CAS: 430-67-1; 2,2-Difluoroethylamine

相似化合物

79667-91-7 354-38-1 815-06-5

上下游产品

CAS号1178819-40-3 N-(2,2-difluoro... | CAS号338-65-8 2-氯-1,1-二氟乙烷 | CAS号359-07-9 1-溴-2,2-二氟乙烷 | CAS号359-38-6 2,2-二氟乙酰胺 | CAS号1010422-66-8 4-(2,2-二氟-乙基氨基)... | CAS号864867-22-1 5-bromo-2-(2,2-...

1-溴-2,2-二氟乙烷置于氨,Potassium Iodide体系中,用 二甲基亚砜 作为反应溶剂,化学反应 1.0H,以82%的收率获得产物2,2-二氟乙胺
参考文献:Process For Preparing 2,2-Difluoroethylamine
标题:Process For Preparing 2,2-Difluoroethylamine
摘要:本发明涉及一种从2,2-二氟-1-卤乙烷中使用氨在最大含水量为体积的溶剂中,并在加速与氨反应的催化剂存在下制备2,2-二氟乙胺的方法.

专利信息

专利号:US-2025129021-A1
优先权日:2023-09-19
标 题:Small molecule protein synthesis modulators
发明人：GYGI DAVID; BAHMANYAR SOGOLE SAMI; HAMANN LAWRENCE
权利人:INTERDICT BIO INC
摘要:The present disclosure provides compounds of the formulae herein (e.g., Formula (I), Formula (V)), and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis (e.g., modulating synthesis of BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D). The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.

专利号:US-2022363662-A1
优先权日:2021-04-20
标题 :Compounds as lxr agonists
发明人：PUJALA BRAHMAM; SATHE BALAJI DASHRATH; DANODIA ABHINANDAN; GUPTA ASHU; SONI SANJEEV; KUMAR VIVEK; ANSARI AMANTULLAH; KHAN FARHA; SARKAR ARINDAM; PAYGHAN PAVAN V
权利人:INTEGRAL BIOSCIENCES PRIVATED LTD
摘要:The present invention generally discloses compounds having LXR (the liver X receptor) agonistic activity, to the use of such compounds in the treatment of various disorders such as proliferative disorders, Alzheimer's disease, inflammatory diseases, and diseases characterized by defects in cholesterol and lipid metabolism. Specifically, the present invention discloses compound of formula (IA) which exhibit LXR agonist activity, specifically to LXRβ. The invention also discloses method of synthesis of said compounds, method of using said compounds, pharmaceutical compositions comprising said compounds and method of using thereof.

专利号:US-2023286975-A1
优先权日:2020-07-07
标题:Improved method for the production of lysergic acid diethylamide (lsd) and novel derivatives thereof
发明人：GRILL MATTHIAS
权利人:COMPASS PATHFINDER LTD
摘要:The present invention provides an improved method for the production of lysergic acid diethylamide (LSD) for GMP purposes. Furthermore, the present invention provides novel LSD derivatives of formula I as well as their synthesis and purification. Due to the affinity of the presented substances for the 5-HT 2A receptor, the invention may find application in numerous forms of therapy, such as against depression or drug addiction.

专利号:US-12060343-B2
优先权日:2018-10-22
标题 :Substituted 1,2,4-triazoles as intermediates in the synthesis of TYK2 inhibitors

专利号:US-2023391751-A1
优先权日:2018-10-22
标题 :Substituted 1,2,4-triazoles as intermediates in the synthesis of tyk2 inhibitors

专利号:US-9163020-B2
优先权日:2013-07-17
标 题 :Azaindole compounds, synthesis thereof, and methods of using the same
发明人：SHIRUDE PRAVIN S; NAIK MARUTI N; SHINDE VIKAS NARAYAN; PEER MOHAMED SHAHUL HAMEED; CHATTERJI MONALISA; SHINDIL RADHA K
权利人:GLOBAL ALLIANCE FOR TB DRUG DEV; ASTRAZENECA AB; FOUNDATION FOR NEGLECTED DISEASE RES
摘要:The invention provides compounds of formula (I) and methods of treating a Mycobacterium infection or tuberculosis, or inhibiting DprE1 with the same.