CAS: 34552-83-5; 4-(4-(4-Chlorophenyl)-4-Hydroxypiperidin-1-yl)-N,N-Dimethyl-2,2-Diphenylbutanamide Hydrochloride

上下游产品

4-(4-chlorophenyl)-4-hydroxypiperidine N-(dihydro-3,3-diphenyl-2(3H)-furanylidene)-N-methylmethanaminium bromide 4-methyl-2-pentanone

4-(4-氯苯基)-4-羟基哌啶,3,3-二苯基四氢呋喃-2-亚基二甲基溴化胺置于potassium Iodide Sodium Carbonate,盐酸体系中,用 甘油缩甲醛,异丙醇 作为反应溶剂,化学反应 2.58H,以67%的收率获得产物盐酸洛哌丁胺
参考文献:Wo2008/80601
标题:Wo2008/80601

专利信息

专利号:US-9617372-B2
优先权日:2012-10-24
标 题 :Sulphur-comprising polyaromatic polyamine that can be used in the synthesis of polyurea
发明人：FEDURCO MILAN; RIBEZZO MARCO
权利人:MICHELIN & CIE; MICHELIN RECH TECH
摘要:A sulphur-comprising polyaromatic polyamine compound can be used as a monomer or prepolymer, when n is different from zero, in the synthesis of polyurea. The compound corresponds to the formula (I):n nH 2 N—Ar 1 —NH—CH 2 —CH(OH)—(CH 2 ) m —O—Z 1 —O—(CH 2 ) m —CH(OH)—CH 2 —[X] n —HN—Ar 2 —NH 2 n nin which X represents the string:n n—HN—Ar 3 —NH—(CH 2 )—CH(OH)—(CH 2 ) m —O—Z 2 —O—(CH 2 ) m —CH(OH)—(CH 2 )—n nand in which n represents an integer equal to zero or different from zero; m, which are identical or different, represent an integer within a range from 1 to 10; Z 1 and Z 2 , which are identical or different, represent a divalent bonding group comprising from 1 to 30 carbon atoms; and Ar 1 , Ar 2 and Ar 3 , which are identical or different, each represent a phenylene group, at least one of these phenylene groups bearing one, two, three or four groups of formula —S x —R in which “xâ€? is an integer from 1 to 8 and R represents hydrogen or a hydrocarbon group which can comprise a heteroatom and which comprises from 1 to 10 carbon atoms.

专利号:US-2025206743-A1
优先权日:2022-03-25
标 题:Tyk2 inhibitor synthesis and intermediates thereof
发明人：MASSE CRAIG E; PHADKE AVINASH S; LAWSON JON P; LEVY STUART; YANG XIAOWEI; WU GUISHENG; FAN SHUFENG
权利人:TAKEDA PHARMACEUTICALS CO
摘要:Described herein are methods of synthesis of a tyrosine-protein kinase 2 (TYK2) inhibitor and to intermediate compounds of the synthesis and methods of making the intermediates. Also provided are pharmaceutically acceptable compositions including compounds prepared by the synthetic method and methods of treating disorders using the same.

专利号:WO-2011132036-A1
优先权日:2010-04-22
标 题:Composite grapheno-metal oxide platelet method of preparation and applications
发明人：MAGALHAES MENDES ADELIO MIGUEL; PACHECO TANAKA DAVID ALFREDO
权利人:UNIV DO PORTO; MAGALHAES MENDES ADELIO MIGUEL; PACHECO TANAKA DAVID ALFREDO
摘要:The present invention relates to the method of preparation and applications of composite catalyst of grapheno-metal oxide. Graphene platelets demonstrated to be very convenient support for metal-oxides catalysts. In particular, grapheno-metal oxide platelets can be used advantageously in organic synthesis, solar cells, solar hydrogen production and synthesis of methanol, taking advantage of metal-oxide semi-conductor properties or just of catalytic properties.

专利号:US-8906425-B2
优先权日:2003-06-13
标 题:Stimulation of the synthesis of the activity of an isoform of lysyl oxidase-like LOXL for stimulating the formation of elastic fibers
发明人：PERRIER ERIC; CENIZO VALÉRIE; BOUEZ CHARBEL; SOMMER PASCAL; DAMOUR ODILE; GLEYZAL CLAUDINE; ANDRE VALÉRIE; REYMERMIER CORINNE
权利人:PERRIER ERIC; CENIZO VALÉRIE; BOUEZ CHARBEL; SOMMER PASCAL; DAMOUR ODILE; GLEYZAL CLAUDINE; ANDRE VALÉRIE; REYMERMIER CORINNE; BASF BEAUTY CARE SOLUTIONS F; CENTRE NAT RECH SCIENT
摘要:The invention relates to the stimulation of the synthesis and of the activity of an isoform of lysyl oxidase, and more particularly of the LOXL (lysyl oxidase-like) isoform. The invention relates notably to a method of identifying an active principle which stimulates the formation of elastic fibers. The aim of the invention is mainly to provide such a method of identification so as to provide compositions which enable stimulating the formation of elastic fibers.

专利号:EP-0082618-B1
优先权日:1981-12-23
标题 :Method of preparing a polymeric coating composition
摘要:A method of preparing a storage-stable one-part reactive liquid thermal curing polymeric coating composition from an isocyanate-functional polymeric compound which has a substantial portion of its isocyanate groups masked with an isocvanate masking agent, and a crosslinking agent which is substantially insoluble in aprotic solvents. These liquid compositions are homogeneous even when free of solvents. Preferably the crosslinking agent is a crystalline polyol. The method involves the synthesis of a solubilizing oligomer which is formed by the partial reaction of the crosslinking agent and the unmasked isocyanate-functional polymeric compound. The thermal curing of these compositions results in polymeric coatings which possess superior physical properties. These cured coatings are particularly useful in the manufacture of retroreflective sheeting.

专利号:US-9757463-B2
优先权日:2012-06-15
标题 :Linear polyester and semi-linear glycidol polymer systems: formulation and synthesis of novel monomers and macromolecular structures
发明人：HARTH EVA M; BEEZER DAIN B; LI GUANGZHAO; SPEARS BENJAMIN R; STEVENS DAVID M
权利人:UNIV VANDERBILT
摘要:Disclosed herein are glycidol-based polymers, nanoparticles, and methods related thereto useful for drug delivery. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.