CAS: 83055-99-6; Bensulfuron-Methyl

该化合物是一种选择性除草剂,主要用于控制各种作物,特别是大米的宽叶草和某些草,属于灭草剂的磺酰亚类,其作用是抑制对植物氨基酸合成至关重要的酶乙酰醚合成酶(ALS),其特点是其低施用率高,使其与传统除草剂相比是一种环境上有利的选择.本硫-甲基通常根据目标杂草和作物类型,在出血前或出血后施用.该物质在水中具有中度溶解,具有相对低的挥发性,有助于将非目标效应的风险降至最低.该物质在土壤中的残留活动也众所周知,如果不妥善管理,则会影响以后的作物.安全数据表明,尽管它对水生生物构成一些风险,但一般认为在使用标签指示时对人类和非目标物种具有低毒性.

结构式图片

欧盟法规

统一分类与标签REACH注册ECHA物质工作场所安全标识要求ECHA物质C&L通报REACH预注册废弃物危险特性清单

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CAS号99283-01-9 苄嘧黄隆

合成工艺路线路线简述

  • 917-61-3 + 103342-27-4 + 36315-01-2 = 83055-99-6
    反应条件:1.1 Catalysts: Pyridine Solvents: Acetonitrile; Rt1.2 Solvents: Acetonitrile; Rt; 3 H,40 °C
    标题:Synthesis Of 2-[[[[[(4,6-Dimethoxy-2-Pyrimidinyl)Amino]Carbonyl]Amino]Sulfonyl]Methyl]Benzoic Acid Methyl Ester (Herbicide Bensulfuron-Methyl) By Sodium Cyanate Method
    作者:Wang,Yan; Et Al
    参考文献:Huaxue Shijie 日期:2008 卷标:49(11) 页码:685-687
2-氨基磺酰甲基苯甲酸甲酯置于异氰酸正丁酯体系中,用 5,5-Dimethyl-1,3-Cyclohexadiene 作为反应溶剂,化学反应 3.33H,反应生成 苄嘧磺隆
参考文献:Jp2023/65730
标题:Jp2023/65730

海关参考信息

专利信息


专利号:US-7655445-B2
优先权日:2003-11-12
标题 :Methods for synthesis of sulfated saccharides
发明人:ROSENBERG ROBERT D; BALAGURUNATHAN KUBERAN
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:The present invention provides methods, processes and reaction mixtures, which produce sulfated heparosan polysaccharides. This invention also provides methods and reaction mixtures for the synthesis of N-deacetylate N-sulfate derivatives of non-sulfated N-acetyl heparosan (HS) polysaccharides.

专利号:US-2015031898-A1
优先权日:2012-03-09
标题 :Process for preparation of prostaglandin f2 alpha analogues
发明人:DAMS IWONA; KUTNER ANDRZEJ; CHODYNSKI MICHAL; KRUPA MALGORZATA; PIETRASZEK ANITA; ZEZULA MARTA; CMOCH PIOTR; KOSINSKA MONIKA
权利人:INST FARMACEUTYCZNY
摘要:A convergent synthesis of the prostaglandin F 2α analogues, travoprost and bimatoprost, was developed employing Julia-Lythgoe olefination of the structurally advanced phenylsulfone with an enantiomerically pure aldehyde ω-chain synthon. The novel convergent strategy allows the synthesis of a whole series of prostaglandin analogues of high purity from a common and structurally advanced prostaglandin intermediate.

专利号:US-2014349962-A1
优先权日:2013-05-24
标 题 :Rapid two-step synthesis of anti-coagulants
发明人:ROSENBERG ROBERT D; BALAGURUNATHAN KUBERAB
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:The present invention provides methods for the production of N-deacetylate N-sulfate derivatives of non-sulfated N-acetyl heparosan (HS) polysaccharides, compounds thus obtained and compositions comprising same. This invention also provides applications of N-deacetylate N-sulfate derivatives of non-sulfated N-acetyl heparosan (HS) polysaccharides, and compositions comprising same, for use in controlling coagulation and treating thrombosis.

专利号:US-8846373-B2
优先权日:2011-07-29
标 题 :Methods of using a bacterial GlcNAc-6-P 2′- epimerase to promote sialylation of glycoconjugates
发明人:GEISLER CHRISTOPH; JARVIS DONALD
权利人:GEISLER CHRISTOPH; JARVIS DONALD; UNIV WYOMING
摘要:The present invention relates to new methods to promote sialylation of glycoconjugates, including recombinant glycoproteins, in glycoconjugate production systems. The invention relates to methods to promote efficient glycoconjugate sialylation in recombinant expression systems, by providing simpler and more economical ways to produce large intracellular pools of sialic acid precursors. The invention is directed to nucleic acids, vectors, and cells harboring vectors comprising nucleic acids encoding enzymes involved in the synthesis of sialic acid precursors, and cells harboring these nucleic acids in combination with nucleic acids encoding glycosyltransferases, including sialyltransferases, to facilitate the production of humanized recombinant glycoproteins in bacterial, fungal, plant, and animal cell expression systems. The engineered cells can be used to produce glycosylated proteins in virally-infected, transiently-transformed, or stably-transformed host cells, including lepidopteran insects and cultured cell lines derived from Spodoptera frugiperda, Trichoplusia ni , and Bombyx mori that can be infected by baculovirus expression vectors.

