CAS: 14221-01-3; Tetrakis(Triphenylphosphine)Palladium

上下游产品

palladium diacetate triphenylphosphine palladium diacetate (0) chloroform complextris(dibenzylideneacetone)dipalladium(0) chloroform complexmethyl N-[(2S)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1H-imidazol-5-yl]phenyl]phenyl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate Triphenylphosphine oxide benzyl tert-butyl (2S,2'S)-2,2'-(4,4'-biphenyldiylbis(1H-imidazole-5,2-diyl))di(1-pyrrolidinecarboxylate) 4-biphenylacetonitrile

Dichloro[2-(β-Diphenylphosphinoethyl)Pyridine]Palladium(II)置于n(C2H5)3体系中,用 乙腈 用作溶剂,化学反应生成四(三苯基膦)钯
参考文献:Interaction Of Pdcl2-2-(β-Diphenylphosphine)Ethylpyridine Complex With Diols And Co: Synthesis Of New Alkoxycarbonyl Complexes,Key Intermediates To Cyclic Carbonates
标题:Interaction Of Pdcl2-2-(β-Diphenylphosphine)Ethylpyridine Complex With Diols And Co: Synthesis Of New Alkoxycarbonyl Complexes,Key Intermediates To Cyclic Carbonates
摘要:Pdcl2Pn (Pn) 2-(Beta-Diphenylphosphine) Ethylpyridine) Was Found To Be Effective In The Promotion Of The Alkoxycarbonylation Of Diols [(1,2-Hydroxyethane (He); 1,2-And 1,3-Hydroxypropane(1,2Hp,1,3Hp),1,2-,1,3-,And 1,4-Hydroxybutane (1,2Hb,1,3Hb,1,4Hb)]. The Relevant Mono-Alkoxycarbonyl Complexes Of The Diols,Of Formula Pdclpn(Coo-R-Oh),Were Isolated,Characterized In Solution,And Studied For Their Reactivity. All Complexes In The Presence Of Different Reagents Release The Alkoxycarbonyl Group Directly As Cyclic Carbonate Or As Chloroformate,Which "In Situ" Converts Into Cyclic Carbonate Or Other Valuable Carbonyl Products. The Structure Of The Complexes Pdcl[(Coo-Ch2-Ch2-Ch2(Oh)](Pn) (4C) And Pdcl(Coo-Ch2-Ch(Oh)-C2H5)(Pn) (4D) Was Also Derived By Single-Crystal X-Ray Diffraction.
Doi:10.1021/om060012E

专利信息

专利号:US-2016214860-A1
优先权日:2013-09-19
标题:Method of synthesis of unsolvated mixed cation borohydrides
发明人：JARON TOMASZ; WEGNER WOJCIECH; GROCHALA WOJCIECH
权利人:JAROÑ Tomasz; WEGNER WOJCIECH; GROCHALA WOJCIECH
摘要:The present invention relates to a novel method of synthesis of unsolvated mixed cation borohydrides of a general formula M x M′ y (BH 4 ) z , where M and M′ stand for metal cations, x, y, and z are stoichiometric coefficients. The method of synthesis according to the present invention is characterised in that the precursors having a general formula M[A n ] u and [Cat] v M′(BH 4 ) w are used for the synthesis, where [An] stands for a weakly coordinating anion; [Cat] stands for weakly coordinating cation; u, v, and w are the stoichiometric coefficients; and the synthesis is carried out under an inert to the reagents atmosphere—according to the general reaction equation: x M[An] u +y [Cat] v M′(BH 4 ) w →M x M′ y (BH 4 ) z +xu [Cat][An] where z=yw, xu=yv; M x M′ y (BH 4 ) z is the product of the reaction.

