CAS: 693-54-9; Decan-2-One

相似化合物

33758-15-5 111-13-7 112-12-9

上下游产品

CAS号872-05-9 正癸烯 | CAS号764-93-2 1-癸炔 | CAS号1120-06-5 2-癸醇 | CAS号31637-05-5 2-methyl-2-°Cty... | CAS号3695-29-2 5-iodopentan-2-one | CAS号6393-56-2 正戊基氯化镁 | CAS号122-39-4 二苯胺 | CAS号111-66-0 1-辛烯 | CAS号106094-59-1 N-[(Z)-decan-2-... | CAS号21078-68-2 3-Undecanol, 3-... | CAS号105-21-5 丙位庚内酯 | CAS号104-50-7 丙位辛内酯 | CAS号3128-06-1 5-氧代己酸 | CAS号123-76-2 乙酰丙酸 | CAS号3128-07-2 5-乙酰戊酸 | CAS号1117-74-4 4-氧代-己酸 | CAS号111-66-0 1-辛烯 | CAS号824-58-8 Ethanone, 1-bic...

十一碳-2-炔酸置于air,[au(Dpb)Sbf6]2(Cod)体系中,用 1,2-二氯乙烷 作为反应溶剂,化学反应 24.0H,反应生成 2-癸酮
参考文献:具有 L2/z 型二膦硼烷配体的炔衍生物的金催化形式水合,脱羧和 [4+2] 环加成
标题:具有 L2/z 型二膦硼烷配体的炔衍生物的金催化形式水合,脱羧和 [4+2] 环加成
摘要:使用以 Z 配体为特征的 Au 催化剂开发了炔烃的催化形式水合和炔酸的脱羧.此外,Al的分子内[4+2]环加成...
DOI:10.1246/cl.180610

专利信息

专利号:WO-2008115912-A1
优先权日:2007-03-21
标题:Regio-specific synthesis of 4-bromo-3-methyl-5-propoxy-thiophene-2-carboxylic acid
发明人：KUBIAK GREGORY G; LYTHGOE DAVID J; YU YONG
权利人:SANOFI AVENTIS; KUBIAK GREGORY G; LYTHGOE DAVID J; YU YONG
摘要:This invention is directed to a five step regio-specific synthesis of 4-bromo-3-methyl-5-propoxy-thiophene-2-carboxylic acid compound of formula 16 comprising the steps of acetalating 3-methyl-thiophene-2-carbaldehyde in an alcohol solvent; iodinating the acetalated 3-methyl-thiophene-2-carbaldehyde in an non-protic polar or hydrocarbon solvent to yield the corresponding iodinated and acetalated 3-methyl-thiophene-2-carbaldehyde product; treating the iodinated and acetalated product with water to yield the corresponding 5-iodo-3-methyl-thiophene-2-carbaldehyde; oxidizing the 5-iodo-3-methyl-thiophene-2-carbaldehyde to the corresponding 5-iodo-3-methyl-thiophene-2-carboxylic acid in ketone solvent; Ullmann coupling of the 5-iodo-3-methyl-thiophene-2-carboxylic acid with alkali metal propoxide salt using a copper catalyst in propanol to yield 3-methyl-5-propoxy-thiophene-2-carboxylic acid; esterifying 3-methyl-5-propoxy-thiophene-2-carboxylic acid to yield the corresponding alkyl 3-methyl-5-propoxy-thiophene-2-carboxylate; brominating the 3-methyl-5-propoxy-thiophene-2-carboxylic acid to yield the corresponding alkyl 4-bromo-3-methyl-5-propoxy-thiophene-2-carboxylate; and basic hydrolyzing the alkyl 4-bromo-3-methyl-5-propoxy-thiophene-2-carboxylate with base to yield 4-bromo-3-methyl-5-propoxy-thiophene-2-carboxylic acid.

专利号:US-9085538-B2
优先权日:2010-07-26
标题:Process for the preparation of key intermediates for the synthesis of statins or pharmaceutically acceptable salts thereof
发明人：CASAR ZDENKO; STERK DAMJAN; JUKIC MARKO
权利人:CASAR ZDENKO; STERK DAMJAN; JUKIC MARKO; LEK PHARMACEUTICALS
摘要:The invention relates to commercially viable process for the synthesis of key intermediates for the preparation of statins, in particular Rosuvastatin and Pitavastatin or respective pharmaceutically acceptable salts thereof. A new simple and short synthetic route for key intermediates is presented which benefits from the use of cheap and readily available starting materials, by which the conventionally most frequently used DIBAL-H as reducing agent can be avoided.

专利号:US-10040752-B2
优先权日:2015-08-24
标 题 :Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof
发明人：MKRTCHYAN GNEL; YAO QINGWEI
权利人:CODY LABORATORIES INC
摘要:Highly efficient methods for synthesis of levomethadone hydrochloride or dextromethadone hydrochloride are provided starting from D-alanine, or L-alanine, respectively, with retention of configuration. Methods for treating a subject are provided comprising administering a composition comprising an effective amount of levomethadone hydrochloride having not more than 10 ppm dextromethadone.

专利号:EP-2173747-B1
优先权日:2007-06-26
标 题:A regioselective metal catalyzed synthesis of annelated benzimidazoles and azabenzimidazoles
发明人：ALONSO JORGE; LINDENSCHMIDT ANDREAS; NAZARE MARC; R KYEN OMAR; URMANN MATHIAS; HALLAND NIS
权利人:SANOFI SA
摘要:The present invention relates to a process for the regioselective synthesis of compounds of the formula I, wherein R1; R2; R3; R4; J1; J2; J3; J4 and G have the meanings indicated in the claims. The present invention provides a direct metal, e.g. palladium or copper, catalyzed, regioselective process to a wide variety of unsymmetrical, multifunctional N-substituted benzimidazoles or azabenzimidazoles of formula I starting from 2-halo-nitroarenes and N-substituted amides.

专利号:US-5681978-A
优先权日:1993-07-07
标题:Method for the stereocontrolled synthesis of stegobinone and useful borane intermediates
发明人：MATTESON DONALD S; MAN HON-WAH; HO OLIVER
权利人:UNIV WASHINGTON
摘要:A method of synthesis of (2S,3R,1'R)-stegobinone(I) using borane intermediates and methods for the use of stegobinone (I) for attracting beetles of the Anobium species.

专利号:US-9096519-B2
优先权日:2013-01-10
标 题 :Process for the synthesis of ketones from internal alkenes
发明人：MORANDI BILL; GRUBBS ROBERT H; WICKENS ZACHARY K; LERCH MICHAEL M
权利人:CALIFORNIA INST OF TECHN
摘要:The present invention is directed to methods for oxidizing internal olefins to ketones. In various embodiments, each method comprising contacting an organic substrate, having an initial internal olefin, with a mixture of (a) a biscationic palladium salt; and (b) an oxidizing agent; dissolved or dispersed in a solvent system to form a reaction mixture, said solvent system comprising at least one C 2-6 carbon nitrile and optionally at least one secondary alkyl amide, said method conducted under conditions sufficient to convert at least 50 mol % of the initial internal olefin to a ketone, said ketone positioned on a carbon of the initial internal olefin. The transformation occurs at room temperature and shows wide substrate scope. Applications to the oxidation of seed oil derivatives and a bioactive natural product are described.