CAS: 870-24-6; 2-Chloroethanamine Hydrochloride

相似化合物

71999-74-1 6288-63-7 6331-00-6

上下游产品

CAS号2002-24-6 盐酸乙醇胺 | CAS号7719-09-7 氧氯化硫 | CAS号68-12-2 N,N-二甲基甲酰胺 | CAS号141-43-5 2-氨基乙醇 | CAS号3891-07-4 N-羟乙基酞酰亚胺 | CAS号151-56-4 氮丙啶 | CAS号497-25-6 2-恶唑烷酮 | CAS号7647-01-0 盐酸 | CAS号108-88-3 甲苯 | CAS号42416-20-6 [2-(Pyridin-2-y... | CAS号36761-83-8 dechloroethylcy... | CAS号497-25-6 2-恶唑烷酮 | CAS号36155-35-8 2-[(4-CHLOROPHE... | CAS号14944-00-4 3, 4-二氢苯并[f][1,... | CAS号1779-81-3 2-氨基-2-噻唑啉 | CAS号4848-43-5 2-(二苯基膦基)乙胺 | CAS号40055-37-6 3-(4,5-二氢-2-噁唑基)-吡啶 | CAS号42137-88-2 N,N-二(2-氯乙基)对甲基苯磺酰胺 | CAS号92814-42-1 (R)-6-氨基-1,4-TH...

C.I.酸性橙108置于氯化亚砜体系中,用 氯仿 作为反应溶剂,化学反应生成 2-氯乙胺盐酸盐
参考文献:侧链对叔胺官能化多肽的ph和热响应性的影响
标题:侧链对叔胺官能化多肽的ph和热响应性的影响
摘要:侧链上的ph的结构影响的系统调查和叔胺官能化聚(热响应性升-谷氨酸)s(ta-的pgs)中的溶液中进行.通过铜(i)催化的叠氮基叔胺与聚(γ-炔丙基-L-谷氨酸)(pplg)的叠氮化物-炔烃环加成点击反应有效合成了ta-Pgs聚合物.进行了比浊法测量,以表征ta-Pg在水溶液中的ph和温度诱导的相变,这表明该性质对氮的结构依赖性取代基团和1,2,3-三唑环与侧链中叔胺基团之间的"连接基".详细地讲,Ta-Pg的ph响应特性基本上由侧链中n-取代基团的疏水性决定,Ph转变点(ph T)随着n-取代基团疏水性的增加而降低,而ta Pg的温度响应性受n取代基或"连接基"的影响.具有中等n取代胺基(例如dea,Pr和pd)或支链"连接子"(例如iso-丙烯和2-甲基丙烯基)更可能表达因ph值变化而调整的lcst型相变.这项研究揭示的这些结构-属性关系将有助于开发ta-Pg在智能药物输送系统中的应用.©2013
DOI:10.1002/pola.27048

专利信息

专利号:US-11370736-B2
优先权日:2019-04-01
标 题:Synthesis of fluoro hemiacetals via transition metal-catalyzed fluoro ester and carboxamide hydrogenation
发明人：DUB PAVEL A; BATRICE RAMI J; GORDON JOHN C
权利人:TRIAD NAT SECURITY LLC
摘要:This application is directed to use of transition metal-ligand complexes to hydrogenate fluorinated esters and carboxamides into fluorinated hemiacetals. Methods for synthesis of certain ligands are also provided.

专利号:US-7576234-B2
优先权日:2002-05-15
标题 :Synthesis of 2-alkyl amino acids
发明人：CHORGHADE MUKUND S; GURJAR MUKUND K; MOHAPATRA DEBENDRA K
权利人:GENZYME CORP
摘要:Non-natural amino acids such as 2-alkylated amino acids allow for the synthesis of a wider variety of peptidal and non-peptidal pharmaceutically active agents. A method of preparing a 2-alkyl amino acid involves a Michael-type addition of a nucleophile to a dialkyl 2-methylidenylpropan-1,3-dioate and the conversion of a ester moiety into an amino moiety. The present invention also discloses a method of preparing a class of iron chelating agents related to desferrithiocin, all of which contain a thiazoline ring. In this method, an aryl nitrile or imidate is condensed with cysteine, a 2-alkyl cysteine, or a cysteine ester.

