专利号:US-5135925-A 优先权日:1990-04-06 标题 :Use of zinc acexamate in the prophylaxis of gastropathy induced by non-steroidal anti-inflammatory drugs 发明人:VINAS ANTONIO B 权利人:VINAS LAB 摘要:Zinc acexamate acts by increasing the synthesis of mucus, reinforces the mucous barrier, improves the microcirculation and increases the synthesis of prostaglandins in the gastric mucous membrane, whereby it is effective in the treatment of said gastropathy, contrary to the results obtained with antiacids or antisecretory agents.
专利号:US-7842670-B2 优先权日:2005-04-01 标题:Cosmetic and pharmaceutical compounds for inducing the synthesis of SIRT proteins in skin and methods of use thereof 发明人:DAL FARRA CLAUDE; DOMLOGE NOUHA; BOTTO JEAN-MARIE 权利人:ISP INVESTMENTS INC 摘要:A cosmetic dermo-pharmaceutical, or dermatological composition having as an active agent in an acceptable cosmetic or pharmaceutical medium, at least one compound able to activate the synthesis or SIRT proteins in skin cells.
专利号:US-2023111600-A1 优先权日:2019-12-17 标题 :Polymeric fatty acid compounds for the treatment of fibrous amino acid-based substrates, especially hair 发明人:WAGNER ROLAND; STREICHER KATHARINA; ROHMANN LAURA; WENSKE CHRISTIAN; HAVELI SHRUTISAGAR DATTATRAYA 权利人:MOMENTIVE PERFORMANCE MAT GMBH 摘要:The present invention is directed at mono-, di- or polyquaternary ammonium compounds of the formula (I) wherein x is 1 to 50, and F can be the same or different and is represented by the general formula (II) wherein at least one of the optionally substituted and optionally functional-group-containing hydrocarbon radicals R 1 , R 2 , R 3 , R 4 or R 5 contains at least one estolide moiety comprising two or more ester or amide moieties. The invention also relates to a process for the synthesis of such compounds, the use of the compounds in cosmetic formulations for skin and hair care, cosmetic compositions for the treatment of fibers, and compositions containing one or more of the compounds for the treatment of hair.
专利号:US-2009082278-A1 优先权日:2005-04-01 标题 :Use of compounds inducing the synthesis of sirt proteins in or for the preparation of a cosmetic or pharmaceutical composition
专利号:US-10995078-B2 优先权日:2013-03-13 标 题:Compounds and compositions for inhibition of FASN 发明人:BAIR KENNETH W; LANCIA JR DAVID R; LI HONGBIN; LOCH JAMES; LU WEI; MARTIN MATTHEW W; MILLAN DAVID S; SCHILLER SHAWN E R; TEBBE MARK J 权利人:FORMA THERAPEUTICS INC 摘要:The present invention relates to compounds and composition for inhibition of FASN, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:
专利号:US-12336981-B2 优先权日:2010-09-03 标题 :Compounds and compositions for the inhibition of NAMPT 发明人:BAIR KENNETH W; BAUMEISTER TIMM R; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; DRAGOVICH Peter; GOSSELIN FRANCIS; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; ROTH BRUCE; SMITH CHASE C; WANG ZHONGGUO; YUEN PO-WAI; ZHENG XIAOZHANG 权利人:VALO HEALTH INC; GENENTECH INC 摘要:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below: