CAS: 1562-00-1; Sodium Isethionate

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77281-03-9 107-36-8 57267-78-4

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专利信息

专利号:US-4828849-A
优先权日:1988-01-14
标题 :Surfactant inhibition of dental plaque
发明人：LYNCH DONALD M; APPELBAUM BENJAMIN
权利人:WARNER LAMBERT CO
摘要:The invention provides an oral preparation or composition such as a mouthwash, mouthrinse, toothpaste and the like containing certain classes of surfactants which act to inhibit plaque formation by inhibiting the initial adherence of bacteria to the dentin surfaces and in the case of one class of surfactants additionally inhibiting the glucosyl transferase catalysis to prevent the synthesis of extracellular polysaccharides from sucrose. n The surfactants comprise substituted taurines, substituted isethionates and substituted hydroxy sultaines in which the substituents are long chain hydrocarbon radicals. The surfactants are employed in the aqueous-based oral compositions at concentrations between about 0.00001M to 0.1M to effect inhibition.

专利号:US-5053530-A
优先权日:1990-04-10
标 题 :Preparation of isethionic acid with organic acid
发明人：ROBERTS JOHN S; MARK HAROLD W
权利人:PHILLIPS PETROLEUM CO
摘要:Synthesis of isethionic acid comprising contacting an alkali metal isethionate and an organic acid.

专利号:US-2004053999-A1
优先权日:1997-09-17
标题 :Novel compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:US-6124496-A
优先权日:1998-10-16
标题 :Method of preparing N-(2-aminoalkyl)-2-aminoethoxylate ethane sulfonate
发明人：WU JONG-FU; CHENG KUN-LIN; CHEN WEN-JUNG
权利人:CHINA TEXTILE INST
摘要:The present invention relates to a synthesis method of thionate diamine by the reaction of alkali metal isethionate with diols to form alkali metal isethionate ethoxylate having the following structural formula: n n HO(CH.sub.2 CH.sub.2 O).sub.n CH.sub.2 CH.sub.2 SO.sub.3 A n n The above isethionate ethoxylate is then reacted with aliphatic diamine having a Carbon number of 2 to 6 to form a series of N-(2-aminoalkyl)-2-aminoethyoxylate ethane sulfonate having the following structure formula: n n H.sub.2 N--(CH.sub.2).sub.m --NH--(CH.sub.2 CH.sub.2 O).sub.n CH.sub.2 n n CH 2 SO 3 A n wherein m=2-12 n n=1-3 n A=K or Na

专利号:US-6150403-A
优先权日:1997-10-14
标 题 :Topical compositions for regulating the oily/shiny appearance of skin
发明人：BIEDERMANN KIMBERLY A; SCHUBERT HARRY L; PARRAN JR JOHN J
权利人:PROCTER & GAMBLE
摘要:The present invention relates to methods for inhibiting sebaceous gland activity in mammalian skin comprising administration of a topical composition comprising dehydroacetic acid or pharmaceutically acceptable salts thereof, and a dermatologically-acceptable carrier. The present invention also relates to methods and topical compositions further comprising agents which regulate the oily and/or shiny appearance of skin, and agents which treat acne and related skin disorders in mammalian skin and scalp. Methods of reducing sebum synthesis with the use of dehydroacetic acid, methods of regulating the oily and/or shiny appearance of skin, and methods of treating acne and other skin disorders are also encompassed by the present invention.

专利号:US-6225341-B1
优先权日:1995-02-27
标 题:Compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A
权利人:GILEAD SCIENCES INC
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.