CAS: 483-04-5; Raubasine

上下游产品

CAS号67-56-1 甲醇 | CAS号5815-08-7 叔丁氧基双(二甲胺基)甲烷 | CAS号483-03-4 3-Isoajmalicine | CAS号19351-63-4 断马钱子苷

3-Dehydroajmalicine Perchlorate置于三正丁基氢锡体系中,用 甲醇 作为反应溶剂,化学反应 0.08H,以90%的收率获得产物萝巴新
参考文献:A Mild And Chemoselective Reduction Of Cyclic Iminium Salts
标题:A Mild And Chemoselective Reduction Of Cyclic Iminium Salts
摘要:在室温下,通过与甲醇中的三丁基锡烷反应,N-取代环状亚胺盐可以方便地还原成相应的叔胺,而且收率很高.在这些条件下,分子中存在的各种官能团(如酮基)不会受到影响.
DOI:10.1055/s-1985-31434

专利信息

专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

专利号:US-10814013-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

专利号:US-2008107598-A1
优先权日:2006-10-05
标 题:Efficient Synthesis of Chelators for Nuclear Imaging and Radiotherapy: Compositions and Applications

专利号:EP-2079486-A2
优先权日:2006-10-05
标题:Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

专利号:US-2013039853-A1
优先权日:2006-10-05
标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

专利号:CN-101678118-A
优先权日:2006-10-05
标 题:Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications