CAS: 149806-06-4; 6-Bromonicotinaldehyde

上下游产品

CAS号624-28-2 2,5-二溴吡啶 | CAS号68-12-2 N,N-二甲基甲酰胺 | CAS号73290-22-9 2-溴-5-碘吡啶 | CAS号693-04-9 正丁基氯化镁 | CAS号1068-55-9 异丙基氯化镁 | CAS号6311-35-9 6-溴烟酸 | CAS号154321-32-1 2-bromo-5-(dibr... | CAS号1603-41-4 2-氨基-5-甲基吡啶 | CAS号3510-66-5 2-溴-5-甲基吡啶 | CAS号154321-17-2 2-bromo-5-(dimo... | CAS号53014-84-9 5-甲酰基-2-甲基吡啶 | CAS号179873-48-4 [2,2'-联吡啶]-5-甲醛 | CAS号220904-17-6 2-溴-5-(1,3-二氧杂烷... | CAS号63056-20-2 6-苯基吡啶-3-甲醛 | CAS号100-55-0 3-吡啶甲醇 | CAS号131747-68-7 5-甲酰基吡啶-2-甲腈 | CAS号122306-01-8 6-溴吡啶-3-甲醇 | CAS号328547-41-7 4-[(5-FORMYL-2-... | CAS号356058-14-5 6-[4-(三氟甲基)苯基]-... | CAS号101990-45-8 2-溴-5-(溴甲基)吡啶

2,5-二溴吡啶置于盐酸,正丁基锂体系中,用 N,N-二甲基甲酰胺 用作溶剂,以64.8%的收率获得2-溴-5-醛基吡啶
参考文献:Oxime Derivatives For The Treatment Of Dyslipidemia And Hypercholesteremia
标题:Oxime Derivatives For The Treatment Of Dyslipidemia And Hypercholesteremia
摘要:本发明涉及formula (I)的化合物,可能在治疗疾病,如代谢紊乱,血脂异常和/或高胆固醇血症方面有用:

专利信息

专利号:US-6416861-B1
优先权日:1999-02-16
标题 :Organosilicon compounds and uses thereof
发明人：LEE YOUNGHEE; SILVERMAN RICHARD B
权利人:UNIV NORTHWESTERN
摘要:A compound of the formula: n and a resin-bound compound of the formula: n and their use in combinatorial chemistry and in the synthesis of compounds comprising at least one aromatic moiety is described, where R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , L 1 , P, Ar 1 , and X are as herein defined.

专利号:US-11780834-B2
优先权日:2018-06-21
标题:Solid forms of 3-((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3- yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol and processes for preparing fused tricyclic compounds comprising a substituted phenyl or pyridinyl moiety, including methods of their use
发明人：CHUNG CHEOL KEUN; XU JIE; IDING HANS; CLAGG KYLE; DALZIEL MICHAEL; FETTES ALEC; GOSSELIN FRANCIS; LIM NGIAP-KIE; MCCLORY ANDREW; ZHANG HAIMING; CHAKRAVARTY PAROMA; NAGAPUDI KARTHIK; ROBINSON SARAH
权利人:HOFFMANN LA ROCHE; GENENTECH INC
摘要:Provided herein are solid forms, salts, and formulations of 3-((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol, processes and synthesis thereof, and methods of their use in the treatment of cancer.

专利号:US-2011021532-A1
优先权日:2008-04-22
标题 :Novel substituted heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
发明人：POWELL DAVID; LEBRUN MARIE-EVE; BHAT SATHESH; RAMTOHUL YEEMAN K
权利人:MERCK FROSST CANADA LTD
摘要:Substituted heteroaromatic compounds of structural formula I are inhibitors of stearoyl-coenzyme A delta-9 desaturase. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; obesity; Type 2 diabetes; insulin resistance; hyperglycemia; Metabolic Syndrome; neurological disease; cancer; and liver steatosis. Formula (I).

专利号:US-2007275968-A1
优先权日:2004-09-07
标 题 :Substituted Biphenyl Derivative
发明人：KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
权利人:KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
摘要:The present invention relates to a biaryl derivative or a pharmacologically acceptable salt thereof having an excellent collagen-synthesis inhibition activity. A biaryl derivative having a structure represented by the following General Formula (I) or a pharmacologically acceptable salt thereof: n nwherein n R 1 represents a C 6 -C 10 aryl group which is substituted with one to three group(s) each independently selected from the group consisting of a group defined by formula R-L-, a di-(C 1 -C 6 alkyl)amino group, a di-(C 1 -C 6 alkyl)aminosulfonyl group, a hydroxyaminocarbonyl group, and a halogen atom, and so on; R represents a C 1 -C 6 alkyl group, and so on; L represents a sulfonyl group, an aminosulfonyl group, or a sulfonylamino group, and so on; R 2 represents a hydrogen atom, and so on; A represents a group defined by formula (II), (III), or (IV); R 3 represents a C 1 -C 6 alkyl group, and so on; and R 4 represents a C 1 -C 6 alkyl group, and so on.

专利号:CN-117510471-A
优先权日:2022-07-29
标题 :A kind of synthesis method of abeciclib