CAS: 2938-48-9; 3,3-Dimethyldihydro-2H-Pyran-2,6(3H)-Dione

相似化合物

4160-82-1 4166-53-4 185815-59-2

上下游产品

CAS号681-57-2 2,2-二甲基戊二酸 | CAS号110054-49-4 α,α-Dimethyl-gl... | CAS号562-46-9 4,4-二甲基-1,3-环己二酮 | CAS号3123-97-5 5,5-二甲基二氢呋喃-2(3H)-酮 | CAS号504-85-8 4-甲基-3-戊烯酸 | CAS号2938-49-0 Benzenepentanoi... | CAS号2979-69-3 4,4-二甲基-3,4-二氢萘... | CAS号3121-82-2 2,2-dimethylpen... | CAS号13051-32-6 2,2-二甲基戊二酸二甲酯 | CAS号1679-55-6 5,5-dimethyloxa... | CAS号4830-05-1 3,3-二甲基-四氢-吡喃-2-酮 | CAS号279692-23-8 4-(4,4-二甲基-2,6-...

2,2-二甲基戊二酸置于tetrabutylammonium Rhodanide体系中,用 乙腈 用作溶剂,以52%的收率获得2,2-二甲基戊二酸酐
参考文献:二元酸电化学脱水成环酸酐
标题:二元酸电化学脱水成环酸酐
摘要:提出了二羧酸与其环状酸酐的电化学脱水反应.电化学产生的酸酐可直接用于酰胺化反应.通过18 O 同位素标记研究了反应机理,揭示了电解过程中硫酸盐的形成.
Doi:10.1002/chem.202400403

专利信息

专利号:US-2025115551-A1
优先权日:2023-10-03
标 题:Synthesis of ras inhibitors
发明人：LI YI; MENDOZA BENJAMIN; NAGANATHAN SRIRAM; WANG ROSS; YI YI; BALLMER STEVEN G; DAVIDSON JAMES; HUANG XIAOJUN
权利人:REVOLUTION MEDICINES INC
摘要:The present invention relates to Ras inhibitors, intermediates in the synthesis thereto, and methods for preparing the Ras inhibitors and the intermediates.

专利号:US-2003203915-A1
优先权日:2002-04-05
标题 :Nitric oxide donors, compositions and methods of use related applications
发明人：FANG XINQIN; GARVEY DAVID S; GASTON RICKY D; LIN CHIA-EN; RANATUNGA RAMANI R; RICHARDSON STEWART K; WANG TIANSHENG; WANG WEIHENG; WEY SHIOW-JYI
权利人:FANG XINQIN; GARVEY DAVID S; GASTON RICKY D; LIN CHIA-EN; RANATUNGA RAMANI R; RICHARDSON STEWART K; WANG TIANSHENG; WANG WEIHENG; WEY SHIOW-JYI
摘要:The invention describes novel nitric oxide donors and novel compositions comprising at least one nitric oxide donor. The invention also provides novel compositions comprising at least one nitric oxide donor, and, optionally, at least one therapeutic agent. The compounds and compositions of the invention can also be bound to a matrix. The invention also provides methods for treating cardiovascular diseases, for the inhibition of platelet aggregation and platelet adhesion caused by the exposure of blood to a medical device, for treating pathological conditions resulting from abnormal cell proliferation; transplantation rejections, autoimmune, inflammatory, proliferative, hyperproliferative, vascular diseases; for reducing scar tissue or for inhibiting wound contraction, particularly the prophylactic and/or therapeutic treatment of restenosis by administering the nitric oxide donor optionally in combination with at least one therapeutic agent. The invention also provides methods for treating inflammation, pain, fever, gastrointestinal disorders, respiratory disorders and sexual dysfunctions. The nitric oxide donors donate, transfer or release nitric oxide, and/or elevate endogenous levels of endothelium-derived relaxing factor, and/or stimulate endogenous synthesis of nitric oxide and/or are substrates for nitric oxide synthase and are capable of releasing nitric oxide or indirectly delivering or transferring nitric oxide to targeted sites under physiological conditions. The therapeutic agent can optionally be substituted with at least one NO and/or NO 2 group (i.e., nitrosylated and/or nitrosated). The invention also provides novel compositions and kits comprising at least one nitric oxide donor and/or at least one therapeutic agent.

专利号:US-8138272-B2
优先权日:2006-05-22
标 题:Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds
发明人：KONRADI ANDREI W; SMITH JENIFER L
权利人:KONRADI ANDREI W; SMITH JENIFER L; ELAN PHARM INC
摘要:This invention provides an improved synthesis of polymer conjugates of formula (I), n nof agricultural, therapeutic, and food additive compounds. In particular, a process is described for the preparation of conjugates by treating primary or secondary alcohol substituents of active compounds with polymeric nucleophiles using “Mitsunobuâ€? or related reaction conditions.

专利号:WO-2025124564-A1
优先权日:2023-12-15
标题:Polyester synthesis based on aspartic acid modification
发明人：ZHANG KECHUN; CHEN XI; LEI TENGFEI; LIU SHENGYANG
权利人:MINT BIOTECHNOLOGIES CO LTD
摘要:Provided in the present invention is polyester synthesis based on aspartic acid modification. A monomer of a unique structure of an imide ring is obtained based on aspartic acid and a dibasic acid likely to be cyclized, the monomer is based on the aspartic acid, can be derived from biomass, is low in cost and renewable, meets the requirement of sustainable development, and the unique structure of the monomer can regulate and control various properties of polyester materials, such as the mechanics, temperature resistance, hydrophilicity and hydrophobicity, and crystallization.

专利号:US-6326372-B1
优先权日:1999-09-30
标 题:Lactam and cyclic urea derivatives useful as alpha 1a adrenoceptor antagonists
发明人：EVANS BEN E; GILBERT KEVIN F
权利人:MERCK & CO INC
摘要:Lactam and cyclic urea derivatives and their pharmaceutically acceptable salts are disclosed. The synthesis of these compounds and their use as alpha 1a adrenergic receptor antagonists is also described. One application of these compounds is in the treatment of benign prostatic hyperplasia. These compounds are typically selective in their ability to relax smooth muscle tissue enriched in the alpha 1a receptor subtype without at the same time inducing hypotension. One such tissue is found surrounding the urethral lining. Therefore, one utility of the instant compounds is to provide acute relief to males suffering from benign prostatic hyperplasia, by permitting less hindered urine flow. Another utility of the instant compounds is provided by combination with a human 5-alpha reductase inhibitory compound, such that both acute and chronic relief from the effects of benign prostatic hyperplasia can be achieved.

专利号:US-2024383920-A1
优先权日:2023-04-14
标 题:Synthesis of ras inhibitors
发明人：LI SHAOLING; LL YI; LOBBEN PAUL; WANG ROSS; BALLMER STEVE; HUANG XIAOJUN
权利人:REVOLUTION MEDICINES INC
摘要:The present invention relates to Ras inhibitors and to methods for preparing Ras inhibitors.