CAS: 6542-60-5; 2-Cyclopropylacetonitrile

相似化合物

5239-82-7 20778-47-6 5500-21-0

上下游产品

potassium cyanide cyclopropylcarbinyl bromide Cyclopropylmethanol sodium cyanidecyclopropylacetic acid 2-(cyclopropyl)ethylamine 1,2-dicyclopropylethanone 2-cyclopropyl-1-phenylethanone

Cyclopropylacetaldehyde Oxime置于乙酸酐体系中,用 乙酸乙酯 作为反应溶剂,化学反应 3.5H,以76.7%的收率获得产物环丙乙腈
参考文献:Ep1445248
标题:Ep1445248

专利信息

专利号:US-10226449-B2
优先权日:2013-12-20
标 题:Heterocyclic modulators of lipid synthesis and combinations thereof
发明人：HEUER TIMOTHY SEAN; OSLOB JOHAN D; MCDOWELL ROBERT S; JOHNSON RUSSELL; YANG HANBIAO; EVANCHIK MARC; ZAHARIA CRISTIANA A; CAI HAIYING; HU LILY W; DUKE GREGORY; OHOL-GUPTA YAMINI; O'FARRELL MARIE
权利人:3 V BIOSCIENCES INC
摘要:Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by dysregulation of a fatty acid synthase pathway by the administration of such compounds and combinations of such compounds and other therapeutic agents.

专利号:US-9428502-B2
优先权日:2012-07-03
标题:Heterocyclic modulators of lipid synthesis
发明人：OSLOB JOHAN D; MCDOWELL ROBERT S; JOHNSON RUSSELL; YANG HANBIAO; EVANCHIK MARC; ZAHARIA CRISTIANA A; CAI HAIYING; HU LILY W; WAGMAN ALLAN S
权利人:3-V BIOSCIENCES INC
摘要:Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by disregulation of a fatty acid synthase pathway by the administration of such compounds.

专利号:US-7569606-B2
优先权日:2006-01-26
标 题 :Platinum complexes with mononitrile-containing ligands
发明人：XIAO ZEJUN; HAUSHEER FREDERICK H; PETLURU PAVANKUMAR
权利人:BIONUMERIK PHARMACEUTICALS INC
摘要:Disclosed herein are novel platinum-based complexes possessing one nitrile substituent group (mononitrile) covalently-bonded to the platinum, one or more nitrogen donor ligands capable of forming hydrogen bonds with the bases in DNA or RNA and leaving groups (i.e., L 1 and L 2 )which can be hydrolyzed iii vivo to active species, which can then form coordinate adducts with DNA or RNA at the Guanine or Adenine bases thereof. Also disclosed herein are the reaction schemes for the synthesis of said platinum complexes, as well as methods of treatment of various types of cancer by the administration of a pharmaceutically-effective dose of said novel platinum complexes.

专利号:US-4492799-A
优先权日:1979-07-02
标题 :Halo-4-alkenoic acids and their use as pesticidal intermediates
发明人：WHEELER THOMAS N
权利人:UNION CARBIDE CORP
摘要:Novel halo-4-alkenoic acid compounds which are useful intermediates for the synthesis of insecticides and miticides.

专利号:US-7777060-B2
优先权日:2007-02-14
标题:Platinum analogs with bis-nitrile-containing ligands
发明人：CHEN XINGHAI; PETLURU PAVANKUMAR N V; HUANG QIULI; NARKUNAN KESAVARAM; HAUSHEER FREDERICK
权利人:BIONUMERIK PHARMACEUTICALS INC
摘要:Disclosed herein are novel platinum-based analogs possessing two nitrile substituent groups (bis-nitrile) covalently-bonded to the platinum. Also disclosed herein are the reaction schemes for the synthesis of said platinum complexes, as well as quantitative in vitro IC50 data.

专利号:WO-2008035086-A2
优先权日:2006-09-22
标题:Synthesis of leukotriene compounds