CAS: 13775-80-9; Hydrazine Hydrobromide

该化合物是一种稳定,晶状的氢氰化物衍生物,通常用作有机合成中的减少剂和中间体,其主要优点包括在还原变异中具有高度的回反应性,特别是在制药和细化化学品方面.该化合物与免费的氢氰化物相比,提高了处理和储存稳定性,降低了与挥发性相关的安全风险.其定义明确的异构测量法确保碳基减少和异氧循环形成等反应的一贯性能.Hydrazine单氢溴化物还用于分析化学,以追踪金属检测.氢溴化物盐形式提高了极溶剂的溶性,促进了合成应用中的受控反应条件.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

bromine hydrogen bromidepotassium bromide hydrogen azide nitrogen ammonia

合成工艺路线路线简述

    Hydrazonium Dibromide 反应生成氢溴酸肼
    参考文献:Christensen,B. E.; Gilbert,C.,Journal Of The American Chemical Society,1934,Vol. 56,P. 1808
    标题:Christensen,B. E.; Gilbert,C.,Journal Of The American Chemical Society,1934,Vol. 56,P. 1808

    专利信息


    专利号:WO-9805658-A1
    优先权日:1996-08-07
    标 题 :Synthesis of 2-(2-furoyl)-4(5)-(2-furanyl)-1h-imidazole and analogs thereof
    发明人:RHO TAIKYUN; LANKIN MICHAEL E; SHIH DAVID H; LANKIN CLAIRE M
    权利人:ALTEON INC
    摘要:The present invention relates to a practical and facile synthesis of 2-(2-furoyl)-4(5)-(2-furanyl)-1H-imidazole (FFI) and analogs thereof. The synthesis utilizes a novel hydrazinium salt as an intermediate reaction product which facilitates the isolation of purified product in high yields.

    专利号:US-5856511-A
    优先权日:1996-08-07
    标题 :Synthesis of 2-(2-furoyl)-4(5)-(2-furanyl)-1H-imidazole and analogs thereof
    发明人:RHO TAIKYUN; LANKIN MICHAEL E; SHIH DAVID H; LANKIN CLAIRE M
    权利人:ALTEON INC
    摘要:The present invention relates to a practical and facile synthesis of 2-(2-furoyl)-4(5)-(2-furanyl)-1H-imidazole (FFI) and analogs thereof. The synthesis utilized a novel hydrazinium salt as an intermediate reaction product which facilitates the isolation of purified product in high yields.

    专利号:US-10654862-B2
    优先权日:2015-03-18
    标题 :Methods for the chemical synthesis of pyrrole-linked bivalent compounds, and compositions thereof
    发明人:CRAN JOHN
    权利人:AVEKSHAN LLC
    摘要:The present invention in various aspects relates to the synthesis of pyrrole-linked bivalent compounds, including but not limited to norBNI, as well as pharmaceutical compositions comprising the same.

    专利号:US-4013658-A
    优先权日:1975-07-03
    标 题 :Synthesis of 3,5-diphenyl-4(1h)-pyridazinones
    发明人:ABDULLA RIAZ F
    权利人:LILLY CO ELI
    摘要:A series of 3,5-diphenyl-4(1H)-pyridazinones are synthesized by a two-step process, both steps of which are new. In the first step, a phenylglyoxyloyl halide is reacted with a styrylamine in the presence of a base to form a 1-amino-2,4-diphenyl-1-buten-3,4-dione. In the second step, the enaminoketone formed in the first step is reacted with hydrazine or an alkylhydrazine to form the pyridazinone. Both steps of the reaction proceed in good yields at temperatures in the range of from about 0° C. to about 40° C. in the common reaction solvents.

    专利号:JP-H09510693-A
    优先权日:1993-12-28
    标题:Modular design and synthesis of amine-imide containing molecules

    专利号:US-10253034-B2
    优先权日:2015-03-18
    标题:Methods for the chemical synthesis of pyrrole-linked bivalent compounds, and compositions thereof
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    合成参考文献


    摘要:Compound: Hydrazine, hydrobromide (1:1)
    摘要:Compound: Hydrazine, hydrobromide (1:2)
    摘要:Rück-Braun, K.; Freysoldt, T., Science of Synthesis, (2007) 35, 535.
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