CAS: 69411-68-3; 3-Fluoro-4-(Trifluoromethyl)Aniline

上下游产品

2-氟-4-硝基苯并三氟 2-Fluoro-4-Nitro-1-(Trifluoromethyl)Benzene 69411-67-2

2-氟-4-硝基苯甲酸置于盐酸,Sulfur Tetrafluoride,氢氟酸,铁粉,氯化铵体系中,用 水,异丙醇 作为反应溶剂,化学反应 24.0H,反应生成 4-氨基-2-氟三氟甲苯
参考文献:(杂)芳族酸的脱氧氟化.
标题:(杂)芳族酸的脱氧氟化.
摘要:通过用四氟化硫对肉桂酸和(杂)芳族羧酸进行脱氧氟化反应,合成了不同的三氟甲基取代的化合物.所得产物用作制备新型氟化氨基酸,苯胺和脂肪胺的原料,这些氟化物是药物化学和农业化学的重要组成部分.
DOI:10.1021/acs.Joc.9B03011

专利信息

专利号:US-4264775-A
优先权日:1976-10-27
标 题:Synthesis of β-aminostyrenes
发明人：WHITE WILLIAM A
权利人:LILLY CO ELI
摘要:A simple process for the preparation of beta -aminostyrenes proceeds from anilines by successively diazotizing, reacting with a vinyl ester, and reacting with a secondary amine without purification of the intermediate products. The compounds are reactive enamines useful in organic synthesis.

专利号:CN-107382742-A
优先权日:2017-07-30
标题:A new method for the synthesis of aromatic trifluoromethyl-containing intermediate 5-chloro-2-fluoro-4-(trifluoromethyl)aniline hydrochloride

专利号:US-4411912-A
优先权日:1978-02-16
标 题 :Insecticidal isovaleric acid esters
发明人：HENRICK CLIVE A; GARCIA BARBARA A
权利人:ZOECON CORP
摘要:Esters and thiolesters of amino acids, intermediates therefor, synthesis thereof, and the use of said esters and thiolesters and compositions for the control of pests.

专利号:US-2016229847-A1
优先权日:2013-10-04
标 题:Novel bicyclic pyridinones as gamma-secretase modulators
发明人：PETTERSSON MARTIN YOUNGJIN; AM ENDE CHRISTOPHER WILLIAM; GREEN MICHAEL ERIC; JOHNSON DOUGLAS SCOTT; KAUFFMAN GREGORY WAYNE; O'DONNELL CHRISTOPHER WILLIAM; PATEL NANDINI CHATURBHAI; STEPAN ANTONIA FRIEDERIKE; STIFF CORY MICHAEL; SUBRAMANYAM CHAKRAPANI; TRAN TUAN PHONG; VERHOEST PATRICK ROBERT
权利人:PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula II as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.