CAS: 4592-94-3; 3-(4-Bromophenyl)-3-Oxopropanenitrile

上下游产品

CAS号5798-75-4 4-溴苯甲酸乙酯 | CAS号75-05-8 乙腈 | CAS号18293-53-3 (三甲硅基)乙腈 | CAS号201230-82-2 carbon monoxide | CAS号589-87-7 对溴碘苯 | CAS号873-75-6 4-溴苄醇 | CAS号151-50-8 氰化钾 | CAS号99-73-0 对-α-二溴苯乙酮 | CAS号57-12-5 cyanide | CAS号6048-21-1 4-溴苯甲酰氰 | CAS号5053-63-4 3-氨基-1-苯基丙烷-1-醇 | CAS号78583-82-1 3(4-溴苯)-1H-5-氨基吡唑 | CAS号52200-18-7 2-[(二甲基氨基)亚甲基]-... | CAS号74101-15-8 1H-Pyrazol-5-am... | CAS号74101-27-2 N-[5-(4-bromoph... | CAS号65984-53-4 3-(4-溴苯基)丙-1-胺 | CAS号914644-25-0 N-[3-(4-bromobe... | CAS号618091-10-4 (5-AMINO-1-PHEN...

3-(4-Bromophenyl)-3-Chloroprop-2-Enal置于ammonium Hydroxide,碘,Sodium Hydroxide体系中,用 二氯甲烷,水,二甲基亚砜 作为反应溶剂,化学反应 0.75H,反应生成 4-溴苯甲酰乙腈
参考文献:致命的kcn和昂贵的无金属轨道,使用温和的反应条件即可获得β-酮腈
标题:致命的kcn和昂贵的无金属轨道,使用温和的反应条件即可获得β-酮腈
摘要:摘要 已经描述了使用温和的反应条件,使用经济上良性的碘,氨水和氢氧化钠溶液从易于获得的3-氯丙烯一锅合成β-乙腈.该报告提出了一种便捷,廉价,无毒无害,环保的β-乙腈方法.
DOI:10.1080/00397911.2021.1910846

专利信息

专利号:US-2022204495-A1
优先权日:2019-05-03
标题:Inhibiting trabid
发明人：CAMPBELL ANNE-MARIE; MARCIN Lawrence; KAYSER-BRICKER KATHERINE
权利人:VALO HEALTH INC; INTEGRAL HEALTH HOLDINGS LLC
摘要:The present disclosure is directed to compounds of formulas (I)-(VII), which are useful as modulators of TRABID. The compounds are further useful in the inhibition of TRABID and the treatment of diseases or disorders associated with the inhibition of TRABID. For instance, the disclosure is concerned with compounds and compositions for inhibition of TRABID, methods of treating diseases associated with the inhibition of TRABID (e.g., autoimmune inflammatory diseases including, but not limited to, psoriasis), and methods of synthesis of these compounds.

专利号:CN-114057666-A
优先权日:2020-08-04
标 题:Synthesis method of 4, 5-disubstituted-2-aminothiazole compound