专利号:US-11465970-B2
优先权日:2017-12-14
标题 :Method for synthesis of Roxadustat and intermediate compounds thereof
发明人：XU YONGXIANG
权利人:NANJING CAVENDISH BIO ENGINEERING TECH CO LTD; XU YONGXIANG; NANJING CAVENDISH BIO ENG TECH CO LTD
摘要:The present application provides a method for synthesis of Roxadustat. A compound as represented by formula (VIII) is used as a raw material, and is reacted with phenol, a vinyl-containing ether, an acid, hydroxylamine, and then the product is reacted with glycine. In addition, the present application also provides intermediate compounds as represented by formula (IX), formula (XI), formula (XII), formula (IV), and formula (V) for synthesis of Roxadustat. Herein, details of the substituents involved in formula (VIII), formula (IX), formula (XI), and formula (XII) are stated in the description

专利号:US-11427530-B2
优先权日:2018-02-09
标 题 :Synthesis of 4-chlorokynurenines and intermediates
发明人：LEVIN DANIEL; LEEMING PETER; EISENREICH EMERICH; LIU XUEJUN KARL
权利人:VISTAGEN THERAPEUTICS INC
摘要:The invention relates to an overall enantio-specific synthesis of 4-chlorokynurenine compounds, in particular L-4-chlorokynurenine, with improved yields. Large-scale syntheses are disclosed. The invention also relates to novel intermediates in the synthesis of L-4-chlorokynurenine.

专利号:WO-2025215126-A1
优先权日:2024-04-12
标题:Synthesis of vidofludimus and its calcium salt
发明人：VITT DANIEL; IGLICAR PETRA; GEGE CHRISTIAN; Mühler Andreas; KOHLHOF HELLA; GRÖPPEL MANFRED
权利人:IMMUNIC AG
摘要:The invention relates to the process of preparation of 2-fluoro-4-(3-methoxyphenyl)aniline (3) as an intermediate. Said intermediate 2-fluoro-4-(3-methoxyphenyl)aniline (3) is obtained in a Suzuki coupling reaction from (3-methoxyphenyl)boronic acid (1) and 4-bromo-2-fluoro-aniline (2). The invention further relates to the synthesis of vidofludimus (5) from said intermediate 2-fluoro-4-(3-methoxy-phenyl)aniline (3) and from 1-cyclopentene-1,2-dicarboxylic anhydride (4). The invention further relates to the synthesis of vidofludimus calcium (6) from said vidofludimus (5) and from a calcium salt, preferably Ca(OH)2.

专利号:US-6350878-B1
优先权日:1998-05-18
标 题 :Intermediates for the synthesis of epothilones and methods for their preparation
发明人：ALTMANN KARL-HEINZ; BAUER ARMIN; SCHINZER DIETER
权利人:NOVARTIS AG
摘要:The invention relates to a method of synthesis for a compound of formula (I),wherein R is a heterocyclyl moiety and X1, X2, X3 and X4 are, independently of each other, protecting groups, which is appropriate for the synthesis of epothilone B and desoxyepothione B.

专利号:US-7148356-B2
优先权日:2001-07-13
标题:Process for the catalytic synthesis of biaryls and polymers from aryl compounds
发明人：SMITH III MILTON R; MALECZKA ROBERT E
权利人:UNIV MICHIGAN STATE
摘要:A process for producing organic substituted aromatic or heteroaromatic compounds including biaryl and biheteroaryl compounds in a two-step reaction. In the first step, the aromatic or heteroaromatic compound is borylated in a reaction comprising a borane or diborane reagent (any boron reagent where the boron reagent contains a B—H, B—B or B—Si bond) and an iridium or rhodium catalytic complex. In the second step, a metal catalyst catalyzes the formation of the organic substituted aromatic or heteroaromatic compound from the borylated compound and an electrophile such as an aryl or organic halide, triflate (OSO 2 CF 3 ), or nonaflate (OSO 2 C 4 F 9 ). The steps in the process can be performed in a single reaction vessel or in separate reaction vessels. The present invention also provides a process for synthesis of complex polyphenylenes starting from halogenated aromatic compounds.