CAS: 585-86-4; Lactitol

上下游产品

lactobionolactone 3-O-β-galactopyranosyl-D-galactose Cellobiose water4)-(1-deoxy-D-glucityl)-(1->N)-S2-(trityl)cysteamineβ-D-galactopyranosyl-(1-4)-(1-deoxy-D-glucityl)-(1-N)-S2-(trityl)cysteamine 4)-β-D-glucopyranoside2-azidoethyl β-D-galactopyranosyl-(1-4)-β-D-glucopyranoside lactitol nonaacetate Acetic acid (2R,3S,4R,5R,6R)-4,5-diacetoxy-6-acetoxymethyl-2-[(1R,2R,3S)-2,3,4-triacetoxy-1-((R)-1,2-diacetoxy-ethyl)-butoxy]-tetrahydro-pyran-3-yl ester

Lactose置于1-甲基吡咯烷,Ru-Macho-Bh,氢气体系中,用 乙醇 作为反应溶剂,150.0 °C,5.0 Mpa 条件下,反应 6.0H,反应生成 乳糖醇
参考文献:Ru-Macho-Bh 催化的糖的高效选择性加氢:糖醇的实用合成
标题:Ru-Macho-Bh 催化的糖的高效选择性加氢:糖醇的实用合成
摘要:通过使用均相催化剂的选择性氢化实现了糖醇的高效合成.pn H P-钌催化剂ru-Macho-Bh以极高的反应性和选择性促进氢化.该反应可应用于各种单糖和双糖,并已成功在几十克的规模上运行.
DOI:10.1021/acs.Oprd.2C00047

专利信息

专利号:EP-0349059-B1
优先权日:1988-06-29
标题:Process for the synthesis of polyol fatty acid polyesters
发明人：WILLEMSE GERARDUS W
权利人:UNILEVER NV; UNILEVER PLC
摘要:The application pertains to a process for the synthesis of polyol fatty acid polyesters, in which a polyol and/or a fatty acid oligoester thereof, is esterified by reaction with fatty acid lower alkylester under substantially solvent-free conditions at elevated temperature in the presence of a transesterification catalyst and, optionally an emulsifier, and in which at least during the final stage of the transesterification reaction the reaction mixture is submitted to the action of a stripping agent suitable for accelerating the removal of the lower alkyl alcohol formed in said reaction. The process is of particular advantage in the synthesis of polyesters of very high degrees of conversion.

专利号:US-5939304-A
优先权日:1997-06-05
标题:Method for synthesis of anhydrothrombin
发明人：SUZUKI TOYOAKI; HOSOKAWA KAZUYA; NAGATA MASANORI
权利人:FUJIMORI KOGYO CO
摘要:A method for a synthesis of anhydrothrombin is provided which features a short process, an easy procedure, and high yields. n The method comprises n (A) a step of causing an active serine residue site of thrombin to react with an inhibitor, n (B) a step of performing an alkali treatment at a pH of not less than 11, and n (C) a step of performing an operation of recovery, and carries out these steps sequentially in the order mentioned, and is characterized by causing at least the step of performing the operation of recovery to proceed in the presence of at least one compound selected from the group consisting of polyhydric alcohols and saccharides, and a salt or an amphoteric electrolyte.

专利号:US-12221452-B2
优先权日:2017-10-04
标题:Synthesis of cantharidin
发明人：DAVIDSON MATTHEW GENE; EKLOV BRIAN MATTHEW; WUTS PETER; LOERTSCHER BRAD MELVIN; SCHOW STEVEN R
权利人:VERRICA PHARMACEUTICALS INC
摘要:The invention provides synthetic methods for the preparation of cantharidin and analogs thereof. In one aspect, the invention provides an improved Diels-Alder cycloaddition to generate a key intermediate en route to cantharidin and analogs thereof. In certain embodiments, the new Diels-Alder reaction involves reacting Compound (2) in the presence of furan, and in the absence of acid or increased pressure, in an aprotic polar solvent with slight warming, to yield Compound (1) in favorable yield and exo-endo ratio. In another aspect, the invention also provides a new Diels-Alder reaction between compounds of Formula (III) and furan to yield compounds of Formula (IV), which can then be transformed into cantharidin or analogs thereof. In yet another aspect, the invention describes a new palladium-mediated carbonylation providing another key intermediate en route to cantharidin and analogs thereof. In addition to synthetic methods, present invention also provides compounds (i.e., intermediates) useful in the synthesis of cantharidin and analogs thereof. Compounds provided herein may have biological activity, and therefore may be used in the treatment of diseases or conditions (e.g., infectious diseases and skin conditions).

专利号:US-8105809-B2
优先权日:2008-07-03
标题 :Enzymatic synthesis of acetoacetate esters and derivatives
发明人：HENDERSON SAMUEL T
权利人:HENDERSON SAMUEL T; ACCERA INC
摘要:In one embodiment, the present invention includes a method for the synthesis of an ester derivative of acetoacetate. The method includes providing a first ester of acetoacetate and providing an alcohol. The method further includes combining the first ester of acetoacetate and the alcohol in the presence of an enzyme capable of transesterification in a non-aqueous solvent to form the ester derivative of acetoacetate. The method results in the formation of the ester derivative of acetoacetate, which, in one embodiment, is monoacetoacetin.

专利号:US-5144023-A
优先权日:1987-12-11
标 题:Process for the synthesis of polyol fatty acid esters
发明人：WILLEMSE GERARDUS W M
权利人:BERGH FOODS CO
摘要:The invention pertains to a process for the synthesis of polyol fatty acid sters involving transesterification under substantially solvent-free conditions in which the preparation of the starting reaction mixture for the esterification reaction comprises the step of spray-drying. The process provids a very convenient method of desolvatizing and homogenizing the reactants which is economically feasible on a technical scale.

专利号:WO-2020100075-A1
优先权日:2018-11-14
标题:Biocatalyst for the synthesis of lactitol-derived oligosaccharides with prebiotic properties for the production of functional foods
发明人：BARRIOS NARVÃ?EZ YURI; CHITO TRUJILLO DIANA MARÃ?A; MONTILLA CORREDERA ANTONIA; RADA MENDOZA MAITE DEL PILAR; RAMÃ?REZ SANABRIA ALFONSO ENRIQUE; VILLAMIEL GUERRA MARÃ?A DEL MAR
权利人:UNIV DEL CAUCA; CONSEJO SUPERIOR DE INVESTIG CIENTIIFICAS CSIC
摘要:The present invention relates to a biocatalyst for the synthesis of lactitol-derived oligosaccharides (LaOS), with potential prebiotic properties, which can be used to improve the industrial production of functional foods. The biocatalyst comprises one or more β-galactosidase enzymes immobilised, by means of a covalent bond, on a mesoporous silica support. The invention also relates to a method for synthesising oligosaccharides for the production of functional foods.