专利号:US-2025179012-A1 优先权日:2022-03-04 标 题:Synthesis of sulfur(vi) compounds and reagents for same 发明人:LOPCHUK JUSTIN MATTHEW; SHULTZ ZACHARY 权利人:H LEE MOFFITT CANCER CT & RES 摘要:This disclosure provides reagents and processes for the synthesis of organic compounds, more particularly reagents and processes for the asymmetric synthesis of sulfur (VI) containing organic compounds.
专利号:US-9901901-B2 优先权日:2012-05-21 标 题 :Selective extraction of anions from solution 发明人:MEZEI GELLERT 权利人:WESTERN MICHIGAN UNIV RESEARCH FOUNDATION; THE BOARD OF TRUSTEES OF WESTERN MICHIGAN UNIV 摘要:A method of selectively extracting anions from an aqueous solution using an anion encapsulating aggregate formed upon the addition of a solvent, a copper contributor, a hydroxide contributor, a counterion contributor, and pyrazole to an aqueous solution containing the anions, or upon the addition of a solvent, a polymeric chain of [Cu II (μ-OH)(μ-pz)] ∞ and a counterion contributor to the aqueous solution. The aggregates include compounds of the formula cis Cu II x (OR 1 ) y (R 2 pz) z , where R 1 is H or an alkyl group, R 2 is H, or an alkyl group or a charged group, pz is pyrazolate and each of x, y, and z is an integer between about 1 and about 40. In addition, ligand-containing anion encapsulating aggregates can be formed by synthesis with a lig-and-bound pyrazole or by substituting the ligand-bound pyrazole for the pyrazole incorporated in the aggregate.
专利号:US-10087197-B2 优先权日:2012-05-21 标 题:Selective extraction of anions from solution 发明人:MEZEI GELLERT 权利人:WESTERN MICHIGAN UNIV RESEARCH FOUNDATION 摘要:A method of selectively extracting anions from an aqueous solution using an anion encapsulating aggregate formed upon the addition of a solvent, a copper contributor, a hydroxide contributor, an optional counterion contributor, and at least one encapsulating anion to an aqueous solution containing the anions, or upon the addition of a solvent, a polymeric chain of [CuII(μ-OH)(μ-ea)]∞ and optionally, a counterion contributor to the aqueous solution. The aggregates include compounds of the formula cis-CuIIx(OR1)y(R2ea)z, where R1 is H or an alkyl group, R2 is H, or an alkyl group or a charged group, ea is an encapsulating anion, and each of x, y, and z is equal to an integer between about 1 and 40, inclusive. In addition, anion encapsulating aggregates can be formed by synthesis with alternate encapsulating anions by substituting alternate encapsulating anions for the encapsulating anion incorporated in the aggregate.
专利号:WO-2023168108-A2 优先权日:2022-03-04 标 题 :Synthesis of sulfur(vi) compounds and reagents for same
专利号:EP-4086245-A1 优先权日:2018-01-30 标 题 :Processes for preparing intermediates for the synthesis of a jak inhibitor
专利号:EP-1935869-A1 优先权日:2000-10-02 标题:Retinoids for the treatment of emphysema 发明人:LAPIERRE JEAN MARC; ROTSTEIN MARC; SJOGREN ERIC BRIAN 权利人:HOFFMANN LA ROCHE 摘要:The current invention provides novel retinoid compounds and methods for their synthesis, the use of such compounds for the preparation of medicaments for treating or preventing emphysema, cancer and dermatological disorders, methods for such deseases and pharmaceutical compositions suitable for the treatment or prevention of emphysema, cancer and dermatological disorders.
[参考文献]: A I Cederbaum, Et Al. Effects Of Pyrazole, 4-Bromopyrazole And 4-Methylpyrazole On Mitochondrial Function. Biochem Pharmacol. 1974 Jan 15;23(2):203-13. [参考文献]: E Alejandre-Durán, Et Al. Mutagenicity Study On Pyrazole, Seven Pyrazole Derivatives, And Two Nitroimidazoles With The L-Arabinose Resistance Test Of Salmonella Typhimurium. Environ Mutagen. 1986;8(4):611-9. [参考文献]: Ilia A. Guzei, Et Al. Structural Diversity In The Reaction Of Mono- And Disubstituted Pyrazoles With Titanium Tetrachloride. Importance Of Hydrogen Bonding And Trends In Cis/trans Geometry Of Binary Adducts With Unidentate Ligands. Inorg Chem. 1997 Sep 24;36(20):4415-4420. [参考文献]: Kamal Nayan Sharma, Et Al. Palladium(Ii) Complexes Of Pyrazolated Thio/selenoethers: Syntheses, Structures, Single Source Precursors Of Pd4Se And Pdse Nano-Particles And Potential For Catalyzing Suzuki-Miyaura Coupling. Dalton Trans. 2013 Mar 21;42(11):3908-18. [参考文献]: Todd D Senecal, Et Al. A General, Practical Palladium-Catalyzed Cyanation Of (Hetero)Aryl Chlorides And Bromides. Angew Chem Int Ed Engl. 2013 Sep 16;52(38):10035-9.
合成参考文献
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