CAS: 204841-19-0; 3-Acetylphenylboronic Acid

上下游产品

3-异丙基苯硼酸 3-Isopropylphenylboronic Acid 216019-28-2
3-(1-羟乙基)苯基硼酸 3-(1-Hydroxyethyl)Phenylboronic Acid 1036760-03-8
3-乙炔基-苯硼酸 (3-Ethynylphenyl)Boronic Acid 1189127-05-6

3-异丙基苯硼酸置于iron(III) Trifluoromethanesulfonate,间氯过氧苯甲酸体系中,用 水,乙腈 用作溶剂,以62%的收率获得3-乙酰基苯硼酸
参考文献:一种铁催化苄位叔碳断键氧化合成芳酮的方法
标题:一种铁催化苄位叔碳断键氧化合成芳酮的方法
摘要:本发明公开了一种铁催化苄位叔碳断键氧化合成芳酮的方法,以有机溶剂和水溶液用作溶剂,在氧化剂的作用下,催化氧化苄位叔碳合成芳酮,反应通式表示如下.本发明使用廉价绿色的铁催化剂,在绿色氧化剂过氧化氢作用下,以乙腈和水用作溶剂,将苄位叔碳断键氧化成羰基生成相应的芳酮.本发明催化氧化反应制备芳酮的方法,使用环境友好的廉价金属催化剂和氧化剂,而且反应底物廉价易得性质稳定,具有较好的官能团相容性.在优化的反应条件之下,目标产品分离收率高达96%.

专利信息

专利号:US-2010022541-A1
优先权日:2006-09-25
标题:Chemical inhibitors of bacterial heptose synthesis, methods for their preparation and biological applications of said inhibitors
发明人：ESCAICH SONIA; DENIS ALEXIS; MOREAU FRANCOIS; GERUSZ VINCENT; DESROY NICOLAS
权利人:ESCAICH SONIA; DENIS ALEXIS; MOREAU FRANCOIS; GERUSZ VINCENT; DESROY NICOLAS
摘要:The invention relates to new compounds having heptose synthesis inhibitory properties, of formula (I) or a pharmaceutically acceptable salt, or prodrug thereof, wherein A is an aryl or heterocycle, optionally substituted by one or several identical or different R such as H, C1-C10 alkyl, C1-C10 alkyl-OR 1 , C1-C10 alkyl-NR 1 R 1 , alkoxy, hydroxy, thioalkyl, aryl, heterocycle, halogen, nitro, cyano, CO 2 R 1 , NR 1 R 1 , NR 1 C(O)R 1 , C(O)NR 1 R 1 , NR 1 C(S)R 1 , C(S)NR 1 R 1 , SO 2 NR 1 R 1 , SO 2 R 1 , NR 1 SO 2 R 1 , NR 1 C(O)NR 1 R 1 , NR 1 C(O)OR 1 , NR 1 C(S)NR 1 R 1 , NR 1 C(S)OR 1 , R 1 Câ•?NOR 1 , C(O)R 1 , aryloxy, thioaryl, alkenyl, alkynyl R1 identical or different is H or C1-C10 alkyl B 1 , B 2 , B 3 identical or not represent C, N, O, S to form a five-membered aromatic ring wherein from one to three carbon atoms are replaced by a heteroatom selected from S, O, N optionally substituted by one or several identical or different R such as defined above B 4 is C or N Y is H, C1-C10 alkyl, alkoxy, thio-alkyl, optionally substituted by one or several identical or different R such as defined above W is C, O or N, substituted or not by one or several C1-C10 alkyl radicals D is an heterocycle optionally substituted by one or several identical or different R such as defined aboe.

专利号:US-2022298116-A1
优先权日:2019-07-04
标题:Process for the preparation of key intermediates for the synthesis of eltrombopag or salt thereof

专利号:CN-117720447-A
优先权日:2023-11-22
标题 :A method for rhodium-catalyzed synthesis of 1,3-N,S compounds

专利号:BR-PI0711208-A2
优先权日:2006-05-19
标 题 :compounds, intermediates for the synthesis of compounds, process, pharmaceutical composition, use of a compound and uses

专利号:US-7250410-B2
优先权日:2001-06-07
标题:Cyclic nucleotide phosphodiesterase inhibitors, preparation and uses thereof
发明人：BOURGUIGNON JEAN-JACQUES; LAGOUGE YAN; LUGNIER CLAIRE; KLOTZ EVELINE; MACHER JEAN-PAUL; RABOISSON PIERRE; SCHULTZ DOMINIQUE
权利人:VIA PHARMACEUTICALS INC
摘要:The invention concerns novel benzodiazepine derivatives and their uses in the field of therapeutics particularly for treating pathologies involving the activity of a cyclic nucleotide phosphodiesterase. It also concerns methods for preparing them and novel synthesis intermediates. The inventive compounds more particularly correspond to general formula (I):

专利号:AU-2007301607-A1
优先权日:2006-09-25
标 题 :Substituted heterocyclylcarbonylamino-acetic-acid-derivatives as inhibitors of bacterial heptose synthesis, methods for their preparation and biological applications of said inhibitors