CAS: 86404-04-8; (R)-5-((S)-1,2-Dihydroxyethyl)-4-Ethoxy-3-Hydroxyfuran-2(5H)-One

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CAS号86404-03-7 5,6-O-isopropyl... | CAS号74-96-4 溴乙烷 | CAS号50-81-7 抗坏血酸 | CAS号62-50-0 甲磺酸乙酯 | CAS号64-67-5 硫酸二乙酯 | CAS号15042-01-0 5,6-O-异丙叉基-L-抗坏血酸

维生素 C置于aluminum (Iii) Chloride,水,碳酸氢钠,N-Bromopyrrolidine体系中,用 乙醚,乙醇 作为反应溶剂,化学反应 32.0H,反应生成 维生素c乙基醚
参考文献:一种维生素c乙基醚的制备方法
标题:一种维生素c乙基醚的制备方法
摘要:本发明属于药物合成技术领域,具体涉及一种维生素c乙基醚的制备方法.所述方法包括以下步骤:维生素c,含氮卤化剂和路易斯酸试剂混合后加热反应后经减压干燥处理得到溴化维生素c;溴化维生素c经,溴乙烷和三乙胺按照摩尔比1:0.3~0.5:1混合溶解于乙醚中,加热至60~80oc反应12~18H后,减压蒸馏得到维生素c醚化物;维生素c醚化物溶解于去离子水中,加入弱碱试剂后加热至30~40oc后反应6~8H,减压蒸干得到维生素c乙基醚.本发明通过在维生素c的5位和6位羟基形成低位阻的卤代保护基团,再对维生素c的3位羟基进行醚化,最后通过碱性环境下水解去除卤代保护基团,得到维生素c乙基醚,提高了维生素c乙基醚的产率,拓展了维生素c乙基醚的制备方法.

专利信息

专利号:WO-2024080290-A1
优先权日:2022-10-12
标 题 :Melanin pigment synthesis inhibitor
发明人：FUJITA YUKIKO; KOJIMA HIROYUKI; NAKAMURA NORIYUKI; ARUNASIRI IDDAMALGODA
权利人:ICHIMARU PHARCOS INC
摘要:The present invention provides a new composition or the like for use on the skin of a human or the like and for preventing deterioration in skin functions.　This melanin pigment synthesis inhibitor comprises (a) tranexamic acid, (b) a nicotinic acid amide, (c) glutathione, (d) a vitamin C derivative, and (e) sodium pyrosulfite.

专利号:US-2009232915-A1
优先权日:2008-03-14
标 题 :Mixtures with a collagen synthesis boosting action
发明人：SCHMAUS GERHARD; FRANKE HELGE; LANGE SABINE
权利人:SYMRISE GMBH & CO KG
摘要:The invention relates to synergistically active, ternary mixtures which boost collagen synthesis and to the uses thereof, in particular for slowing down skin ageing and for wound healing of damaged skin. The invention furthermore relates to the use of the ternary mixtures according to the invention for treating the oral cavity and pharynx, and in particular therein for preventing and slowing down periodontitis, for building up periodontal connective tissue and for preventing and treating infections in the oral cavity and for wound healing in the oral cavity.

专利号:WO-2020158831-A1
优先权日:2019-01-30
标 题:Transdermal absorption composition with controlled release of water-soluble hydrochloride
发明人：ONO FUMIYASU; GOTO MASAHIRO
权利人:UNIV KYUSHU NAT UNIV CORP; NISSAN CHEMICAL CORP
摘要:The objective of the present invention is to provide a method for simply raising the transdermal absorption properties of a water-soluble hydrochloride without forming a prodrug by organic synthesis.　The present invention relates to: a composition containing a water-soluble hydrochloride and a liposoluble compound having an aldehyde group; a transdermal absorption composition containing said composition, a transdermal absorption control agent, and a liposoluble medium; and a method for controlling the release of the water-soluble hydrochloride from the composition into the skin.

专利号:US-9567368-B2
优先权日:2013-11-29
标 题:Peptide tyrosinase activators
发明人：HANTASH BASIL M; UBEID ANAN ABU
权利人:ESCAPE THERAPEUTICS INC
摘要:Peptides that increase melanin synthesis are provided. These peptides include pentapeptides YSSWY (SEQ ID NO: 1), YRSRK (SEQ ID NO: 2), and their variants. The peptides may activate the enzymatic activity of tyrosinase to increase melanin synthesis. The pharmaceutical, cosmetic, and other compositions including the peptides are also provided. The methods of increasing melanin production in epidermis of a subject are provided where the methods include administering compositions comprising an amount of one or more peptides effective to increase the melanin production. The methods also include treating vitiligo or other hypopigmentation disorders with compositions including one or more peptides.

专利号:ES-2400284-T3
优先权日:2008-03-14
标题 :Mixes with a stimulating action of collagen synthesis

专利号:US-8361516-B2
优先权日:2006-08-03
标 题:Composition comprising sarsasapogenin
发明人：LINTNER KARL; MAS CHAMBERLIN CLAIRE
权利人:SEDERMA SA; LINTNER KARL; MAS CHAMBERLIN CLAIRE
摘要:The présent invention relates to a composition comprising sarsasapogenin or a plant extract containing it in order to improve the gêneral state of the skin and in particular to improve and/or embellish any part of the body showing a déficit in lipids. More particularly, the invention is directed to a cosmetic method to improve the figure, comprising the step of topically applying to the skin a cosmetic or dermopharmaceutical composition comprising sarsasapogenin to favour the expansion and/or the formation of the subcutaneous adipose tissue, and/or to favour the lipid synthesis in the epidermis.