CAS: 107438-79-9; Ginkgolide J

专利信息

专利号:US-6693091-B2
优先权日:2002-03-29
标 题 :Analogs of terpene trilactones from Ginkgo biloba for bioorganic and imaging studies
发明人：STROMGAARD KRISTIAN; SUEHIRO MAKIKO; NAKANISHI KOJI
权利人:UNIV COLUMBIA
摘要:A compound having the structure: n wherein R 1 is H, OH, a photoactivatable moiety, a fluorescent moiety, or a radioactive moiety; n wherein R 2 is H, OH, a photoactivatable moiety, a fluorescent moiety, or a radioactive moiety; n wherein R 3 is H or OH; n wherein R 4 is H, OH, a photoactivatable moiety, a fluorescent moiety, or a radioactive moiety; and n wherein at least one of R 1 , R 2 , R 3 , or R 4 is a photoactivatable moiety, a fluorescent moiety, or a radioactive moiety. Optically pure enantiomers and salts of the compound are also described. Also, the synthesis of the compound, and uses of the compound, such as in a method for detecting the localization of, or identifying, receptors, enzymes or other targets, whether in a cell or in a subject.

专利号:US-2009221019-A1
优先权日:2005-06-22
标 题:Core-Modified Terpene Trilactones From Ginkgo Biloba Extract and Biological Evaluation Thereof
发明人：NAKANISHI KOJI; DZYUBA SERGEI; ISHII HIDEKI
权利人:NAKANISHI KOJI; DZYUBA SERGEI; ISHII HIDEKI
摘要:Lactone-rings of ginkgolides are converted into the corresponding tetrahydrofuran moieties via DIBAL-H reduction followed by deoxygenation of the formed lactols with Et 3 SiH/BF 3 Et 2 O producing a series of lactol-free ginkgolides. The present invention also relates to synthesis of hydroxyl-free, or hydroxyl-free and lactone-free, ginkgolides and bilobalides.

专利号:CN-108117561-A
优先权日:2016-11-30
标 题 :A kind of mesylate amine ginkgolide B metabolite and its synthesis and purification method