专利号:WO-9630508-A1
优先权日:1995-03-24
标 题:Assembly of complex molecular and supramolecular objects and devices and uses thereof
发明人:RABANI ELY MICHAEL
权利人:RABANI ELY MICHAEL
摘要:The present invention provides method and means for synthesis of components comprising affinity groups, structural members and optionally functional members into assemblages having well controlled structure on the molecular and atomic scale. Methods are provided for the hierarchial construction of components and assemblages thereof which expand assemblage structure in a well controlled manner while retaining controlled addressability of affinity groups through differentiation of the specificity of affinity groups. Methods for the immobilization of such components or assemblages thereof to solid phases, particles, surfaces, actuators and sensors in well controlled manners are provided. Additional methods and means for effecting the controlled colocalization of objects comprising the components of the present invention are provided. The present invention has broad applicability to several technologically and industrially critical applications, as demonstrated by specific embodiments of the present invention useful in diverse applications.

专利号:US-8374348-B2
优先权日:2002-01-18
标题:Device for secure transmission recording and visualisation of audiovisual programmes
发明人:LECOMTE DANIEL
权利人:NAGRA FRANCE; LECOMTE DANIEL
摘要:A method of distributing video sequences according to a nominal flow format including a succession of frames each including at least one I block corresponding to a complete digital I image and at least one N block corresponding to differences between a digital N image and at least one other image including analyzing the flow of sequences to generate a first modified flow having a format of a nominal flow and having modified N blocks and a second flow of any format including digital information required to reconstruct the modified blocks; and transmitting the first and second flows from a server to destination equipment, and calculating on the destination equipment a synthesis of a flow in a nominal format as a function of the first flow and the second flow.
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主要参考文献


1: Wei S, Li P, Ji M, Dong Q, Wang H. Target-site resistance to bensulfuron-methyl in Sagittaria trifolia L. populations. Pestic Biochem Physiol. 2015 Oct;124:81-5. doi: 10.1016/j.pestbp.2015.05.001. Epub 2015 May 11. doi: 10.1007/s10532-012-9556-7. Epub 2012 May 22. doi: 10.1016/S1001-0742(13)60446-5. doi: 10.1016/j.jchromb.2015.05.008. Epub 2015 May 14. doi: 10.1007/s10646-012-0882-7. Epub 2012 Mar 20. Chinese. doi: 10.1007/s00244-010-9626-y. Epub 2010 Dec 3. doi: 10.1016/j.jhazmat.2008.02.115. Epub 2008 Mar 8. doi: 10.1021/jf803386v. Epub 2009 Apr 22. doi: 10.3389/fpls.2016.01970. eCollection 2016.
15: Lin X, Zhao Y, Fu Q, Umashankara ML, Feng Z. Analysis of culturable and unculturable microbial community in bensulfuron-methyl contaminated paddy soils. J Environ Sci (China). 2008;20(12):1494-500. doi: 10.1016/j.chemosphere.2011.02.055. Epub 2011 Apr 5. Chinese.

合成参考文献


参考文献:10.2116/analsci.22.835
摘要:Sasaki H, Yonekubo J, Hayakawa K. A new on-line sample preparation system for the liquid chromatography/time-of-flight mass spectrometry simultaneous analysis of pesticides in river water. Anal Sci. 2006 Jun;22(6):835–40. doi: 10.2116/analsci.22.835.
参考文献:10.1002/etc.582
摘要:Nagai T, Ishihara S, Yokoyama A, Iwafune T. Effects of four rice paddy herbicides on algal cell viability and the relationship with population recovery. Environ Toxicol Chem. 2011 Aug;30(8):1898–905. doi: 10.1002/etc.582.
参考文献:10.1016/j.pestbp.2015.05.001
摘要:Wei S, Li P, Ji M, Dong Q, Wang H. Target-site resistance to bensulfuron-methyl in Sagittaria trifolia L. populations. Pestic Biochem Physiol. 2015 Oct;124():81–5. doi: 10.1016/j.pestbp.2015.05.001.
参考文献:10.1007/s00604-019-3610-7
摘要:Chen L, Wu J, Huang X. Multiple monolithic fibers modified with a molecularly imprinted polymer for solid phase microextraction of sulfonylurea herbicides based on boron-nitrogen interaction. Mikrochim Acta. 2019 Jun 25;186(7):470. doi: 10.1007/s00604-019-3610-7.
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