CAS: 3616-19-1; α-D-Cellobiose Octaacetate

上下游产品

CAS号133-99-3 D(+)-纤维二糖 | CAS号108-24-7 乙酸酐 | CAS号4753-07-5 Bromo Heptaacet... | CAS号63-42-3 乳糖 | CAS号3068-32-4 2,3,4,6-四乙酰氧基-a... | CAS号51450-24-9 六-O-乙酰基-呋喃葡烯糖-5-半乳糖甘 | CAS号84034-75-3 4-硝苯基-β-D-乳糖苷七乙酸酯 | CAS号572-09-8 2,3,4,6-四乙酰氧基-a... | CAS号63-42-3 乳糖 | CAS号67310-53-6 苄基β-D-乳糖苷七乙酸酯 | CAS号69266-16-6 1-叠氮-1-脱氧-Β-D-吡喃乳糖苷 | CAS号74513-17-0 正辛基-Β-D-乳糖苷 | CAS号65207-55-8 D-乳醛 | CAS号4419-94-7 4-硝基苯基-β-D-乳糖苷

纤维素二糖,乙酸酐置于吡啶,4-二甲氨基吡啶体系中,用100%的收率获得产物4-O-(2,3,4,6-四-O-乙酰基)-β-D-吡喃(型)葡糖基-D-吡喃(型)葡糖四乙酸酯
参考文献:带有寡糖作为亲水基团的1,3-二-O-烷基-2-O-(β-糖基)甘油的合成.
标题:带有寡糖作为亲水基团的1,3-二-O-烷基-2-O-(β-糖基)甘油的合成.
摘要:提出了一系列新的合成糖脂,1,3-二-O-烷基-2-O-(β-糖基)甘油及其有效合成途径.这些甘油糖脂通过三氯乙酰亚氨酸酯与1,3-二-O-烷基甘油的糖基化反应以五步合成,具有非常好的总收率和立体选择性.该方法用于制备带有纤维寡糖或麦芽寡糖的糖脂,其中糖残基的数目为一到六个.薄层色谱法,元素分析,核磁共振谱和红外吸收谱证实,这些糖脂是化学纯的化合物.
DOI:10.1016/0009-3084(94)90094-9

专利信息

专利号:US-5606041-A
优先权日:1992-06-26
标题:Process for steroidal peracyl glycosides
发明人：BUSCH FRANK R; GOGGIN KATHLEEN D; LAMBERT JOHN F; SHINE RUSSELL J; WALINSKY STANLEY W
权利人:PFIZER
摘要:Processes for the synthesis of tigogenin beta-O-cellobioside heptaalkanoate which is an intermediate for the known hypo-cholesterolemic agent tigogenin beta-cellobioside. The process comprises reacting α-cellobiosyl bromide heptaalkanoate and β-tigogenin in the presence of zinc fluoride or zinc cyanide under conditions capable of forming said tigogenyl β-O-cellobioside heptaalkanoate. The analogous preparations of hecogenin β-O-cellobioside heptaalkanoate 11-ketotigogenin β-O-cellobioside heptaalkanoate, and diosgenin β-O-cellobioside heptaalkanoate are also disclosed. The process provides both high β-anomeric selectivity and high yields.

专利号:US-5530107-A
优先权日:1992-10-15
标 题:Method for making steroidal peracyl glycosides
发明人：ALLAN DOUGLAS J M; BUSCH FRANK R; LAMBERT JOHN F; SHINE RUSSELL J; WALINSKY STANLEY W
权利人:PFIZER
摘要:Processes for the synthesis of tigogenin beta-O-cellobioside heptaalkanoate which is an intermediate for the known hypocholesterolemic agent tigogenin beta-cellobioside. The process comprises reacting α-cellobiosyl bromide heptaalkanoate and β-tigogenin in the presence of zinc fluoride or zinc cyanide under conditions capable of forming said tigogenyl β-O-cellobioside heptaalkanoate. The analogous preparations of hecogenin β-O-cellobioside heptaalkanoate, 11-ketotigogenin β-O-cellobioside heptaalkanoate, and diosgenin β-O-cellobioside heptaalkanoate are also disclosed. The process provides both high β-anomeric selectivity and high yields.

专利号:US-5563259-A
优先权日:1992-06-26
标 题:Process for making β-O-cellobiosyl steroid derivatives and trimethyl silyl steroid intermediates used therein
发明人：GOGGIN KATHLEEN D; LAMBERT JOHN F; WALINSKY STANLEY W
权利人:PFIZER
摘要:A process for the synthesis of peracyl-1-O-steroidal-β-cellobiosides that provides excellent β-anomeric selectivity without the use of a metal salt promoter. The process comprises reacting heptaacyl-β-D-cellobiosyl-1-fluoride and a trisubstituted silyl-3-O-steroid, wherein the steroid is tigogenin, hecogenin, 11-ketotigogenin or diosgenin in the absence of a metal salt under suitable conditions.

专利号:US-5010185-A
优先权日:1989-06-13
标 题:Processes for tigogenin beta-cellobioside
发明人：URBAN FRANK J
权利人:PFIZER
摘要:Improved processes for the synthesis of tigogenin beta-cellobioside, a known hypocholesterolemic agent, using cellobiose heptaacetate and tigogenin as starting materials.

专利号:US-8722864-B2
优先权日:2010-07-22
标 题 :Glycosylated acetaminophen pro-drug analogs
发明人：SHULL BRIAN; BALDWIN JOHN; GOPALASWAMY RAMESH; HAROON ZISHAN
权利人:SHULL BRIAN; BALDWIN JOHN; GOPALASWAMY RAMESH; HAROON ZISHAN; NUTEK PHARMA LTD
摘要:The present invention relates to methods and compositions for the synthesis, production, and use of pro-drug analogs of the analgesic acetaminophen. This invention relates to a method for the production of a broad group of glycosides of acetaminophen derivatives.

专利号:US-5294703-A
优先权日:1992-05-01
标 题:Process for preparing α-D-cellobiose octaacetate
发明人：HYATT JOHN A; SANDER TONY L; NAYLOR D MARK; BERNARD BOBBY L
权利人:EASTMAN KODAK CO
摘要:Provided is a novel improved process for the preparation of α-D-cellobiose octaacetate via the acetylative degradation of cellulose or cellulose acetate. The title compound is provided in high yield and quality in a facile one-pot process, amenable to large-scale synthesis.