CAS: 32159-21-0; (S)-1-((Benzyloxy)Carbonyl)-5-Oxopyrrolidine-2-Carboxylic Acid

上下游产品

CAS号497-19-8 纯碱 | CAS号501-53-1 氯甲酸苄酯 | CAS号98-79-3 L-焦谷氨酸 | CAS号4124-76-9 benzyl N-(2,6-d... | CAS号1155-62-0 N-苄氧羰基-L-谷氨酸 | CAS号23356-96-9 L-脯氨醇 | CAS号5891-45-2 |N|-苄氧羰基-L-谷氨酸 1-叔丁酯 | CAS号124620-51-5 5-羟基-N-苄氧羰基-L-正... | CAS号75857-94-2 1-Benzyl 2-meth...

N-苄氧羰基-L-脯氨酸置于甲烷磺酸,Ketoabno,水,Lithium Perchlorate体系中,用 乙腈 作为反应溶剂,以86%的收率获得产物cbz-L-焦谷氨酸
参考文献:功能化吡咯烷的选择性电化学氧化
标题:功能化吡咯烷的选择性电化学氧化
摘要:描述了一种选择性电化学氨氧基介导的 Shono 型氧化吡咯烷为吡咯烷酮的方法.这些转化显示出高选择性和官能团兼容性.这种化学反应还展示了使用操作简单的 Electrasyn 2.0 和具有成本效益的不锈钢电极对功能化吡咯烷进行电化学氧化.
DOI:10.1021/acs.Orglett.1C03338

专利信息

专利号:US-3974135-A
优先权日:1971-06-24
标题:Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for producing the same
发明人：FOLKERS KARL; SIEVERTSSON HANS
权利人:FOLKERS KARL; SIEVERTSSON HANS
摘要:A synthetic decapeptide, L-pglutamyl-L-histidyl-L-tryptophanyl-L-seryl-L-tyrosyl-glycyl-L-leucy l-L-arginyl-L-prolyl-glycinamide having the hormonal activity of the luteinizing hormone releasing hormone (LRH) of the hypothalamus gland of mammals is provided by utilizing, as key starting materials, the amino acids, pyroglutamic acid, histidine, tryptophan, serine, tyrosine, glycine, leucine, arginine, proline. Synthesis of the decapeptide is accomplished by coupling, in appropriate protected forms, all of the remaining amino acids, individually or in combination, to the starting amino acid, or amino acid group or to the terminal amino acid resulting from combinations with one or more other amino acids, bound to a resin or carrier followed by release of the decapeptide from the carrier as the amide or other form which is converted to the amide, L-pglutamyl-L-histidyl-L-tryptophanyl-L-seryl-L-tyrosyl-glycyl-L-leucy l-L-arginyl-L-prolyl-glycinamide.

专利号:US-5342970-A
优先权日:1991-05-30
标 题 :Hydrosoluble coumarin derivatives, their preparation and their use as an enzyme substrate or for the preparation of such substrates
发明人：CHALOM JOSEPH; GRIFFOUL CHRISTINE; TOD MICHEL; REVEILLEAU STEPHANE
权利人:EUROBIO LAB
摘要:The invention relates to hydrosoluble coumarin derivatives. These derivatives comply with the formula: (I) in which R1 represents (OCH2CH2)mOCH2R7 or (OCH(CH3)CH2)mOCH2R7 with m=1 to 30 and in which R7 can be a hydrogen atom or various groups, R2 to R6 can be different substituents, particularly substituents making it possible to introduce into the derivative an appropriate group as the enzyme substrate or for the synthesis of enzyme substrates.

专利号:US-6339160-B1
优先权日:1997-07-17
标题:Metalloproteinase inhibitors, their therapeutic use and process for the production of the starting compound in the synthesis thereof
发明人：POLITI VINCENZO; GAVUZZO ENRICO; GALLINA CARLO; STAZIO GIOVANNI DI; D ALESSIO SILVANA; SELLA ANTONIO; PIAZZA CINZIA; GIORDANO CESARE; GORINI BARBARA; PANINI GABRIELLA; PARADISI MARIO PAGLIALUNGA; CIRILLI MAURIZIO; POCHETTI GIORGIO; MAZZA FERNANDO
权利人:POLIFARMA SPA; CONSIGLIO NAZIONALE RICERCHE
摘要:Objects of the present invention are compounds of a peptido-mimetic character having the capacity of acting as inhibitors of metalloproteinases produced by venom of snake, and of other metalloproteinases of human origin which have been put in relation with various pathologies in man, including tumoral growth and metastatization, aterosclerosis, multiple sclerosis, Alzheimer's disease, osteoporosis, hypertension, rheumatoid arthritis and other inflammatory diseases. n Object of the present invention is also the procedure for the production of diethylester of (1)-phosphotryptophan, as an initial product necessary to synthesize all compounds mentioned above.

专利号:US-3941763-A
优先权日:1975-03-28
标题:PGlu-D-Met-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 and intermediates
发明人：SARANTAKIS DIMITRIOS
权利人:AMERICAN HOME PROD
摘要:The synthesis of the decapeptide pGlu-D-Met-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 by solid-phase techniques is described. The decapeptide inhibits LH release.

专利号:EP-1019434-A2
优先权日:1997-07-17
标题 :Inhibitors of metalloproteinases, their therapeutic use, and process for the production of the starting compound in their synthesis

专利号:WO-9903878-A2
优先权日:1997-07-17
标 题 :Inhibitors of metalloproteinases, their therapeutic use, and process for the production of the starting compound in their synthesis