CAS: 707-07-3; (Trimethoxymethyl)Benzene

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CAS号67-56-1 甲醇 | CAS号1125-88-8 苯甲醛二甲缩醛 | CAS号93-58-3 苯甲酸甲酯 | CAS号108-88-3 甲苯 | CAS号124-41-4 甲醇钠 | CAS号98-07-7 三氯甲苯 | CAS号7471-86-5 苯亚胺酸甲酯 | CAS号100-47-0 苯甲腈 | CAS号5873-90-5 苯亚氨基酸甲酯盐酸盐 | CAS号108-86-1 溴苯 | CAS号111456-85-0 1-[dimethoxy(ph... | CAS号3336-65-0 2-[氨基(苯基)亚甲基]丙二腈 | CAS号92-71-7 2,5-二苯基噁唑 | CAS号2236-57-9 [Ethoxy(methoxy... | CAS号833-50-1 2-苯基苯并恶唑 | CAS号95-54-5 邻苯二胺(OPD) | CAS号716-79-0 2-苯基苯并咪唑 | CAS号1741-50-0 5-溴-2-苯基-苯并咪唑 | CAS号1260750-72-8 5-iodo-2-phenyl... | CAS号2834-10-8 2-Methoxybenzyl...

专利信息

专利号:US-6849743-B2
优先权日:1997-08-15
标 题 :Synthesis of clasto-lactacystin β-lactone and analogs thereof
发明人：SOUCY FRANCOIS; FLAMONDON LOUIS; BEHNKE MARK; ROUSH WILLIAM
权利人:MILLENNIUM PHARM INC
摘要:The present invention is directed to an improved synthesis of clasto-lactacystin-β-lactone, and analogs thereof, that proceeds in fewer steps and in much greater overall yield than syntheses described in the prior art. The synthetic pathway relies upon a novel stereospecific synthesis of an oxazoline intermediate and a unique stereoselective addition of a formyl amide to the oxazoline. Also described are novel clasto-lactacystin-β-lactones, and analogs thereof and their use as proteasome inhibitors.

专利号:US-2007260076-A1
优先权日:2003-12-05
标 题:Practical, Cost-Effective Synthesis of Ubiquinones
发明人：LIPSHUTZ BRUCE H; BERL VOLKER; SHEIN KARIN; WETTERICH FRANK
权利人:LIPSHUTZ BRUCE H; BERL VOLKER; SHEIN KARIN; WETTERICH FRANK
摘要:The present invention provides a convergent method for the synthesis of ubiquinones and ubiquinone analogues. Also provided are precursors of ubiquinones and their analogues that are useful in the methods of the invention. The invention further provides an improved method for the carboalumination of alkyne substrates.

专利号:US-2006167289-A1
优先权日:2003-12-05
标题 :Practical, cost-effective synthesis of ubiquinones
发明人：LIPSHUTZ BRUCE H; BERL VOLKER; SCHEIN KARIN; WETTERICH FRANK
权利人:ZYMES LLC
摘要:The present invention provides a convergent method for the synthesis of ubiquinones and ubiquinone analogues. Also provided are precursors of ubiquinones and their analogues that are useful in the methods of the invention. The invention further provides an improved method for the carboalumination of alkyne substrates.

专利号:US-2008039642-A1
优先权日:2004-09-23
标题 :Practical, Cost-Effective Synthesis of Chloromethylated 1, 4-Benzoquinones
发明人：BERL VOLKER; WETTERICH FRANK; ERNST HANSGEORG; SCHEIN KARIN
权利人:BERL VOLKER; WETTERICH FRANK; ERNST HANSGEORG; SCHEIN KARIN
摘要:The present invention relates to a practical and cost-effective method for the synthesis of 5-chloromethylated 2,3-dialkoxy-6-alkyl-1,4-benzoquinones by direct chloromethylation of the corresponding 2,3-dialkoxy-6-alkyl-1,4-benzoquinones. The invention further relates to a method for the preparation of 5-chloromethylated 2,3-dialkoxy-6-alkyl-1,4-benzoquinones starting from a 3,4,5-trialkoxy-1-alkyl-benzene. The invention also relates to a method for the production of Coenzymes Q n , especially coenzyme Q 10 .

专利号:US-2014323705-A1
优先权日:2011-05-13
标题:Manufacture of lacto-n-tetraose
发明人：HEDEROS MARKUS; DEKANY GYULA; DEMKÓ SÃ?NDOR; Kovács Imre; BAJZA ISTVÃ?N
权利人:HEDEROS MARKUS; DEKANY GYULA; DEMKÓ SÃ?NDOR; Kovács Imre; BAJZA ISTVÃ?N
摘要:The present invention relates to the synthesis of the tetrasaccharide of formula (I) and novel intermediates used in the synthesis.

专利号:US-11976081-B2
优先权日:2019-04-26
标题 :Intermediate of eribulin and synthesis method and use thereof
发明人：XU WEIPING
权利人:BEIJING TIENYI LUFU PHARMATECH CO LTD
摘要:An intermediate compound is prepared and used for the synthesis of halichondrin B, eribulin or an analog thereof, particularly a structural fragment C27-C35 thereof. The starting materials of the synthetic route are readily available, and the optical purity of the starting materials can be ensured, so that the optical purity of the structural fragment C27-C35 in halichondrin B, eribulin or the analog thereof is ensured. Steps for constructing a chiral center of the structural fragment C27-C35 feature higher diastereoselectivity and yield, in particular preparation methods of compounds of formulae (X), (XI), (XVI) and (XV). By-products of partial reactions can be removed only by recrystallization, which results in easy purification and significant reduce in cost.