-5; 2-Amino-6-Methylpyrimidin-4(1H)-One

相似化合物

5734-66-7 108-53-2 73576-32-6

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CAS号50-01-1 盐酸胍 | CAS号141-97-9 乙酰乙酸乙酯 | CAS号55996-28-6 2-甲氧基-4-羟基-6-甲基嘧啶 | CAS号593-85-1 碳酸胍 | CAS号113-00-8 guanidine | CAS号594-14-9 硫酸胍 | CAS号13509-52-9 1,3,6-三甲基嘧啶-2,4... | CAS号5600-21-5 2-氨基-4-氯-6-甲基嘧啶 | CAS号5424-21-5 2,4-二氯-6-甲基嘧啶 | CAS号674-82-8 双乙烯酮 | CAS号5600-21-5 2-氨基-4-氯-6-甲基嘧啶 | CAS号151587-58-5 N1-(Pivaloyloxy... | CAS号4214-85-1 2-氨基-6-甲基-5-硝基-... | CAS号18595-67-0 2-氨基-6-甲基-4-氧代-... | CAS号2829-59-6 6-甲基-5-硝基-2,4-吡啶二胺 | CAS号897030-99-8 4-氯-5-碘-6-甲基-2-嘧啶胺 | CAS号95980-02-2 7-甲基-2-苯基-咪唑并[1... | CAS号5734-71-4 2-氨基-4-溴-6-甲基嘧啶 | CAS号65996-58-9 2-氨基-3,5-二氢吡咯并[... | CAS号6307-35-3 2-氨基-5-溴-6-甲基-4-咆嘧啶

2-甲氧基-4-甲基-6-羟基嘧啶置于sodium Amide体系中,用 1,2,3,4-四氢萘 用作溶剂,化学反应 24.0H,以52%的收率获得2-氨基-4-羟基-6-甲基嘧啶
参考文献:Botta,M.; Angelis,F. De; Finizia,G.,Synthetic Communications,1985,Vol. 15,P. 27-34
标题:Botta,M.; Angelis,F. De; Finizia,G.,Synthetic Communications,1985,Vol. 15,P. 27-34

专利信息

专利号:US-6818633-B2
优先权日:2001-06-29
标题:Antiviral compounds and methods for synthesis and therapy
发明人：BALZARINI JAN M R; DE CLERCQ ERIK D A; HOLY ANTONIN
权利人:ACAD OF SCIENCE CZECH REPUBLIC; REGA STICHTING
摘要:Novel compounds are provided having formula (I)whereR1, R2, R3, R4, Z, X and * are defined herein. Also provided are antiviral methods for use and processes for synthesis of the compounds of formula (I).

专利号:US-4849513-A
优先权日:1983-12-20
标 题 :Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups
发明人：SMITH LLOYD M; FUNG STEVEN; KAISER ROBERT J
权利人:CALIFORNIA INST OF TECHN
摘要:The invention consists of compounds and methods for the synthesis of oligonucleotides which contain one or more free aliphatic amino groups attached to the sugar moieties of the nucleoside subunits. The synthetic method is versatile and general, permitting amino groups to be selectively placed at any position on oligonucleotides of any composition or length which is attainable by current DNA synthetic methods. Fluorescent dyes or other detectable moieties may be covalently attached to the amino groups to yield the corresponding modified oligonucleotide.

专利号:US-5118802-A
优先权日:1983-12-20
标 题:DNA-reporter conjugates linked via the 2' or 5'-primary amino group of the 5'-terminal nucleoside
发明人：SMITH LLOYD M; FUNG STEVEN; KAISER JR ROBERT J
权利人:CALIFORNIA INST OF TECHN
摘要:The invention consists of compounds and methods for the synthesis of oligonucleotides which contain one or more free aliphatic amino groups attached to the sugar moieties of the nucleoside subunits. The synthetic method is versatile and general, permitting amino groups to be selectively placed at any position on oligonucleotides of any composition or length which is attainable by current DNA synthetic methods. Fluorescent dyes or other detectable moieties may be covalently attached to the amino groups to yield the corresponding modified oligonucleotide.

专利号:US-5118800-A
优先权日:1983-12-20
标 题 :Oligonucleotides possessing a primary amino group in the terminal nucleotide
发明人：SMITH LLOYD M; FUNG STEVEN; KAISER JR ROBERT J
权利人:CALIFORNIA INST OF TECHN
摘要:The invention consists of compounds and methods for the synthesis of oligonucleotides which contain one or more free aliphatic amino groups attached to the sugar moieties of the nucleoside subunits. The synthetic method is versatile and general, permitting amino groups to be selectively placed at any position on oligonucleotides of any composition or length which is attainable by current DNA synthetic methods. Fluorescent dyes or other detectable moieties may be covalently attached to the amino groups to yield the corresponding modified oligonucleotide.

专利号:US-2005085492-A1
优先权日:2003-10-20
标 题:Stereoselective process for the synthesis of chiral garft compounds and intermediates
发明人：RAHMAN LEERA
权利人:AGOURON PHARMACEUTICALS MINC
摘要:The present invention describes a stereoselective preparation of derivatives and precursors of molecules having formula 1: n nMethod of preparing the compounds, intermediates and derivatives are described. The methods described herein allow the preparation of diastereomeric forms of compound having formula 1. The compounds of the invention are GARFT inhibitors.

专利号:US-6803447-B2
优先权日:2002-08-16
标题:Preparation of supramolecular polymers by copolymerization of monomers containing quadruple hydrogen bonding units with regular monomers
发明人：JANSSEN HENRICUS MARIE; VAN GEMERT GABY MARIA LEONARDA; TEN CATE AAFKE TESSA; VAN BEEK DIMPHNA JOHANNA MARIA; SIJBESMA RINTJE PIETER; MEIJER EGBERT WILLEM; BOSMAN ANTON WILLEM
权利人:EUTECHPARK MMP1 28
摘要:The invention relates to the synthesis of polymers containing self-complementary quadruple hydrogen groups by copolymerizing monomers containing a quadruple hydrogen bonding group with one or more monomers of choice. The resulting polymers show unique new characteristics due to the presence of additional physical interactions between the polymer chains that are based on multiple hydrogen bonding interactions (supramolecular interactions).