专利号:US-2025011348-A1
优先权日:2023-06-13
标题:Synthesis Process of X-IPM, Stable Crystal Form and Application Thereof
发明人：DUAN JIANXIN; LU ZHAOQIANG; CAI XIAOHONG; FAN JINWEI; QIN WEI; HUANG QUNHUI; ZHANG YANJUN; CHEN WEISU
权利人:ASCENTAWITS PHARMACEUTICALS LTD
摘要:The present application relates to a new method for synthesizing isophosphoramide nitrogen mustard (X-IPM) that is suitable for industrialized production, involves fewer types of solvents, and leads to stable products with high yield. This method is charazterized mainly by the batchwise addition of M (e.g., M is R3N with R being ethyl; i.e., M is triethylamine) and the specific post-reaction treatment, which make it possible for the reaction to fully proceed, lead to products with less impurities, high yield and relatively stable properties, and can lead to stable crystallized substances with specific crystal structures. The present application also relates to stable crystal forms of the isophosphoramide nitrogen mustard (X-IPM) prepared by the aforementioned method, and use of the same as reactants for the synthesis of aziridine structure-containing compounds.

专利号:US-10131747-B2
优先权日:2013-10-02
标题:Poly(ethylene imine)-based copolymers for bonding to and releasing genetic material, in particular DNA/RNA, and method for the production and use of same
发明人：ENGLERT CHRISTOPH; TAUHARDT LUTZ; GOTTSCHALK MICHAEL; SCHUBERT ULRICH S
权利人:SMARTDYELIVERY GMBH
摘要:New poly(ethylene imine)-based copolymers for bonding to and releasing genetic material, in particular DNA/RNA, and method for the production and use of same. n The copolymers according to a compound of the general Formula I: n ncan be produced at low costs and with little expenditure of time, are tailor-made and have a high functionality for universal effective uses without restriction of their bonding affinity to genetic material.n nThe new copolymers are produced through a synthesis of the general Formula III:

专利号:US-6603003-B2
优先权日:2000-11-07
标 题 :Method for the preparation of piperazine and its derivatives
发明人：SEBASTIAN SONNY; PATEL HETAL VIRENDRA; THENNATI RAJAMANNAR
权利人:SUN PHARMACEUTICAL IND LTD
摘要:A novel method for the synthesis of piperazine and its derivatives of formula 1,wherein R is selected from hydrogen, or a lower alkyl group having 1 to 6 carbon atoms or a phenylalkyl group the alkyl of which has 1 to 4 carbon atoms;R1 is selected from hydrogen, a methyl group, a phenyl group optionally substituted with an alkyl group having 1 to 6 carbon atoms, or a phenylalkyl group the alkyl of which has 1 to 4 carbon atoms; andR2 is selected from hydrogen, or a methyl group, or a fluoromethyl group;comprising the steps:a. reacting an ester of formula 11 with substituted or unsubstituted ethylenediamine of formula 7 to give 3,4-dehydropiperazine-2-one and its derivatives of formula 12, wherein R, R1, R2 are as defined above and R6 is a C1 to C4 linear or branched alkyl group; andb. reacting the 3,4-dehydro-piperazine-2-one and its derivatives of formula 12 with a reducing agent to yield the piperazine and its derivatives of formula 1.

专利号:WO-0078725-A1
优先权日:1999-06-18
标题 :Synthesis of substituted amidines
发明人：CHOUEIRY DANIELE; GIRAUD DANIEL LIONEL; SCHOTTEN THEO
权利人:LILLY CO ELI; CHOUEIRY DANIELE; GIRAUD DANIEL LIONEL; SCHOTTEN THEO
摘要:The present invention provides a process for preparing amidines starting from carboxylic acid derivatives, in which the carboxylic acid containing moiety is attached to a sp3-, or sp?2- or sp1¿-hybridized carbon atom. The sp2-hybridized carbon atom, to which the carboxylic acid containing moiety is attached to may be part of an aromatic or heteroaromatic or olefinic system.