CAS: 628-17-1; 1-Iodopentane

该化合物是一种有机化合物,被归类为主要烷基卤化物,由五碳直链烷(丙烷)组成,与第一个碳相连的碘原子.该化合物一般在室温下无色可粉黄,具有特殊的气味.其分子式为C5H11I,与其他卤化化合物相比,它有一个相对较低的沸点,这表明其挥发性.1-Iodopentane在有机溶剂中溶解,但由于其盐酸碱链,在水中溶解性有限.该化合物通常用作有机合成剂或中间剂,用于制作其他化学化合物,包括药品和农用化学品.此外,它可以参与核循环生物学替代反应,使它成为合成有机化学中有价值的化合物.在处理1-odoptenane时,应当采取安全防范措施,因为如果吸入或吸入,它可能有害,那么处理1-odopentane时应当使用适当的保护设备.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

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合成工艺路线路线简述

    1-氯戊烷置于五羰基铁 碘仿体系中,化学反应 1.5H,反应生成 1-碘戊烷
    参考文献:Exchange Of Bromine And Chlorine By Iodine In Aliphatic Halides Catalyzed By Iron Pentacarbonyl
    标题:Exchange Of Bromine And Chlorine By Iodine In Aliphatic Halides Catalyzed By Iron Pentacarbonyl
    摘要:
    DOI:10.1007/bf01157365

    海关参考信息

    专利信息


    专利号:US-8084007-B2
    优先权日:2004-01-30
    标题 :Methods of synthesis of isotropically enriched borohydride and methods of synthesis of isotropically enriched boranes
    发明人:SPIELVOGEL BERNARD; COOK KEVIN S
    权利人:SPIELVOGEL BERNARD; COOK KEVIN S; SEMEQUIP INC
    摘要:The invention provides new methods for the synthesis of isotopically enriched metal borohydrides, metal tetrahydroundecaborate salts, and decaborane from isotopically enriched 10 B-boric acid or 11 B-boric acid. The invention is particularly useful for synthesis of isotopically enriched sodium or lithium borohydride, MB 11 H 14 (where M is Li, Na, K, or alkylammonium), and decaborane.

    专利号:WO-2021038581-A1
    优先权日:2019-08-30
    标题 :A one step synthesis of 2-substituted benzo[b]thiophenes
    发明人:SEKAR GOVINDASAMY; POONGUZHALI ELAMVAZHUTHI
    权利人:INDIAN INST TECH MADRAS
    摘要:The invention pertains to a one step synthesis of 2-substituted benzo[ b ]thiophene of general formula wherein the synthesis of 2-substituted benzo[ b ]thiophenes is by reacting the starting materials substituted or unsubstituted 2-halogenobenzaldehyde and substituted or unsubstituted acetyl/phenacyl bromide with a catalyst, a sulphur source and phase transfer catalyst in an aqueous medium with atmospheric air and at temperature in the range of 25°C-30°C.

    专利号:US-8907104-B2
    优先权日:2006-10-11
    标 题 :Synthesis of enone intermediate
    发明人:MYERS ANDREW G; BRUBAKER JASON D
    权利人:HARVARD COLLEGE
    摘要:The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The recent development of a modular synthesis of tetracycline analogs through a chiral enone intermediate has allowed for the efficient synthesis of novel tetracycline analogs never prepared before. The present invention provides a more efficient route for preparing the enone intermediate.

    专利号:US-7148356-B2
    优先权日:2001-07-13
    标题:Process for the catalytic synthesis of biaryls and polymers from aryl compounds
    发明人:SMITH III MILTON R; MALECZKA ROBERT E
    权利人:UNIV MICHIGAN STATE
    摘要:A process for producing organic substituted aromatic or heteroaromatic compounds including biaryl and biheteroaryl compounds in a two-step reaction. In the first step, the aromatic or heteroaromatic compound is borylated in a reaction comprising a borane or diborane reagent (any boron reagent where the boron reagent contains a B—H, B—B or B—Si bond) and an iridium or rhodium catalytic complex. In the second step, a metal catalyst catalyzes the formation of the organic substituted aromatic or heteroaromatic compound from the borylated compound and an electrophile such as an aryl or organic halide, triflate (OSO 2 CF 3 ), or nonaflate (OSO 2 C 4 F 9 ). The steps in the process can be performed in a single reaction vessel or in separate reaction vessels. The present invention also provides a process for synthesis of complex polyphenylenes starting from halogenated aromatic compounds.

    专利号:US-2015239796-A1
    优先权日:2014-02-19
    标题:One pot synthesis of 18f labeledtrifluoromethylated compounds with difluoro(iodo)methane
    发明人:RüHL THOMAS; RISS PATRICK; RAFIQUE WAQAS
    权利人:UNIV OSLO
    摘要:The present invention relates to compositions and methods for the synthesis of 18 F labeled compounds. In particular, the present invention relates to a copper (I) mediated one pot method for 18 F-trifluoromethylation of aromatic- or heteroaromatic halides with difluoro(iodo)methane (e.g., for use at PET imaging agents).

    专利号:US-2023174477-A1
    优先权日:2021-12-03
    标题:Methods for synthesis of the tricyclic prostaglandin d2 metabolite methyl ester
    发明人:DAI MINGJI; SIMS HUNTER
    权利人:PURDUE RESEARCH FOUNDATION
    摘要:Methods for the synthesis of a tricyclic-prostaglandin D 2 metabolite methyl ester or a pharmaceutically acceptable salt thereof.
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    主要参考文献

    参考标题:Simple Synthesis Of (Z)-12-Nonadecen-9-One, (Z)-13-Icosen-10-One, The Sex Pheromone Of Peach Fruit Moth, And (Z)-5-Undecen-2-One, A Biologically Active Molecule From The Pedal Gland Of The Bontebok
    作者:Masakazu Yamashita,Kaoru Matsumiya,Kotomi Murakami,Rikisaku Suemitsu |发布日期:1988.9
    摘要:A Simple And Convenient Synthesis Of (Z)-12-Nonadecen-9-One, (Z)-13-Icosen-10-One, The Sex Pheromone Of The Peach Fruit Moth, And (Z)-5-Undecen-2-One, The Pheromone From The Pedal Gland Of The Bontebok, Is Described. These Pheromones Were Readily Synthesized Using Successive Alkylation Of Acetone Dimethylhydrazone In One-Pot.

    合成参考文献


    摘要:Bauer, I.; Knölker, H.-J., Science of Synthesis, (2009) 46, 637.
    摘要:Kantchev, E. A. B.; Organ, M. G., Science of Synthesis, (2009) 48, 32.
    摘要:Landais, Y., Science of Synthesis Knowledge Updates, (2013) 3, 65.
    摘要:Joule, J. A., Science of Synthesis Knowledge Updates, (2010) 2, 377.
    摘要:Stanforth, S. P., Science of Synthesis Knowledge Updates, (2014) 3, 74.
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