28148-04-1 = 2163-42-0 + 93381-28-3 反应条件:1.1 Catalysts: Haloalkane Dehalogenase Solvents: Water; 90 Min,Ph 8.2,30 °C 标题:Haloalkane Dehalogenase Catalysed Desymmetrization And Tandem Kinetic Resolution For The Preparation Of Chiral Haloalcohols 作者:Westerbeek,Alja; Van Leeuwen,Jan G. E.; Szymanski,Wiktor; Feringa,Ben L.; Janssen,Dick B. 参考文献:Tetrahedron 日期:2012 卷标:68(37) 页码:7645-7650
2-亚甲基丙烷-1,3-二基二乙酸酯置于aluminum Nickel Sodium Methylate体系中,用 甲醇 用作溶剂,化学反应生成2-甲基-1,3-丙二醇 参考文献:Process For Preparing 2-Methylpropane-1,3-Diol 标题:Process For Preparing 2-Methylpropane-1,3-Diol 摘要:2-甲基丙烷-1,3-二醇是通过将2-甲烯基丙烷-1,3-二醇二乙酸酯与一种一元,低碳链醇在碱的存在下反应制备而成.随后,得到的2-甲烯基丙烷-1,3-二醇经催化氢化形成2-甲基丙烷-1,3-二醇.
专利号:US-2024368099-A1 优先权日:2022-01-18 标 题:Methods for the synthesis of di(hydroxymethyl)tetrahydrofuran and its application in polyesters and polyurethanes 发明人:SPIEGELBERG BRIAN; BRANDT ADRIAN; BECK HORST; KUX ALEXANDER; TIN SERGEY; DE VRIES JOHANNES GERARDUS 权利人:HENKEL AG & CO KGAA 摘要:The present invention relates to the synthesis of di(hydroxymethyl)tetrahydrofuran (DHMTHF) and the preparation of trans-enriched mixtures of DHMTHF. The invention further refers to polyester polyols which are obtained by reaction of cis/trans DHMTHF mixtures with a dicarboxylic acid. The invention further relates to polyurethanes and compositions containing a polyester polyol comprising DHMTHF, in particular to such polyurethane-containing (adhesive) compositions.
专利号:US-4472568-A 优先权日:1981-11-12 标 题:Process for the preparation of polyamines from N-monoaryl-N',N'-dialkyl urea compounds and their use for the synthesis of polyurethanes 发明人:RASSHOFER WERNER; GROEGLER GERHARD 权利人:BAYER AG 摘要:This invention relates to an improved process for the preparation of aromatic polyamines containing urethane and/or biuret and/or urea and/or isocyanurate groups and preferably also ether groups by the hydrolysis of poly-N-monoaryl-N',N'-dialkyl urea compounds (1-aryl-3,3-dialkyl ureas). The ureas are obtained by the reaction of secondary aliphatic, cycloaliphatic or saturated heterocyclic amines with divalent to tetravalent isocyanate compounds containing isocyanate end groups attached to aromatic residues. The ureas correspond to the general formula: wherein R1, R2 denote alkyl or cycloalkyl groups, or together form a ring and A denotes a divalent to tetravalent residue attached to the ureas by aromatic groups. Hydrolysis is carried out in the presence of water and up to two equivalents of a base containing hydroxide ions and/or up to two equivalents of a compound containing tertiary amino groups, optionally in the presence of solvents. The use of the polyamines obtained by this process for the synthesis of polyurethanes is also described.
专利号:US-9409945-B2 优先权日:1999-10-04 标 题 :Combinatorial synthesis of libraries of macrocyclic compounds useful in drug discovery 发明人:DESLONGCHAMPS PIERRE; DORY YVES; BERTHIAUME GILLES; OUELLET LUC; LAN RUOXI 权利人:OCERA THERAPEUTICS INC 摘要:A library of macrocyclic compounds of the formula (I) n n n n n n n n n n n n where part (A) is a n n n n n n n n n n n n n n n n  bivalent radical, a —(CH 2 ) y — bivalent radical or a covalent bond; n where part (B) is a n n n n n n n n n n n n n n n n  bivalent radical, a —(CH 2 ) z — bivalent radical, or a covalent bond; n where part (C) is a n n n n n n n n n n n n n n n n  bivalent radical, a —(CH 2 ) t — bivalent radical, or a covalent bond; and n where part (T) is a —Y-L-Z— radical wherein Y is CH 2 or CO, Z is NH or O and L is a bivalent radical. These compounds are useful for carrying out screening assays or as intermediates for the synthesis of other compounds of pharmaceutical interest. A process for the preparation of these compounds in a combinatorial manner, is also disclosed.
专利号:US-12365760-B2 优先权日:2019-05-13 标题 :Process for the synthesis of polycarbonates from cyclic monothiocarbonates 发明人:RUDOLF PETER; THIEL INDRE; WURM THOMAS MAXIMILIAN 权利人:BASF SE 摘要:A process can be used for the synthesis of compounds containing at least one non-cyclic carbonate group, wherein a compound A) containing at least one five-membered cyclic monothiocarbonate group is reacted with at least one hydroxy group of a compound B) or of compound A) itself.
专利号:WO-2009135600-A1 优先权日:2008-05-07 标题:Catalysts for the synthesis of polyurethanes 发明人:LINDNER STEFAN; BAHNMUELLER STEFAN; SCHMIDT AXEL; WEIKARD JAN; BUCHMEISER MICHAEL; BANTU BHASKER; FRIEDERICHS WOLFGANG; KRAUSE JENS; REITER STEPHAN 权利人:BAYER MATERIALSCIENCE AG; LINDNER STEFAN; BAHNMUELLER STEFAN; SCHMIDT AXEL; WEIKARD JAN; BUCHMEISER MICHAEL; BANTU BHASKER; FRIEDERICHS WOLFGANG; KRAUSE JENS; REITER STEPHAN 摘要:The invention relates to novel catalysts for the synthesis of polyurethanes, represented by general formula (I) or (II), or compounds obtained by reacting a metal salt of the metals magnesium, calcium, yttrium, lanthanum, titanium, zirconium, manganese, iron, cobalt, zinc, aluminium, tin, comprising an anion from the group fluoride, chloride, bromide, sulphonate, trifluoromethanesulphonate, methanesulphonate, benzolsulphonate, para-toluenesulphonate, carboxy-C1-C10-alkyl, carboxy-C3-C10-cycloalkyl, carboxy- C2-C10-alkenyl, C1-C10-alkoxy, acetylacetonate, trifluoroacetlyacetonate or hexafluoroacetylacetonate, with N-heterocyclic compounds of general structure I; or with N-heterocyclic compounds of general structure II; or with N-heterocyclic compounds of general structure III.
专利号:US-2023151394-A1 优先权日:2020-03-31 标题 :Biologic synthesis of diols from amino acids 发明人:ZENG AN-PING; LIU YONGFEI 权利人:TAIZHOU SIMPLU TECH CO LTD 摘要:A method for the enzymatically catalyzed synthesis of a diol from an amino acid includes enzymatically hydroxylating the amino acid, enzymatically deaminating the amino acid, the deamination resulting in the formation of an oxo group at the position of the amino group, enzymatically decarboxylating the amino acid, and enzymatically hydrogenating the oxo group resulting from the deamination reaction.